PMID- 27339469 OWN - NLM STAT- MEDLINE DCOM- 20171116 LR - 20220330 IS - 1872-8332 (Electronic) IS - 0169-5002 (Linking) VI - 107 DP - 2017 May TI - Possible applications of circulating tumor cells in patients with non small cell lung cancer. PG - 59-64 LID - S0169-5002(16)30349-X [pii] LID - 10.1016/j.lungcan.2016.05.027 [doi] AB - Recent experiences indicate that, as already reported for other types of cancer, circulating tumor cells (CTCs) may play a role also in non small cell lung cancer (NSCLC) for diagnosis, therapy monitoring and prognostic purposes. CTCs evaluation could be particularly relevant in this clinical setting not only for the objective difficulty in obtaining tumor tissue, but also because of the lack of reliable tumor markers. In the current review, we will focus on the possible applications of CTCs in NSCLC patients. CI - Copyright (c) 2016 Elsevier Ireland Ltd. All rights reserved. FAU - Tartarone, Alfredo AU - Tartarone A AD - Department of Onco-Hematology, Division of Medical Oncology, Centro di Riferimento Oncologico della Basilicata, IRCCS, Rionero in Vulture (PZ), Italy. Electronic address: tarta1@virgilio.it. FAU - Rossi, Elisabetta AU - Rossi E AD - Department of Surgery, Oncology and Gastroenterology, Oncology Section, University of Padova, Padova, Italy. FAU - Lerose, Rosa AU - Lerose R AD - Hospital Pharmacy, Centro di Riferimento Oncologico della Basilicata, IRCCS, Rionero in Vulture (PZ), Italy. FAU - Mambella, Giuseppina AU - Mambella G AD - Department of Onco-Hematology, Division of Medical Oncology, Centro di Riferimento Oncologico della Basilicata, IRCCS, Rionero in Vulture (PZ), Italy. FAU - Calderone, Giuseppe AU - Calderone G AD - Department of Onco-Hematology, Division of Medical Oncology, Centro di Riferimento Oncologico della Basilicata, IRCCS, Rionero in Vulture (PZ), Italy. FAU - Zamarchi, Rita AU - Zamarchi R AD - Istituto Oncologico Veneto IRCCS, Padova, Italy. FAU - Aieta, Michele AU - Aieta M AD - Department of Onco-Hematology, Division of Medical Oncology, Centro di Riferimento Oncologico della Basilicata, IRCCS, Rionero in Vulture (PZ), Italy. LA - eng PT - Journal Article PT - Review DEP - 20160531 PL - Ireland TA - Lung Cancer JT - Lung cancer (Amsterdam, Netherlands) JID - 8800805 RN - 0 (Biomarkers, Tumor) RN - EC 2.7.10.1 (ALK protein, human) RN - EC 2.7.10.1 (Anaplastic Lymphoma Kinase) RN - EC 2.7.10.1 (ErbB Receptors) RN - EC 2.7.10.1 (Receptor Protein-Tyrosine Kinases) SB - IM MH - Anaplastic Lymphoma Kinase MH - Biomarkers, Tumor/blood/*metabolism MH - Carcinoma, Non-Small-Cell Lung/blood/*pathology/therapy MH - Cell Count MH - Clinical Decision-Making MH - ErbB Receptors/genetics MH - Humans MH - Liquid Biopsy MH - Lung Neoplasms/blood/*pathology MH - Mutation MH - Neoplastic Cells, Circulating/metabolism/*pathology MH - Prognosis MH - Receptor Protein-Tyrosine Kinases OTO - NOTNLM OT - Anaplastic lymphoma kinase fusion gene OT - Circulating tumor cells OT - Epidermal growth factor receptor OT - Liquid biopsy OT - Non small cell lung cancer EDAT- 2016/06/25 06:00 MHDA- 2017/11/29 06:00 CRDT- 2016/06/25 06:00 PHST- 2016/03/01 00:00 [received] PHST- 2016/05/01 00:00 [revised] PHST- 2016/05/29 00:00 [accepted] PHST- 2016/06/25 06:00 [pubmed] PHST- 2017/11/29 06:00 [medline] PHST- 2016/06/25 06:00 [entrez] AID - S0169-5002(16)30349-X [pii] AID - 10.1016/j.lungcan.2016.05.027 [doi] PST - ppublish SO - Lung Cancer. 2017 May;107:59-64. doi: 10.1016/j.lungcan.2016.05.027. Epub 2016 May 31.