PMID- 27305110
OWN - NLM
STAT- MEDLINE
DCOM- 20170424
LR  - 20181113
IS  - 1678-4170 (Electronic)
IS  - 0066-782X (Print)
IS  - 0066-782X (Linking)
VI  - 107
IP  - 1
DP  - 2016 Jul
TI  - Reproducibility of Gadolinium Enhancement Patterns and Wall Thickness in 
      Hypertrophic Cardiomyopathy.
PG  - 48-54
LID - S0066-782X2016005016104 [pii]
LID - 10.5935/abc.20160087 [doi]
AB  - BACKGROUND: Reproducibility data of the extent and patterns of late gadolinium 
      enhancement (LGE) in hypertrophic cardiomyopathy (HCM) is limited. OBJECTIVE: To 
      explore the reproducibility of regional wall thickness (WT), LGE extent, and LGE 
      patterns in patients with HCM assessed with cardiac magnetic resonance (CMR). 
      METHODS: The extent of LGE was assessed by the number of segments with LGE, and 
      by the total LV mass with LGE (% LGE); and the pattern of LGE-CMR was defined for 
      each segment. RESULTS: A total of 42 patients (672 segments) with HCM constituted 
      the study population. The mean WT measurements showed a mean difference between 
      observers of -0.62 +/- 1.0 mm (6.1%), with limits of agreement of 1.36 mm; -2.60 mm 
      and intraclass correlation coefficient (ICC) of 0.95 (95% CI 0.93-0.96). Maximum 
      WT measurements showed a mean difference between observers of -0.19 +/- 0.8 mm 
      (0.9%), with limits of agreement of 1.32 mm; -1.70 mm, and an ICC of 0.95 (95% CI 
      0.91-0.98). The % LGE showed a mean difference between observers of -1.17 +/- 1.2 % 
      (21%), with limits of agreement of 1.16%; -3.49%, and an ICC of 0.94 (95% CI 
      0.88-0.97). The mean difference between observers regarding the number of 
      segments with LGE was -0.40 +/- 0.45 segments (11%), with limits of agreement of 
      0.50 segments; -1.31 segments, and an ICC of 0.97 (95% CI 0.94-0.99). 
      CONCLUSIONS: The number of segments with LGE might be more reproducible than the 
      percent of the LV mass with LGE.
FAU - Rodriguez-Granillo, Gaston A
AU  - Rodriguez-Granillo GA
AD  - Department of Cardiovascular Imaging, Diagnostico Maipu, Buenos Aires, Argentina.
FAU - Deviggiano, Alejandro
AU  - Deviggiano A
AD  - Department of Cardiovascular Imaging, Diagnostico Maipu, Buenos Aires, Argentina.
FAU - Capunay, Carlos
AU  - Capunay C
AD  - Department of Cardiovascular Imaging, Diagnostico Maipu, Buenos Aires, Argentina.
FAU - Zan, Macarena C De
AU  - Zan MC
AD  - Department of Cardiovascular Imaging, Diagnostico Maipu, Buenos Aires, Argentina.
FAU - Carrascosa, Patricia
AU  - Carrascosa P
AD  - Department of Cardiovascular Imaging, Diagnostico Maipu, Buenos Aires, Argentina.
LA  - eng
LA  - por
PT  - Journal Article
PT  - Observational Study
DEP - 20160610
PL  - Brazil
TA  - Arq Bras Cardiol
JT  - Arquivos brasileiros de cardiologia
JID - 0421031
RN  - AU0V1LM3JT (Gadolinium)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Cardiomyopathy, Hypertrophic/*diagnostic imaging
MH  - Female
MH  - *Gadolinium
MH  - Heart Ventricles/*diagnostic imaging
MH  - Humans
MH  - Magnetic Resonance Imaging, Cine/*methods
MH  - Male
MH  - Middle Aged
MH  - Observer Variation
MH  - Radiographic Image Enhancement/*methods
MH  - Reference Values
MH  - Reproducibility of Results
MH  - Risk Assessment
MH  - Time Factors
MH  - Ventricular Dysfunction, Left/diagnostic imaging
PMC - PMC4976956
COIS- Potential Conflict of Interest No potential conflict of interest relevant to this 
      article was reported.
EDAT- 2016/06/16 06:00
MHDA- 2017/04/25 06:00
PMCR- 2016/07/01
CRDT- 2016/06/16 06:00
PHST- 2015/11/09 00:00 [received]
PHST- 2016/04/13 00:00 [accepted]
PHST- 2016/06/16 06:00 [entrez]
PHST- 2016/06/16 06:00 [pubmed]
PHST- 2017/04/25 06:00 [medline]
PHST- 2016/07/01 00:00 [pmc-release]
AID - S0066-782X2016005016104 [pii]
AID - 10.5935/abc.20160087 [doi]
PST - ppublish
SO  - Arq Bras Cardiol. 2016 Jul;107(1):48-54. doi: 10.5935/abc.20160087. Epub 2016 Jun 
      10.