PMID- 27300094
OWN - NLM
STAT- MEDLINE
DCOM- 20190610
LR  - 20220408
IS  - 1439-4421 (Electronic)
IS  - 0941-3790 (Linking)
VI  - 80
IP  - 6
DP  - 2018 Jun
TI  - [Trends in Abuse of Biogenic Drugs in Parts of Germany 2007-2013].
PG  - 532-539
LID - 10.1055/s-0042-108644 [doi]
AB  - AIM OF THE STUDY: Based on an abundance of information on the internet, 
      psychotropic plants and mushrooms are of increasing relevance as legal and cheap 
      alternatives to other illicit drugs. Due to the lack of a German database, the 
      abuse of selected biogenic drugs using reported exposures to 3 German Poison 
      Information Centres (PICs) was examined. METHODS: Information on abuse of 
      biogenic drugs was collected from the German PICs in Berlin, Erfurt and Fribourg 
      (2007-2013). RESULTS: 602 drug abuses were reported to the selected PICs. 52% 
      reported consumption of tropane alkaloid-containing plants (Angel's trumpet, 
      Thorn apple, Belladonna), 25% of psilocybin-containing mushrooms and 10% of 
      nutmeg. Angel's trumpet was identified as the most abused plant. Consumers of 
      tropane alkaloid-containing plants were mainly adolescents, whereas the majority 
      of the abusers of psilocybin-containing mushrooms and nutmeg were rather young 
      grown-ups and school children, respectively. A preponderance of moderate and 
      severe effects (55%) could be noticed for exposures to tropane 
      alkaloid-containing plants. More than 90% of suspected cases of tropane 
      alkaloid-containing as well as psilocybin-containing plants abuse resulted in the 
      treatment recommendation 'surveillance in hospital'. Mydriasis, hallucinations, 
      tachycardia and agitation were the main symptoms after the abuse of biogenic 
      drugs. CONCLUSIONS: The data from the PICs suggest abuse of biogenic drugs in 
      parts of Germany. A decreasing trend is observed, probably caused by the 
      competition with new synthetic designer drugs. The results underline the 
      dominance of Angel's trumpet in the abuse of biogenic drugs and emphasize the 
      importance of easy accessibility for the abuse of biogenic drugs. Unexpectedly, 
      the number of nutmeg abuse cases increased during the investigated period.
CI  - (c) Georg Thieme Verlag KG Stuttgart . New York.
FAU - Pietsch, J
AU  - Pietsch J
AD  - Institut fur Rechtsmedizin, TU Dresden, Dresden.
FAU - Scheffel, K
AU  - Scheffel K
AD  - Institut fur Rechtsmedizin, TU Dresden, Dresden.
FAU - Acquarone, D
AU  - Acquarone D
AD  - Giftnotruf, Charite-Universitatsklinikum Berlin, Berlin.
FAU - Koch, I
AU  - Koch I
AD  - Giftnotruf, Charite-Universitatsklinikum Berlin, Berlin.
FAU - Deters, M
AU  - Deters M
AD  - Giftnotruf, c/o HELIOS Klinikum Erfurt GmbH, Erfurt.
FAU - Hermanns-Clausen, M
AU  - Hermanns-Clausen M
AD  - Zentrum fur Kinder- und Jugendmedizin, Vergiftungs-Informations-Zentrale, 
      Universitatsklinikum Freiburg, Freiburg.
LA  - ger
PT  - Journal Article
TT  - Entwicklung des Missbrauchs psychotroper Pflanzen und Pilze in Deutschland - 
      Interpretation der Zahlen aus 3 Giftinformationszentren fur die Jahre 2007-2013.
DEP - 20160614
PL  - Germany
TA  - Gesundheitswesen
JT  - Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes 
      (Germany))
JID - 9204210
RN  - 0 (Hallucinogens)
SB  - IM
MH  - Adolescent
MH  - Agaricales
MH  - Child
MH  - Germany
MH  - *Hallucinogens
MH  - Humans
MH  - Mydriasis
MH  - Plants
MH  - *Substance-Related Disorders
COIS- Die Autoren geben an, dass kein Interessenkonflikt besteht.
EDAT- 2016/06/15 06:00
MHDA- 2019/06/14 06:00
CRDT- 2016/06/15 06:00
PHST- 2016/06/15 06:00 [pubmed]
PHST- 2019/06/14 06:00 [medline]
PHST- 2016/06/15 06:00 [entrez]
AID - 10.1055/s-0042-108644 [doi]
PST - ppublish
SO  - Gesundheitswesen. 2018 Jun;80(6):532-539. doi: 10.1055/s-0042-108644. Epub 2016 
      Jun 14.