PMID- 27307026 OWN - NLM STAT- MEDLINE DCOM- 20170331 LR - 20170331 IS - 1600-0455 (Electronic) IS - 0284-1851 (Linking) VI - 58 IP - 4 DP - 2017 Apr TI - Health economic aspects of evaluation with diffusion weighted MR and MR colonography compared to standard evaluation with colonoscopy and CT before rectal cancer surgery. PG - 435-441 LID - 10.1177/0284185116653281 [doi] AB - Background Colorectal cancer is a frequent type of cancer, and with the risk of synchronous disease, the need for a complete staging leads to an extensive and costly preoperative diagnostic evaluation. Previously we described a total preoperative evaluation using magnetic resonance (MR) colonography and diffusion-weighted MR of the liver. Purpose To compare the economic aspects of this modality with the standard evaluation in an analysis of the different cost drivers. Material and Methods Based on the results from previous studies, two calculations were performed, a theoretical cost calculation and a practical cost calculation. The cost drivers utilized are an average cost based on the cost of all procedures and diagnostic modalities performed in hospitalized patients (DRG) and outpatients (DAGS [Danish outpatient grouping system]) in Denmark. Results The total cost for a full colorectal evaluation and computed tomography (CT) scan of the thorax/abdomen was less for the new modality group in all theoretical models proposed; euro225 using model A, euro322 using model B, and euro383 using model C. Using results from previous studies, the actual difference and the potential difference in cost between the two preoperative diagnostic modalities per patient were euro312 and euro712, respectively. Conclusion This cost analysis shows the cost effectiveness of the new modality as the future standard preoperative diagnostic work-up by reducing total cost and by having a higher sensitivity and completion rate. FAU - Achiam, Michael P AU - Achiam MP AD - 1 Department of Surgical Gastroenterology, Abdominalcenteret, Copenhagen University Hospital, Rigshospitalet, Denmark. FAU - Kjellberg, Jakob AU - Kjellberg J AD - 2 KORA, the Danish Institute for Local and Regional Government Research, Denmark. FAU - Rosenberg, Jacob AU - Rosenberg J AD - 3 Department of Surgical Gastroenterology, Copenhagen University Hospital, Herlev Hospital, Denmark. LA - eng PT - Comparative Study PT - Journal Article DEP - 20160720 PL - England TA - Acta Radiol JT - Acta radiologica (Stockholm, Sweden : 1987) JID - 8706123 SB - IM MH - Colon/diagnostic imaging MH - Colonoscopy/*economics MH - Cost-Benefit Analysis/*economics MH - Denmark MH - Diffusion Magnetic Resonance Imaging/economics MH - Humans MH - Magnetic Resonance Imaging/*economics MH - Rectal Neoplasms/*diagnostic imaging/*economics/surgery MH - Sensitivity and Specificity MH - Tomography, X-Ray Computed/*economics OTO - NOTNLM OT - Health economic OT - colonography OT - computed tomography (CT) OT - cost OT - magnetic resonance imaging (MR) OT - rectal cancer EDAT- 2016/06/17 06:00 MHDA- 2017/04/01 06:00 CRDT- 2016/06/17 06:00 PHST- 2016/06/17 06:00 [pubmed] PHST- 2017/04/01 06:00 [medline] PHST- 2016/06/17 06:00 [entrez] AID - 0284185116653281 [pii] AID - 10.1177/0284185116653281 [doi] PST - ppublish SO - Acta Radiol. 2017 Apr;58(4):435-441. doi: 10.1177/0284185116653281. Epub 2016 Jul 20.