PMID- 27331112 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20160622 LR - 20200930 IS - 2352-3409 (Print) IS - 2352-3409 (Electronic) IS - 2352-3409 (Linking) VI - 8 DP - 2016 Sep TI - Proteomic dataset for altered glycoprotein expression upon GALNT3 knockdown in ovarian cancer cells. PG - 342-9 LID - 10.1016/j.dib.2016.05.060 [doi] AB - This article contains raw and processed data related to research published in "Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation" [1]. The data presented here was obtained with the application of a bioorthogonal chemical reporter strategy analyzing differential glycoprotein expression following the knock-down (KD) of the GALNT3 gene in the epithelial ovarian cancer (EOC) cell line A2780s. LC-MS/MS mass spectrometry analysis was then performed and the processed data related to the identified glycoproteins show that several hundred proteins are differentially expressed between control and GALNT3 KD A2780s cells. The obtained data also uncover numerous novel glycoproteins; some of which could represent new potential EOC biomarkers and/or therapeutic targets. FAU - Sheta, Razan AU - Sheta R AD - Department of Molecular Medicine, Laval University, Quebec PQ, Canada; Centre de recherche du CHU de Quebec, L'Hotel-Dieu de Quebec, Quebec PQ, Canada. FAU - Roux-Dalvai, Florence AU - Roux-Dalvai F AD - Centre de recherche du CHU de Quebec, CHUL, Quebec PQ, Canada. FAU - Woo, Christina M AU - Woo CM AD - Department of Chemistry, Stanford University, Stanford, CA, USA. FAU - Fournier, Frederic AU - Fournier F AD - Centre de recherche du CHU de Quebec, CHUL, Quebec PQ, Canada. FAU - Bourassa, Sylvie AU - Bourassa S AD - Centre de recherche du CHU de Quebec, CHUL, Quebec PQ, Canada. FAU - Bertozzi, Carolyn R AU - Bertozzi CR AD - Department of Chemistry, Stanford University, Stanford, CA, USA; Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA. FAU - Droit, Arnaud AU - Droit A AD - Department of Molecular Medicine, Laval University, Quebec PQ, Canada; Centre de recherche du CHU de Quebec, CHUL, Quebec PQ, Canada. FAU - Bachvarov, Dimcho AU - Bachvarov D AD - Department of Molecular Medicine, Laval University, Quebec PQ, Canada; Centre de recherche du CHU de Quebec, L'Hotel-Dieu de Quebec, Quebec PQ, Canada. LA - eng GR - R01 CA200423/CA/NCI NIH HHS/United States PT - Journal Article DEP - 20160530 PL - Netherlands TA - Data Brief JT - Data in brief JID - 101654995 PMC - PMC4908283 OTO - NOTNLM OT - Ac4GalNAz labeling OT - GALNT3 OT - Glycoproteomics OT - Glycosylation OT - Label free quantification OT - NetOGlyc and NetNGlyc prediction analysis EDAT- 2016/06/23 06:00 MHDA- 2016/06/23 06:01 PMCR- 2016/05/30 CRDT- 2016/06/23 06:00 PHST- 2016/04/19 00:00 [received] PHST- 2016/05/12 00:00 [revised] PHST- 2016/05/24 00:00 [accepted] PHST- 2016/06/23 06:00 [entrez] PHST- 2016/06/23 06:00 [pubmed] PHST- 2016/06/23 06:01 [medline] PHST- 2016/05/30 00:00 [pmc-release] AID - S2352-3409(16)30348-1 [pii] AID - 10.1016/j.dib.2016.05.060 [doi] PST - epublish SO - Data Brief. 2016 May 30;8:342-9. doi: 10.1016/j.dib.2016.05.060. eCollection 2016 Sep.