PMID- 27308072
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160616
LR  - 20181113
IS  - 2146-3123 (Print)
IS  - 2146-3131 (Electronic)
IS  - 2146-3123 (Linking)
VI  - 33
IP  - 3
DP  - 2016 May
TI  - Effectiveness of Using Dual-source CT and the Upshot it creates on Both Heart 
      Rate and Image Quality.
PG  - 283-93
LID - 10.5152/balkanmedj.2016.16220 [doi]
AB  - BACKGROUND: Early detection of coronary artery disease (CAD) is important because 
      of the high morbidity and mortality rates. As invasive coronary angiography (ICA) 
      is an invasive procedure, an alternative diagnostic method; coronary computed 
      tomography angiography (CTA), has become more widely used by the improvements in 
      detector technology. AIMS: In this study, we aimed to examine the accuracy and 
      image quality of high-pitch 128-slice dual-source CTA taking the ICA as reference 
      technique. We also aimed to compare the accuracy and image quality between 
      different heart rate groups of >70 beates per minute (bpm) and </=70 bpm. STUDY 
      DESIGN: Retrospective cross-sectional study. METHODS: Among 450 patients who 
      underwent coronary CTA with the FLASH spiral technique, performed with a second 
      generation dual-source computed tomography device with a pitch value of 3.2, 102 
      patients without stent and/or bypass surgery history and clinically suspected 
      coronary artery disease who underwent ICA within 15 days were enrolled. Image 
      quality was assessed by two independent radiologists using a 4-point scale 
      (1=absence of any artifacts- 4=non-evaluable). A stenosis >50% was considered 
      significant on a per-segment, per-vessel, and per-patient basis and ICA was 
      considered the reference method. Radiation doses were determined using dose 
      length product (DLP) values detected by the computed tomography (CT) device. In 
      addition, patients were classified into two groups according to their heart rates 
      as </=70 bpm (73 patients) and >70 bpm (29 patients). The relation between the 
      diagnostic accuracy and heart rate groups were evaluated. RESULTS: Overall, 1495 
      (98%) coronary segments were diagnostic in 102 patients (32 male, 70 female, mean 
      heart rate: 65 bpm). There was a significant correlation between image quality 
      and mean heart rate in the right coronary artery (RCA) segments. The effective 
      radiation dose was 0.98+/-0.09 mili Sievert (mSv). On a per-patient basis, 
      sensitivity, specificity, and positive and negative predictive values were 93.8%, 
      88.8%, 93.8% and 88.8%, respectively. These values were also similar in 
      per-vessel and per-segment basis. Two different groups categorized by mean heart 
      rate had almost similar results in terms of the diagnostic power of dual-source 
      CTA. CONCLUSION: CTA with a high pitch value is a reliable, non-invasive 
      diagnostic method that can CAD with low radiation doses not only in patients with 
      a heart rate below 70 bpm, but also in patients with higher heart rates.
FAU - Selcuk, Tuba
AU  - Selcuk T
AD  - Department of Radiology, Haseki Training and Research Hospital, Istanbul, Turkey; 
      Department of Medical Imaging Techniques, Istanbul Gelisim University Vocational 
      School of Health Services.
FAU - Otcu, Hafize
AU  - Otcu H
AD  - Department of Radiology, Halkali Mehmet Akif Ersoy Thoracic and Cardiovascular 
      Surgery Training and Research Hospital, Istanbul, Turkey.
FAU - Yuceler, Zeyneb
AU  - Yuceler Z
AD  - Department of Radiology, Sereflikochisar Government Hospital, Ankara, Turkey.
FAU - Bilgili, Cigdem
AU  - Bilgili C
AD  - Department of Radiology, Haseki Training and Research Hospital, Istanbul, Turkey.
FAU - Bulakci, Mesut
AU  - Bulakci M
AD  - Department of Radiology, Istanbul University Istanbul School of Medicine, 
      Istanbul, Turkey.
FAU - Savas, Yildiray
AU  - Savas Y
AD  - Department of Radiology, Haseki Training and Research Hospital, Istanbul, Turkey.
FAU - Celik, Omer
AU  - Celik O
AD  - Department of Cardiology, Halkali Mehmet Akif Ersoy Thoracic and Cardiovascular 
      Surgery Training and Research Hospital, Istanbul, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20160501
PL  - Turkey
TA  - Balkan Med J
JT  - Balkan medical journal
JID - 101571817
PMC - PMC4898987
OTO - NOTNLM
OT  - Computed tomography angiography
OT  - coronary arteries
OT  - heart rate
OT  - high-pitch
OT  - low radiation dose
EDAT- 2016/06/17 06:00
MHDA- 2016/06/17 06:01
PMCR- 2016/05/01
CRDT- 2016/06/17 06:00
PHST- 2014/05/03 00:00 [received]
PHST- 2015/08/01 00:00 [accepted]
PHST- 2016/06/17 06:00 [entrez]
PHST- 2016/06/17 06:00 [pubmed]
PHST- 2016/06/17 06:01 [medline]
PHST- 2016/05/01 00:00 [pmc-release]
AID - bmj-33-3-283 [pii]
AID - 10.5152/balkanmedj.2016.16220 [doi]
PST - ppublish
SO  - Balkan Med J. 2016 May;33(3):283-93. doi: 10.5152/balkanmedj.2016.16220. Epub 
      2016 May 1.