PMID- 27338467 OWN - NLM STAT- MEDLINE DCOM- 20170309 LR - 20221207 IS - 2072-6643 (Electronic) IS - 2072-6643 (Linking) VI - 8 IP - 6 DP - 2016 Jun 21 TI - Effect of Improving Dietary Quality on Arterial Stiffness in Subjects with Type 1 and Type 2 Diabetes: A 12 Months Randomised Controlled Trial. LID - 10.3390/nu8060382 [doi] LID - 382 AB - People with diabetes have accelerated arterial stiffening. The aim of this study was to determine the effect of increasing fruit, vegetable and dairy intake for 12 months on carotid femoral pulse wave velocity (cfPWV), augmentation index (AIx), and central blood pressure (cBP), compared to a usual diet control, in people with type 1 and type 2 diabetes. In a 12 months randomised controlled trial, cfPWV, AIx and cBP were measured every 3 months. The intervention group received dietary counselling to increase consumption of fruit (+1 serving/day; 150 g/day), vegetables (+2 servings/day; 150 g/day) and dairy (+1 serving/day; 200-250 g/day) at baseline, 1, 3, 6 and 9 months. The control group continued on their usual diet. One hundred and nine participants were randomised and 92 (intervention n = 45; control n = 47) completed. At 3 months, fruit (184 g/day; p = 0.001) and dairy (83 g/day; p = 0.037) intake increased in the intervention group compared with the control group but this increase was not maintained at 12 months. After adjustment for baseline measurements there was no time by treatment effect for central systolic or diastolic BP, AIx or cfPWV. A time effect existed for AIx which modestly increased over time. Peripheral diastolic BP and central pulse pressure were improved in the intervention group compared with the control group at 12 months. In the cohort with type 1 and type 2 diabetes, improving dietary quality by increasing consumption of fruit, vegetables and dairy did not improve cBP, AIx or cfPWV, compared with a control group continuing on their usual diet, after 12 months. FAU - Petersen, Kristina S AU - Petersen KS AD - School of Pharmacy and Medical Sciences & Sansom Institute for Health Research, University of South Australia, GPO Box 2471, Adelaide SA 5000, Australia. kristina.petersen@mymail.unisa.edu.au. FAU - Clifton, Peter M AU - Clifton PM AD - School of Pharmacy and Medical Sciences & Sansom Institute for Health Research, University of South Australia, GPO Box 2471, Adelaide SA 5000, Australia. peter.clifton@unisa.edu.au. FAU - Lister, Natalie AU - Lister N AD - School of Pharmacy and Medical Sciences & Sansom Institute for Health Research, University of South Australia, GPO Box 2471, Adelaide SA 5000, Australia. natalie.blanch@mymail.unisa.edu.au. FAU - Keogh, Jennifer B AU - Keogh JB AD - School of Pharmacy and Medical Sciences & Sansom Institute for Health Research, University of South Australia, GPO Box 2471, Adelaide SA 5000, Australia. jennifer.keogh@unisa.edu.au. LA - eng PT - Journal Article PT - Randomized Controlled Trial DEP - 20160621 PL - Switzerland TA - Nutrients JT - Nutrients JID - 101521595 RN - 0 (Blood Glucose) RN - 0 (Glycated Hemoglobin A) RN - 0 (Triglycerides) RN - 9007-41-4 (C-Reactive Protein) RN - 97C5T2UQ7J (Cholesterol) RN - 9NEZ333N27 (Sodium) RN - AYI8EX34EU (Creatinine) RN - RWP5GA015D (Potassium) SB - IM MH - Aged MH - Blood Glucose/metabolism MH - Blood Pressure MH - Body Mass Index MH - C-Reactive Protein/metabolism MH - Cholesterol/blood MH - Creatinine/urine MH - Dairy Products MH - Diabetes Mellitus, Type 1/blood/*diet therapy MH - Diabetes Mellitus, Type 2/blood/*diet therapy MH - *Diet MH - Female MH - Fruit MH - Glycated Hemoglobin/metabolism MH - Humans MH - Male MH - Middle Aged MH - Patient Compliance MH - Potassium/urine MH - Pulse Wave Analysis MH - Sodium/urine MH - Triglycerides/blood MH - *Vascular Stiffness MH - Vegetables PMC - PMC4924222 OTO - NOTNLM OT - arterial stiffness OT - augmentation index OT - central blood pressure OT - diabetes OT - diet OT - nutrition OT - pulse wave velocity EDAT- 2016/06/25 06:00 MHDA- 2017/03/10 06:00 PMCR- 2016/06/01 CRDT- 2016/06/25 06:00 PHST- 2016/04/19 00:00 [received] PHST- 2016/05/30 00:00 [revised] PHST- 2016/06/15 00:00 [accepted] PHST- 2016/06/25 06:00 [entrez] PHST- 2016/06/25 06:00 [pubmed] PHST- 2017/03/10 06:00 [medline] PHST- 2016/06/01 00:00 [pmc-release] AID - nu8060382 [pii] AID - nutrients-08-00382 [pii] AID - 10.3390/nu8060382 [doi] PST - epublish SO - Nutrients. 2016 Jun 21;8(6):382. doi: 10.3390/nu8060382.