PMID- 27325300
OWN - NLM
STAT- MEDLINE
DCOM- 20170710
LR  - 20220408
IS  - 1435-5922 (Electronic)
IS  - 0944-1174 (Linking)
VI  - 51
IP  - 8
DP  - 2016 Aug
TI  - Evidence-based clinical practice guidelines for gastroesophageal reflux disease 
      2015.
PG  - 751-67
LID - 10.1007/s00535-016-1227-8 [doi]
AB  - As an increase in gastroesophageal reflux disease (GERD) has been reported in 
      Japan, and public interest in GERD has been increasing, the Japanese Society of 
      Gastroenterology published the Evidence-based Clinical Practice Guidelines for 
      GERD (1st edition) in 2009. Six years have passed since its publication, and 
      there have been a large number of reports in Japan concerning the epidemiology, 
      pathophysiology, treatment, and Barrett's esophagus during this period. By 
      incorporating the contents of these reports, the guidelines were completely 
      revised, and a new edition was published in October 2015. The revised edition 
      consists of eight items: epidemiology, pathophysiology, diagnosis, internal 
      treatment, surgical treatment, esophagitis after surgery of the upper 
      gastrointestinal tract, extraesophageal symptoms, and Barrett's esophagus. This 
      paper summarizes these guidelines, particularly the parts related to the 
      treatment for GERD. In the present revision, aggressive proton pump inhibitor 
      (PPI) maintenance therapy is recommended for severe erosive GERD, and on-demand 
      therapy or continuous maintenance therapy is recommended for mild erosive GERD or 
      PPI-responsive non-erosive GERD. Moreover, PPI-resistant GERD (insufficient 
      symptomatic improvement and/or esophageal mucosal break persisting despite the 
      administration of PPI at a standard dose for 8 weeks) is defined, and a 
      standard-dose PPI twice a day, change in PPI, change in the PPI timing of dosing, 
      addition of a prokinetic drug, addition of rikkunshito (traditional Japanese 
      herbal medicine), and addition of histamine H2-receptor antagonist are 
      recommended for its treatment. If no improvement is observed even after these 
      treatments, pathophysiological evaluation with esophageal impedance-pH monitoring 
      or esophageal manometry at an expert facility for diseases of the esophagus is 
      recommended.
FAU - Iwakiri, Katsuhiko
AU  - Iwakiri K
AD  - Department of Gastroenterology, Nippon Medical School Graduate School of 
      Medicine, Sendagi 1-1-5, Bunkyo-ku, Tokyo, 113-8603, Japan. k-iwa@nms.ac.jp.
AD  - Guidelines Committee for Creating and Evaluating the "Evidence-based Clinical 
      Practice Guidelines for Gastroesophageal Reflux Disease", the Japanese Society of 
      Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, 
      Japan. k-iwa@nms.ac.jp.
FAU - Kinoshita, Yoshikazu
AU  - Kinoshita Y
AD  - Guidelines Committee for Creating and Evaluating the "Evidence-based Clinical 
      Practice Guidelines for Gastroesophageal Reflux Disease", the Japanese Society of 
      Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, 
      Japan.
FAU - Habu, Yasuki
AU  - Habu Y
AD  - Guidelines Committee for Creating and Evaluating the "Evidence-based Clinical 
      Practice Guidelines for Gastroesophageal Reflux Disease", the Japanese Society of 
      Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, 
      Japan.
FAU - Oshima, Tadayuki
AU  - Oshima T
AD  - Guidelines Committee for Creating and Evaluating the "Evidence-based Clinical 
      Practice Guidelines for Gastroesophageal Reflux Disease", the Japanese Society of 
      Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, 
      Japan.
FAU - Manabe, Noriaki
AU  - Manabe N
AD  - Guidelines Committee for Creating and Evaluating the "Evidence-based Clinical 
      Practice Guidelines for Gastroesophageal Reflux Disease", the Japanese Society of 
      Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, 
      Japan.
