PMID- 27306197
OWN - NLM
STAT- MEDLINE
DCOM- 20170609
LR  - 20170609
IS  - 1469-8730 (Electronic)
IS  - 0967-1994 (Linking)
VI  - 24
IP  - 5
DP  - 2016 Oct
TI  - Duration of spermatogenesis and daily sperm production in the rodent Proechimys 
      guyannensis.
PG  - 783-93
LID - 10.1017/S0967199416000137 [doi]
AB  - The spiny rat (Proechimys guyannensis) is a neotropical rodent that is used in 
      biomedical research, particularly research related to chronic resistance to 
      epilepsy and infectious diseases. To our knowledge, there are few reports 
      concerning the reproductive biology of this species. Therefore, besides providing 
      basic biometric and morphometric data, in the present study we investigated 
      testis function and spermatogenesis in adult spiny rats. The mean testis weight 
      and gonadosomatic index obtained were 1.63 +/- 0.2 g and 1.15 +/- 0.1% respectively. 
      Based on the development of the acrosomic system, 12 stages of the seminiferous 
      epithelium cycle were characterized. Stages VI and VII presented the highest 
      frequencies (~17-19%), whilst stages II to V showed the lowest frequencies 
      (~2-4%). The most advanced germ cell types labelled at 1 h or 20 days after BrdU 
      injections were respectively preleptotene/leptotene spermatocytes at stage VII 
      and elongated spermatids at stage III. The mean duration of one cycle was 7.5 +/- 
      0.01 days and the entire spermatogenic process lasted 33.7 +/- 0.06 days (~4.5 
      cycles). The seminiferous tubules (ST) occupied ~96 +/- 1% of the testis 
      parenchyma, whereas Leydig cells comprised only 1.5 +/- 0.4%. The number of Sertoli 
      cells (SC) per testis gram and the SC efficiency (spermatids/SC) were 
      respectively 78 x 106 +/- 11 x 106 and 7.9 +/- 1. The daily sperm production per 
      testis gram (spermatogenic efficiency; daily sperm production (DSP)/g/testis) was 
      78 x 106 +/- 8 x 106. To our knowledge, this spermatogenic efficiency is among the 
      highest found for mammals investigated to date and is probably related to the 
      very short duration of spermatogenesis and the very high ST percentage and SC 
      number obtained for this species.
FAU - Lara, Nathalia L M
AU  - Lara NL
AD  - Laboratory of Cellular Biology,Department of Morphology,Federal University of 
      Minas Gerais,Belo Horizonte,Minas Gerais 31270-901,Brazil.
FAU - Santos, Ivan C
AU  - Santos IC
AD  - Department of Biosystems Engineering,Federal University of Sao Joao Del-Rei,Sao 
      Joao Del-Rei,Minas Gerais 36307-352,Brazil.
FAU - Costa, Guilherme M J
AU  - Costa GM
AD  - Laboratory of Cellular Biology,Department of Morphology,Federal University of 
      Minas Gerais,Belo Horizonte,Minas Gerais 31270-901,Brazil.
FAU - Cordeiro-Junior, Dirceu A
AU  - Cordeiro-Junior DA
AD  - Laboratory of Cellular Biology,Department of Morphology,Federal University of 
      Minas Gerais,Belo Horizonte,Minas Gerais 31270-901,Brazil.
FAU - Almeida, Antonio C G
AU  - Almeida AC
AD  - Department of Biosystems Engineering,Federal University of Sao Joao Del-Rei,Sao 
      Joao Del-Rei,Minas Gerais 36307-352,Brazil.
FAU - Madureira, Ana P
AU  - Madureira AP
AD  - Department of Biosystems Engineering,Federal University of Sao Joao Del-Rei,Sao 
      Joao Del-Rei,Minas Gerais 36307-352,Brazil.
FAU - Zanini, Marcos S
AU  - Zanini MS
AD  - Department of Veterinary Medicine,Federal University of Espirito 
      Santo,Vitoria,Espirito Santo 29075-910,Brazil.
FAU - Franca, Luiz R
AU  - Franca LR
AD  - Laboratory of Cellular Biology,Department of Morphology,Federal University of 
      Minas Gerais,Belo Horizonte,Minas Gerais 31270-901,Brazil.
LA  - eng
PT  - Journal Article
DEP - 20160616
PL  - England
TA  - Zygote
JT  - Zygote (Cambridge, England)
JID - 9309124
SB  - IM
MH  - Animals
MH  - Leydig Cells/cytology
MH  - Male
MH  - Organ Size
MH  - Rodentia/*physiology
MH  - Seminiferous Epithelium/physiology
MH  - Sertoli Cells/cytology
MH  - Sperm Count
MH  - Spermatogenesis/*physiology
MH  - Spermatozoa/cytology/physiology
MH  - Testis/anatomy & histology/*cytology
OTO - NOTNLM
OT  - P. guyannensis
OT  - Sertoli cell efficiency
OT  - Sperm production
OT  - Spermatogenesis
OT  - Spiny rat
OT  - Testis
EDAT- 2016/06/17 06:00
MHDA- 2017/06/10 06:00
CRDT- 2016/06/17 06:00
PHST- 2016/06/17 06:00 [entrez]
PHST- 2016/06/17 06:00 [pubmed]
PHST- 2017/06/10 06:00 [medline]
AID - S0967199416000137 [pii]
AID - 10.1017/S0967199416000137 [doi]
PST - ppublish
SO  - Zygote. 2016 Oct;24(5):783-93. doi: 10.1017/S0967199416000137. Epub 2016 Jun 16.