PMID- 2731461
OWN - NLM
STAT- MEDLINE
DCOM- 19890721
LR  - 20190515
IS  - 0149-5992 (Print)
IS  - 0149-5992 (Linking)
VI  - 12
IP  - 6
DP  - 1989 Jun
TI  - Correlation between amount of carbohydrate in mixed meals and insulin delivery by 
      artificial pancreas in seven IDDM subjects.
PG  - 427-9
AB  - The effects of mixed meals containing varying amounts of carbohydrate (CHO) on 
      blood glucose levels and insulin delivery by an artificial pancreas were studied 
      in seven insulin-dependent diabetes mellitus subjects. Each patient received, at 
      random over 3 consecutive days, three mixed meals containing 60, 80, and 140 g 
      complex CHOs. There was a high and linear correlation between total amount of 
      insulin delivered to restore blood glucose values and amount of CHO consumed: 
      12.1 +/- 1.3 to 31.2 +/- 5.2 U insulin were needed for 116 +/- 16 to 198 +/- 24 
      min. However, neither the time lapse between the beginning of meal intake and 
      blood glucose increase nor the peaking time for blood glucose variation were 
      significantly different between meals. We suggest that some of the data obtained 
      in this study might be useful in programming an open-loop insulin-infusion 
      system.
FAU - Halfon, P
AU  - Halfon P
AD  - Department of Diabetes, Hotel-Dieu Hospital, Paris, France.
FAU - Belkhadir, J
AU  - Belkhadir J
FAU - Slama, G
AU  - Slama G
LA  - eng
PT  - Clinical Trial
PT  - Comparative Study
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Diabetes Care
JT  - Diabetes care
JID - 7805975
RN  - 0 (Blood Glucose)
RN  - 0 (Dietary Carbohydrates)
SB  - IM
CIN - Diabetes Care. 1990 Jul;13(7):818. PMID: 2201505
MH  - Adult
MH  - Blood Glucose/*metabolism
MH  - Diabetes Mellitus, Type 1/blood/*drug therapy
MH  - Dietary Carbohydrates/*administration & dosage
MH  - Humans
MH  - *Insulin Infusion Systems
MH  - Kinetics
MH  - Random Allocation
EDAT- 1989/06/01 00:00
MHDA- 1989/06/01 00:01
CRDT- 1989/06/01 00:00
PHST- 1989/06/01 00:00 [pubmed]
PHST- 1989/06/01 00:01 [medline]
PHST- 1989/06/01 00:00 [entrez]
AID - 10.2337/diacare.12.6.427 [doi]
PST - ppublish
SO  - Diabetes Care. 1989 Jun;12(6):427-9. doi: 10.2337/diacare.12.6.427.