PMID- 27330401 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20160622 LR - 20201001 IS - 1340-3516 (Print) IS - 1347-7501 (Electronic) IS - 1340-3516 (Linking) VI - 27 IP - 2 DP - 2016 TI - Oxidative stress markers in Thoroughbred horses after castration surgery under inhalation anesthesia. PG - 77-9 LID - 10.1294/jes.27.77 [doi] AB - Oxidative stress has been reported to occur during surgery. It is important to reduce intraoperative oxidative stress to improve the postoperative prognosis. However, there are no reports regarding oxidative stress related to surgery in horses. In the present study, we measured pre and postsurgical diacron-reactive oxygen metabolites (d-ROMs) and biological antioxidant potential (BAP); the oxidative stress index (OSI) was then calculated (OSI=d-ROMs/BAP x 100). d-ROMs were not significantly different between the pre and postsurgical periods. However, BAP significantly decreased after surgery (P=0.02), and OSI significantly increased after surgery (P=0.02). Based on these results, it suggested that castration surgery under inhalation anesthesia decreases the antioxidant potential and causes oxidative stress in horses. FAU - Tsuzuki, Nao AU - Tsuzuki N AD - Laboratory of Veterinary Surgery, Faculty of Agriculture, University of Miyazaki, Miyazaki 889-2192, Japan. FAU - Sasaki, Naoki AU - Sasaki N AD - Department of Clinical Veterinary Science, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido 080-8555, Japan. FAU - Kusano, Kanichi AU - Kusano K AD - Japan Racing Association Miho Training Center, Ibaraki 300-0493, Japan. FAU - Endo, Yoshiro AU - Endo Y AD - Japan Racing Association Miyazaki Yearling Training Farm, Miyazaki 880-0036, Japan. FAU - Torisu, Shidow AU - Torisu S AD - Veterinary Teaching Hospital, Faculty of Agriculture, University of Miyazaki, Miyazaki 889-2192, Japan. LA - eng PT - Journal Article DEP - 20160621 PL - Japan TA - J Equine Sci JT - Journal of equine science JID - 9503751 PMC - PMC4914400 OTO - NOTNLM OT - Thoroughbred OT - oxidative stress OT - surgery EDAT- 2016/06/23 06:00 MHDA- 2016/06/23 06:01 PMCR- 2016/01/01 CRDT- 2016/06/23 06:00 PHST- 2015/10/05 00:00 [received] PHST- 2016/04/06 00:00 [accepted] PHST- 2016/06/23 06:00 [entrez] PHST- 2016/06/23 06:00 [pubmed] PHST- 2016/06/23 06:01 [medline] PHST- 2016/01/01 00:00 [pmc-release] AID - 1526 [pii] AID - 10.1294/jes.27.77 [doi] PST - ppublish SO - J Equine Sci. 2016;27(2):77-9. doi: 10.1294/jes.27.77. Epub 2016 Jun 21.