PMID- 27338026 OWN - NLM STAT- MEDLINE DCOM- 20180419 LR - 20181202 IS - 1557-3117 (Electronic) IS - 1053-2498 (Linking) VI - 35 IP - 7 DP - 2016 Jul TI - Incorporating human leukocyte antibody results into clinical practice. PG - 851-6 LID - S1053-2498(16)30135-8 [pii] LID - 10.1016/j.healun.2016.05.010 [doi] AB - The use of human leukocyte antigen (HLA) antibody testing by solid-phase assay has improved both the specificity and sensitivity of HLA antibody detection. It did, however, introduce questions regarding interpretation of crossmatch results in light of these additional data. Herein we provide a clinician's and a laboratory professional's perspective on incorporating HLA results into clinical practice. We strongly encourage fostering ongoing dialog between the two disciplines to develop appropriate, specific guidelines. CI - Copyright (c) 2016 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved. FAU - Tambur, Anat R AU - Tambur AR AD - Transplant Immunology Laboratory, Comprehensive Transplant Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA. Electronic address: a-tambur@northwestern.edu. FAU - Lavee, Jacob AU - Lavee J AD - Heart Transplantation Unit, Department of Cardiac Surgery, Leviev Heart Center, Sheba Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. LA - eng PT - Editorial DEP - 20160520 PL - United States TA - J Heart Lung Transplant JT - The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation JID - 9102703 RN - 0 (Antibodies) RN - 0 (HLA Antigens) RN - 0 (Isoantibodies) SB - IM MH - Antibodies MH - HLA Antigens MH - Histocompatibility Testing MH - Humans MH - Isoantibodies MH - *Leukocytes MH - Sensitivity and Specificity OTO - NOTNLM OT - HLA antibodies OT - donor specific antibodies OT - heart transplantation OT - solid-phase assays OT - virtual crossmatch EDAT- 2016/06/25 06:00 MHDA- 2018/04/20 06:00 CRDT- 2016/06/25 06:00 PHST- 2015/12/10 00:00 [received] PHST- 2016/03/23 00:00 [revised] PHST- 2016/05/12 00:00 [accepted] PHST- 2016/06/25 06:00 [entrez] PHST- 2016/06/25 06:00 [pubmed] PHST- 2018/04/20 06:00 [medline] AID - S1053-2498(16)30135-8 [pii] AID - 10.1016/j.healun.2016.05.010 [doi] PST - ppublish SO - J Heart Lung Transplant. 2016 Jul;35(7):851-6. doi: 10.1016/j.healun.2016.05.010. Epub 2016 May 20.