FAU - Fujiwara, Yasuhiro
AU  - Fujiwara Y
AD  - Guidelines Committee for Creating and Evaluating the "Evidence-based Clinical 
      Practice Guidelines for Gastroesophageal Reflux Disease", the Japanese Society of 
      Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, 
      Japan.
FAU - Nagahara, Akihito
AU  - Nagahara A
AD  - Guidelines Committee for Creating and Evaluating the "Evidence-based Clinical 
      Practice Guidelines for Gastroesophageal Reflux Disease", the Japanese Society of 
      Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, 
      Japan.
FAU - Kawamura, Osamu
AU  - Kawamura O
AD  - Guidelines Committee for Creating and Evaluating the "Evidence-based Clinical 
      Practice Guidelines for Gastroesophageal Reflux Disease", the Japanese Society of 
      Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, 
      Japan.
FAU - Iwakiri, Ryuichi
AU  - Iwakiri R
AD  - Guidelines Committee for Creating and Evaluating the "Evidence-based Clinical 
      Practice Guidelines for Gastroesophageal Reflux Disease", the Japanese Society of 
      Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, 
      Japan.
FAU - Ozawa, Soji
AU  - Ozawa S
AD  - Guidelines Committee for Creating and Evaluating the "Evidence-based Clinical 
      Practice Guidelines for Gastroesophageal Reflux Disease", the Japanese Society of 
      Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, 
      Japan.
FAU - Ashida, Kiyoshi
AU  - Ashida K
AD  - Guidelines Committee for Creating and Evaluating the "Evidence-based Clinical 
      Practice Guidelines for Gastroesophageal Reflux Disease", the Japanese Society of 
      Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, 
      Japan.
FAU - Ohara, Shuichi
AU  - Ohara S
AD  - Guidelines Committee for Creating and Evaluating the "Evidence-based Clinical 
      Practice Guidelines for Gastroesophageal Reflux Disease", the Japanese Society of 
      Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, 
      Japan.
FAU - Kashiwagi, Hideyuki
AU  - Kashiwagi H
AD  - Guidelines Committee for Creating and Evaluating the "Evidence-based Clinical 
      Practice Guidelines for Gastroesophageal Reflux Disease", the Japanese Society of 
      Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, 
      Japan.
FAU - Adachi, Kyoichi
AU  - Adachi K
AD  - Guidelines Committee for Creating and Evaluating the "Evidence-based Clinical 
      Practice Guidelines for Gastroesophageal Reflux Disease", the Japanese Society of 
      Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, 
      Japan.
FAU - Higuchi, Kazuhide
AU  - Higuchi K
AD  - Guidelines Committee for Creating and Evaluating the "Evidence-based Clinical 
      Practice Guidelines for Gastroesophageal Reflux Disease", the Japanese Society of 
      Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, 
      Japan.
FAU - Miwa, Hiroto
AU  - Miwa H
AD  - Guidelines Committee for Creating and Evaluating the "Evidence-based Clinical 
      Practice Guidelines for Gastroesophageal Reflux Disease", the Japanese Society of 
      Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, 
      Japan.
FAU - Fujimoto, Kazuma
AU  - Fujimoto K
AD  - Guidelines Committee for Creating and Evaluating the "Evidence-based Clinical 
      Practice Guidelines for Gastroesophageal Reflux Disease", the Japanese Society of 
      Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, 
      Japan.
FAU - Kusano, Motoyasu
AU  - Kusano M
AD  - Guidelines Committee for Creating and Evaluating the "Evidence-based Clinical 
      Practice Guidelines for Gastroesophageal Reflux Disease", the Japanese Society of 
      Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, 
      Japan.
FAU - Hoshihara, Yoshio
AU  - Hoshihara Y
AD  - Guidelines Committee for Creating and Evaluating the "Evidence-based Clinical 
      Practice Guidelines for Gastroesophageal Reflux Disease", the Japanese Society of 
      Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, 
      Japan.
