PMID- 27338274
OWN - NLM
STAT- MEDLINE
DCOM- 20170314
LR  - 20220316
IS  - 1613-2246 (Electronic)
IS  - 0021-5155 (Linking)
VI  - 60
IP  - 5
DP  - 2016 Sep
TI  - Asymmetrical steepening of the foveal contour after macular hole surgery with 
      internal limiting membrane peeling.
PG  - 388-94
LID - 10.1007/s10384-016-0460-2 [doi]
AB  - PURPOSE: We have previously shown that the thickness of the parafoveal retina was 
      asymmetrical in spectral-domain optical coherence tomographic (SD-OCT) images 
      after idiopathic macular hole (MH) closure by pars plana vitrectomy (PPV) with 
      internal limiting membrane (ILM) peeling. The aim of this study was to determine 
      whether the foveal slopes around the closed MH were also asymmetrical. METHODS: 
      Forty-three eyes with an MH treated with PPV with ILM peeling at Matsumoto Dental 
      University Hospital were studied. The foveal slope was determined with ImageJ 
      software in both the horizontal and vertical images obtained by SD-OCT at 
      6 months after the surgery. The possible related factors were also compared. 
      RESULTS: The mean angles of the foveal slopes of the nasal, superior, inferior, 
      and temporal sectors were 31.4 degrees  +/- 6.2 degrees , 31.2 degrees  +/- 5.4 degrees , 31.6 degrees  +/- 7.4 degrees , and 
      29.9 degrees  +/- 6.6 degrees , respectively, in the fellow eyes. The corresponding values in the 
      operated eyes were significantly steeper at 50.4 degrees  +/- 9.1 degrees , 46.9 degrees  +/- 11.3 degrees , 
      48.6 degrees  +/- 11.3 degrees , and 41.3 degrees  +/- 11.2 degrees , respectively (P < 0.00001). Both the nasal and 
      inferior slopes were significantly steeper than the temporal slopes of the same 
      operated eye (P = 0.002 and P = 0.023, respectively). There was no significant 
      correlation between each slope and the visual acuity, MH size, area of peeled 
      ILM, postoperative parafoveal retinal thickness, defect of the retinal outer 
      layers, disc-foveal distance, stage, and use of dye for ILM peeling. CONCLUSIONS: 
      Although the postoperative foveal contour was markedly changed asymmetrically, 
      the significance of the change was not determined.
FAU - Ohta, Kouichi
AU  - Ohta K
AD  - Department of Ophthalmology, Matsumoto Dental University, 1780 Gobara, Hirooka, 
      Shiojiri, Nagano, 399-0781, Japan. ohta@po.mdu.ac.jp.
FAU - Sato, Atsuko
AU  - Sato A
AD  - Department of Ophthalmology, Matsumoto Dental University, 1780 Gobara, Hirooka, 
      Shiojiri, Nagano, 399-0781, Japan.
FAU - Senda, Nami
AU  - Senda N
AD  - Department of Ophthalmology, Matsumoto Dental University, 1780 Gobara, Hirooka, 
      Shiojiri, Nagano, 399-0781, Japan.
FAU - Fukui, Emi
AU  - Fukui E
AD  - Department of Ophthalmology, Matsumoto Dental University, 1780 Gobara, Hirooka, 
      Shiojiri, Nagano, 399-0781, Japan.
LA  - eng
PT  - Journal Article
DEP - 20160623
PL  - Japan
TA  - Jpn J Ophthalmol
JT  - Japanese journal of ophthalmology
JID - 0044652
SB  - IM
MH  - Aged
MH  - Basement Membrane/diagnostic imaging/*surgery
MH  - Female
MH  - Follow-Up Studies
MH  - Fovea Centralis/*diagnostic imaging
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Postoperative Period
MH  - Retinal Perforations/diagnosis/*surgery
MH  - Retrospective Studies
MH  - Tomography, Optical Coherence/*methods
MH  - Visual Acuity
MH  - Vitrectomy/*methods
OTO - NOTNLM
OT  - Foveal contour
OT  - Idiopathic macular hole
OT  - Internal limiting membrane
OT  - Vitrectomy
EDAT- 2016/06/25 06:00
MHDA- 2017/03/16 06:00
CRDT- 2016/06/25 06:00
PHST- 2016/01/11 00:00 [received]
PHST- 2016/05/20 00:00 [accepted]
PHST- 2016/06/25 06:00 [entrez]
PHST- 2016/06/25 06:00 [pubmed]
PHST- 2017/03/16 06:00 [medline]
AID - 10.1007/s10384-016-0460-2 [pii]
AID - 10.1007/s10384-016-0460-2 [doi]
PST - ppublish
SO  - Jpn J Ophthalmol. 2016 Sep;60(5):388-94. doi: 10.1007/s10384-016-0460-2. Epub 
      2016 Jun 23.