PMID- 27294332
OWN - NLM
STAT- MEDLINE
DCOM- 20180416
LR  - 20181113
IS  - 2045-2322 (Electronic)
IS  - 2045-2322 (Linking)
VI  - 6
DP  - 2016 Jun 13
TI  - Myopic Macular Retinoschisis in Teenagers: Clinical Characteristics and Spectral 
      Domain Optical Coherence Tomography Findings.
PG  - 27952
LID - 10.1038/srep27952 [doi]
LID - 27952
AB  - To investigate the morphological characteristics of myopic macular retinoschisis 
      (MRS) in teenagers with high myopia, six male (9 eyes) and 3 female (4 eyes) 
      teenagers with typical MRS identified from chart review were evaluated. All cases 
      underwent complete ophthalmic examinations including best corrected visual acuity 
      (BCVA), indirect ophthalmoscopy, colour fundus photography, B-type 
      ultrasonography, axial length measurement, and spectral-domain optical coherence 
      tomography (SD-OCT). The average age was 17.8 +/- 1.5 years, average refractive 
      error was -17.04 +/- 3.04D, average BCVA was 0.43 +/- 0.61, and average axial length 
      was 30.42 +/- 1.71 mm. Myopic macular degenerative changes (MDC) by colour fundus 
      photographs revealed Ohno-Matsui Category 1 in 4 eyes, and Category 2 in 9 eyes. 
      Posterior staphyloma was found in 9 eyes. SD-OCT showed outer MRS in all 13 eyes, 
      internal limiting membrane detachment in 7 eyes, vascular microfolds in 2 eyes, 
      and inner MRS in 1 eye. No premacular structures such as macular epiretinal 
      membrane or partially detached posterior hyaloids were found. Our results showed 
      that MRS rarely occurred in highly myopic teenagers, and was not accompanied by 
      premacular structures, severe MDC, or even obvious posterior staphyloma. This 
      finding indicates that posterior scleral expansion is probably the main cause of 
      MRS.
FAU - Sun, Chuan-Bin
AU  - Sun CB
AD  - Eye Center, Second Affiliated Hospital of Zhejiang University School of Medicine, 
      Hangzhou 310009, China.
FAU - You, Yong-Sheng
AU  - You YS
AD  - Eye Center, Second Affiliated Hospital of Zhejiang University School of Medicine, 
      Hangzhou 310009, China.
FAU - Liu, Zhe
AU  - Liu Z
AD  - Eye Center, Zhejiang Provincial People's Hospital, Hangzhou 310015, China.
FAU - Zheng, Lin-Yan
AU  - Zheng LY
AD  - Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China.
FAU - Chen, Pei-Qing
AU  - Chen PQ
AD  - Eye Center, Second Affiliated Hospital of Zhejiang University School of Medicine, 
      Hangzhou 310009, China.
FAU - Yao, Ke
AU  - Yao K
AD  - Eye Center, Second Affiliated Hospital of Zhejiang University School of Medicine, 
      Hangzhou 310009, China.
FAU - Xue, An-Quan
AU  - Xue AQ
AD  - Eye Hospital, Wenzhou Medical University, Wenzhou 325027, China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20160613
PL  - England
TA  - Sci Rep
JT  - Scientific reports
JID - 101563288
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Female
MH  - Humans
MH  - Macula Lutea/diagnostic imaging/pathology
MH  - Macular Degeneration/complications/*diagnostic imaging/*pathology
MH  - Male
MH  - Myopia, Degenerative/*diagnostic imaging/*pathology
MH  - Retinoschisis/complications/*diagnostic imaging/*pathology
MH  - *Tomography, Optical Coherence
MH  - Young Adult
PMC - PMC4904792
EDAT- 2016/06/15 06:00
MHDA- 2018/04/17 06:00
PMCR- 2016/06/13
CRDT- 2016/06/14 06:00
PHST- 2015/06/25 00:00 [received]
PHST- 2016/05/26 00:00 [accepted]
PHST- 2016/06/14 06:00 [entrez]
PHST- 2016/06/15 06:00 [pubmed]
PHST- 2018/04/17 06:00 [medline]
PHST- 2016/06/13 00:00 [pmc-release]
AID - srep27952 [pii]
AID - 10.1038/srep27952 [doi]
PST - epublish
SO  - Sci Rep. 2016 Jun 13;6:27952. doi: 10.1038/srep27952.