FAU - Kawano, Tatsuyuki
AU  - Kawano T
AD  - Guidelines Committee for Creating and Evaluating the "Evidence-based Clinical 
      Practice Guidelines for Gastroesophageal Reflux Disease", the Japanese Society of 
      Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, 
      Japan.
FAU - Haruma, Ken
AU  - Haruma K
AD  - Guidelines Committee for Creating and Evaluating the "Evidence-based Clinical 
      Practice Guidelines for Gastroesophageal Reflux Disease", the Japanese Society of 
      Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, 
      Japan.
FAU - Hongo, Michio
AU  - Hongo M
AD  - Guidelines Committee for Creating and Evaluating the "Evidence-based Clinical 
      Practice Guidelines for Gastroesophageal Reflux Disease", the Japanese Society of 
      Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, 
      Japan.
FAU - Sugano, Kentaro
AU  - Sugano K
AD  - Guidelines Committee for Creating and Evaluating the "Evidence-based Clinical 
      Practice Guidelines for Gastroesophageal Reflux Disease", the Japanese Society of 
      Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, 
      Japan.
FAU - Watanabe, Mamoru
AU  - Watanabe M
AD  - Guidelines Committee for Creating and Evaluating the "Evidence-based Clinical 
      Practice Guidelines for Gastroesophageal Reflux Disease", the Japanese Society of 
      Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, 
      Japan.
FAU - Shimosegawa, Tooru
AU  - Shimosegawa T
AD  - Guidelines Committee for Creating and Evaluating the "Evidence-based Clinical 
      Practice Guidelines for Gastroesophageal Reflux Disease", the Japanese Society of 
      Gastroenterology (JSGE), K-18 Building 8F, 8-9-13, Ginza, Chuo, Tokyo, 104-0061, 
      Japan.
LA  - eng
PT  - Journal Article
PT  - Practice Guideline
PT  - Review
DEP - 20160621
PL  - Japan
TA  - J Gastroenterol
JT  - Journal of gastroenterology
JID - 9430794
RN  - 0 (Alginates)
RN  - 0 (Antacids)
RN  - 0 (Hexuronic Acids)
RN  - 0 (Proton Pump Inhibitors)
RN  - 8A5D83Q4RW (Glucuronic Acid)
SB  - IM
MH  - Alginates/therapeutic use
MH  - Algorithms
MH  - Antacids/therapeutic use
MH  - Barrett Esophagus/etiology
MH  - Evidence-Based Medicine/methods
MH  - Gastroesophageal Reflux/complications/diagnosis/epidemiology/*therapy
MH  - Glucuronic Acid/therapeutic use
MH  - Hexuronic Acids/therapeutic use
MH  - Humans
MH  - Life Style
MH  - Proton Pump Inhibitors/therapeutic use
OTO - NOTNLM
OT  - Algorithm
OT  - Gastroesophageal reflux disease (GERD)
OT  - Guideline
OT  - Heartburn
OT  - Japanese traditional medicine
OT  - Non-erosive reflux disease
OT  - Prokinetic drug
OT  - Proton pump inhibitor
OT  - Reflux esophagitis
EDAT- 2016/06/22 06:00
MHDA- 2017/07/14 06:00
CRDT- 2016/06/22 06:00
PHST- 2016/05/16 00:00 [received]
PHST- 2016/05/17 00:00 [accepted]
PHST- 2016/06/22 06:00 [entrez]
PHST- 2016/06/22 06:00 [pubmed]
PHST- 2017/07/14 06:00 [medline]
AID - 10.1007/s00535-016-1227-8 [pii]
AID - 10.1007/s00535-016-1227-8 [doi]
PST - ppublish
SO  - J Gastroenterol. 2016 Aug;51(8):751-67. doi: 10.1007/s00535-016-1227-8. Epub 2016 
      Jun 21.