PMID- 27293539 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20160613 LR - 20220317 IS - 2042-0188 (Print) IS - 2042-0196 (Electronic) IS - 2042-0188 (Linking) VI - 7 IP - 3 DP - 2016 Jun TI - Management of diabetes in Morocco: results of the International Diabetes Management Practices Study (IDMPS) - wave 5. PG - 101-9 LID - 10.1177/2042018816643227 [doi] AB - OBJECTIVES: The International Diabetes Mellitus Practice Study (IDMPS) is a 5-year survey documenting changes in diabetes treatment practices in developing countries. The primary objective of this survey was to assess the therapeutic management of type 2 diabetes mellitus (T2DM) in real-life medical practice. The secondary objectives were to evaluate the clinical management of type 1 diabetes mellitus (T1DM) and to assess the proportion of all diabetic patients failing to reach the glycated haemoglobin (HbA1c) <7% target. METHODS: Data were analysed for 738 patients (240 with T1DM and 498 with T2DM) included in wave 5 of the IDMPS in Morocco in 2011. RESULTS: Nearly two-thirds (61%) of T2DM patients were treated with oral glucose-lowering drugs (OGLDs) alone, 13.1% were treated with insulin alone and 23.3% were treated with OGLDs plus insulin. Insulin use was less frequent, was initiated later and involved a greater use of premixes versus basal/prandial schedules compared to other populations evaluated in the IDMPS. The majority (92.5%) of T1DM patients were treated with insulin alone and the remainder received insulin plus an OGLD. Insulin protocols included basal + prandial dosing (37.5%) and premix preparations (41.3%). The recommended target of HbA1c <7% was achieved by only 22.2% of T1DM patients and 26.8% of T2DM patients. More macrovascular but fewer microvascular complications were reported in T2DM compared to T1DM patients. Late complications increased with disease duration so that 20 years after diagnosis, 75.7% of T2DM patients were found to have at least one late complication. CONCLUSIONS: The clinical burden of diabetes is high in Morocco and the majority of patients do not achieve the recommended glycaemia target, suggesting that there is a huge gap between evidence-based diabetic management and real-life practice. Better education of patients and improved compliance with international recommendations are necessary to deliver a better quality of diabetic care. FAU - Chadli, Asmae AU - Chadli A AD - Ibn Rushd University Hospital, Casablanca, Morocco. FAU - El Aziz, Siham AU - El Aziz S AD - Ibn Rushd University Hospital, Casablanca, Morocco. FAU - El Ansari, Nawal AU - El Ansari N AD - Mohammed VI University Hospital, Marrakesh, Morocco. FAU - Ajdi, Farida AU - Ajdi F AD - Hassan II University Hospital, Fez, Morocco. FAU - Seqat, Mehdi AU - Seqat M AD - Sanofi Maroc, Casablanca, Morocco. FAU - Latrech, Hanane AU - Latrech H AD - Mohamed VI University Hospital, Oujda, Morocco. FAU - Belmejdoub, Ghizlaine AU - Belmejdoub G AD - Military Hospital Instruction Mohammed V, Rabat, Morocco. LA - eng PT - Journal Article DEP - 20160413 PL - United States TA - Ther Adv Endocrinol Metab JT - Therapeutic advances in endocrinology and metabolism JID - 101532143 PMC - PMC4892401 OTO - NOTNLM OT - basal-prandial OT - complications OT - diabetes OT - glycaemic control OT - insulin OT - management COIS- Conflict of interest statement: The author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: A. Chadli, S. El Aziz, N. El Ansari, F. Ajdi, H. Latrech and G. Belmejdoub declare that there is no conflict of interest. M. Seqat is an employee of Sanofi-Aventis, Morocco. EDAT- 2016/06/14 06:00 MHDA- 2016/06/14 06:01 PMCR- 2016/06/01 CRDT- 2016/06/14 06:00 PHST- 2016/06/14 06:00 [entrez] PHST- 2016/06/14 06:00 [pubmed] PHST- 2016/06/14 06:01 [medline] PHST- 2016/06/01 00:00 [pmc-release] AID - 10.1177_2042018816643227 [pii] AID - 10.1177/2042018816643227 [doi] PST - ppublish SO - Ther Adv Endocrinol Metab. 2016 Jun;7(3):101-9. doi: 10.1177/2042018816643227. Epub 2016 Apr 13.