PMID- 2731529
OWN - NLM
STAT- MEDLINE
DCOM- 19890714
LR  - 20190828
IS  - 0301-5548 (Print)
IS  - 0301-5548 (Linking)
VI  - 58
IP  - 6
DP  - 1989
TI  - Effects of long-term feeding of high-protein or high-fat diets on the response to 
      exercise in the rat.
PG  - 583-90
AB  - The aim of this work was to find by which mechanisms an increased availability of 
      plasma free fatty acids (FFA) reduced carbohydrate utilization during exercise. 
      Rats were fed high-protein medium-chain triglycerides (MCT), high-protein 
      long-chain triglycerides (LCT), carbohydrate (CHO) or high-protein low-fat (HP) 
      diets for 5 weeks, and liver and muscle glycogen, gluconeogenesis and FFA 
      oxidation were studied in rested and trained runner rats. In the rested state the 
      hepatic glycogen store was decreased by fat and protein feeding, whereas soleus 
      muscle glycogen concentration was only affected by high-protein diets. The 
      percentage decrease in liver and muscle glycogen stores, after running, was 
      similar in fat-fed, high-protein and CHO-fed rats. The fact that plasma glucose 
      did not drastically change during exercise could be explained by a stimulation of 
      hepatic gluconeogenesis: the activity of phosphoenolpyruvate carboxykinase 
      (PEPCK) and liver phosphoenolpyruvate (PEP) concentration increased as well as 
      cyclic adenosine monophosphate (AMPc) while liver fructose 2,6-bisphosphate 
      decreased and plasma FFA rose. In contrast, the stimulation of gluconeogenesis in 
      rested HP-, MCT- and LCT-fed rats appears to be independent of cyclic AMP.
FAU - Satabin, P
AU  - Satabin P
AD  - Centre d'Etudes et de Recherches de Medecine Aerospatiale, Paris, France.
FAU - Bois-Joyeux, B
AU  - Bois-Joyeux B
FAU - Chanez, M
AU  - Chanez M
FAU - Guezennec, C Y
AU  - Guezennec CY
FAU - Peret, J
AU  - Peret J
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Eur J Appl Physiol Occup Physiol
JT  - European journal of applied physiology and occupational physiology
JID - 0410266
RN  - 0 (Blood Glucose)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Fats)
RN  - 0 (Dietary Proteins)
RN  - 0 (Fatty Acids, Nonesterified)
RN  - 0 (Fructosediphosphates)
RN  - 0 (Lactates)
RN  - 0 (Liver Glycogen)
RN  - 0 (Pyruvates)
RN  - 0 (Triglycerides)
RN  - 73-89-2 (Phosphoenolpyruvate)
RN  - 79082-92-1 (fructose 2,6-diphosphate)
RN  - 9005-79-2 (Glycogen)
SB  - IM
MH  - Animals
MH  - Blood Glucose/analysis
MH  - *Carbohydrate Metabolism
MH  - Dietary Carbohydrates/administration & dosage
MH  - Dietary Fats/*administration & dosage
MH  - Dietary Proteins/*administration & dosage
MH  - Eating
MH  - Fatty Acids, Nonesterified/blood
MH  - Fructosediphosphates/metabolism
MH  - Glycogen/metabolism
MH  - Lactates/metabolism
MH  - Liver Glycogen/metabolism
MH  - Male
MH  - Muscles/*metabolism
MH  - Phosphoenolpyruvate/metabolism
MH  - *Physical Exertion
MH  - Pyruvates/metabolism
MH  - Rats
MH  - Rats, Inbred Strains
MH  - Time Factors
MH  - Triglycerides/metabolism
MH  - Weight Gain
OID - NASA: 89276321
EDAT- 1989/01/01 00:00
MHDA- 1989/01/01 00:01
CRDT- 1989/01/01 00:00
PHST- 1989/01/01 00:00 [pubmed]
PHST- 1989/01/01 00:01 [medline]
PHST- 1989/01/01 00:00 [entrez]
AID - 10.1007/BF00418503 [doi]
PST - ppublish
SO  - Eur J Appl Physiol Occup Physiol. 1989;58(6):583-90. doi: 10.1007/BF00418503.