PMID- 27330531
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160622
LR  - 20201001
IS  - 1611-2156 (Print)
IS  - 1611-2156 (Electronic)
IS  - 1611-2156 (Linking)
VI  - 15
DP  - 2016
TI  - Sensitivity of clinical isolates of Candida to essential oils from Burseraceae 
      family.
PG  - 280-9
LID - 10.17179/excli2014-621 [doi]
AB  - The aim of this study was to investigate the chemical composition and antifungal 
      activity of four commercial essential oils from the Burseraceae family - two 
      Boswellia carterii Flueck oils, Canarium luzonicum (Blume) A. Gray oil, and 
      Commiphora myrrha (Nees) Engl oil, against most common Candida spp. recovered 
      from the human oral cavity. The essential oil samples were analyzed by GC-FID and 
      GC/MS. The analysis showed that major essential oils' components were alpha-pinene 
      (23.04 % and 31.84 %), limonene (45.62 %) and curzerene (34.65 %), respectively. 
      Minimum inhibitory (MIC) and minimum fungicidal (MFC) concentrations were 
      determined using a microdilution standardized technique. All tested Candida spp. 
      clinical isolates and ATCC strains showed susceptibility to tested essential oils 
      in a dose dependent manner. The strongest antifungal activity was shown by 
      essential oil of B. carterii, sample 2; the average MIC values ranged from 1.25 
      to 1.34 mg/ml, and MFC values ranged from 2.50 to 3.75 mg/ml, depending on the 
      fungus. This study supports the possible use of essential oils from the 
      Bursecaceae family in reduction and elimination of Candida spp. populations in 
      patients with oral cavity fungal infections.
FAU - Nikolic, Milos
AU  - Nikolic M
AD  - Institute for Biological Research "Sinisa Stankovic", University of Belgrade, 
      Bulevar Despota Stefana 142, 11000, Belgrade, Serbia.
FAU - Smiljkovic, Marija
AU  - Smiljkovic M
AD  - Institute for Biological Research "Sinisa Stankovic", University of Belgrade, 
      Bulevar Despota Stefana 142, 11000, Belgrade, Serbia.
FAU - Markovic, Tatjana
AU  - Markovic T
AD  - Institute for Medicinal Plant Research "Josif Pancic", Tadeusa Koscuska 2, 11000 
      Belgrade, Serbia.
FAU - Cirica, Ana
AU  - Cirica A
AD  - Institute for Biological Research "Sinisa Stankovic", University of Belgrade, 
      Bulevar Despota Stefana 142, 11000, Belgrade, Serbia.
FAU - Glamoclija, Jasmina
AU  - Glamoclija J
AD  - Institute for Biological Research "Sinisa Stankovic", University of Belgrade, 
      Bulevar Despota Stefana 142, 11000, Belgrade, Serbia.
FAU - Markovic, Dejan
AU  - Markovic D
AD  - Faculty of Dental Medicine, Department of Pediatric and Preventive Dentistry, 
      University of Belgrade, dr Subotica 8, 11000 Belgrade, Serbia.
FAU - Sokovic, Marina
AU  - Sokovic M
AD  - Institute for Biological Research "Sinisa Stankovic", University of Belgrade, 
      Bulevar Despota Stefana 142, 11000, Belgrade, Serbia.
LA  - eng
PT  - Journal Article
DEP - 20160419
PL  - Germany
TA  - EXCLI J
JT  - EXCLI journal
JID - 101299402
PMC - PMC4908663
OTO - NOTNLM
OT  - Burseraceae
OT  - Candida spp.
OT  - essential oils
OT  - oral candidosis
OT  - susceptibility
EDAT- 2016/06/23 06:00
MHDA- 2016/06/23 06:01
PMCR- 2016/04/19
CRDT- 2016/06/23 06:00
PHST- 2014/10/02 00:00 [received]
PHST- 2014/12/13 00:00 [accepted]
PHST- 2016/06/23 06:00 [entrez]
PHST- 2016/06/23 06:00 [pubmed]
PHST- 2016/06/23 06:01 [medline]
PHST- 2016/04/19 00:00 [pmc-release]
AID - 2014-621 [pii]
AID - Doc280 [pii]
AID - 10.17179/excli2014-621 [doi]
PST - epublish
SO  - EXCLI J. 2016 Apr 19;15:280-9. doi: 10.17179/excli2014-621. eCollection 2016.