PMID- 27330941
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160622
LR  - 20200930
IS  - 2211-7539 (Print)
IS  - 2211-7539 (Electronic)
IS  - 2211-7539 (Linking)
VI  - 7
DP  - 2015 Mar
TI  - Successful treatment of Cryptococcus neoformans immune reconstitution 
      inflammatory syndrome in an immunocompetent host using thalidomide.
PG  - 12-4
LID - 10.1016/j.mmcr.2014.12.003 [doi]
AB  - Immune reconstitution inflammatory syndrome (IRIS) can complicate antifungal 
      treatment of cryptococcosis. There are limited data on managing 
      cryptococcal-associated IRIS. We describe an immunocompetent patient who 
      developed IRIS complicating Cryptococcus neoformans meningitis, successfully 
      treated with thalidomide following failure of corticosteroid therapy. Data on 
      thalidomide use in cryptococcal IRIS are awaited.
FAU - Somerville, Lucy K
AU  - Somerville LK
AD  - Centre for Infectious Diseases and Microbiology Laboratory Services, Level 3 
      Institute of Clinical Pathology and Medical Research, Westmead Hospital, 
      Westmead, New South Wales 2145, Australia.
FAU - Henderson, Andrew P
AU  - Henderson AP
AD  - Department of Neurology, Westmead Hospital, Westmead, New South Wales, Australia.
FAU - Chen, Sharon C A
AU  - Chen SC
AD  - Centre for Infectious Diseases and Microbiology Laboratory Services, Level 3 
      Institute of Clinical Pathology and Medical Research, Westmead Hospital, 
      Westmead, New South Wales 2145, Australia; Marie Bashir Institute for Infectious 
      Diseases and Biosecurity, University of Sydney, Westmead Hospital, Westmead, New 
      South Wales, Australia.
FAU - Kok, Jen
AU  - Kok J
AD  - Centre for Infectious Diseases and Microbiology Laboratory Services, Level 3 
      Institute of Clinical Pathology and Medical Research, Westmead Hospital, 
      Westmead, New South Wales 2145, Australia; Marie Bashir Institute for Infectious 
      Diseases and Biosecurity, University of Sydney, Westmead Hospital, Westmead, New 
      South Wales, Australia; Centre for Research Excellence in Critical Infections, 
      University of Sydney, Westmead Hospital, Westmead, New South Wales, Australia.
LA  - eng
PT  - Journal Article
DEP - 20141220
PL  - Netherlands
TA  - Med Mycol Case Rep
JT  - Medical mycology case reports
JID - 101598259
PMC - PMC4909863
OTO - NOTNLM
OT  - Cryptococcus neoformans
OT  - Immune reconstitution
OT  - Thalidomide
EDAT- 2015/03/01 00:00
MHDA- 2015/03/01 00:01
PMCR- 2014/12/20
CRDT- 2016/06/23 06:00
PHST- 2014/11/23 00:00 [received]
PHST- 2014/12/19 00:00 [accepted]
PHST- 2016/06/23 06:00 [entrez]
PHST- 2015/03/01 00:00 [pubmed]
PHST- 2015/03/01 00:01 [medline]
PHST- 2014/12/20 00:00 [pmc-release]
AID - S2211-7539(14)00055-4 [pii]
AID - 10.1016/j.mmcr.2014.12.003 [doi]
PST - epublish
SO  - Med Mycol Case Rep. 2014 Dec 20;7:12-4. doi: 10.1016/j.mmcr.2014.12.003. 
      eCollection 2015 Mar.