PMID- 27344558
OWN - NLM
STAT- MEDLINE
DCOM- 20161221
LR  - 20181202
IS  - 1573-2959 (Electronic)
IS  - 0167-6369 (Linking)
VI  - 188
IP  - 7
DP  - 2016 Jul
TI  - Determination of steroidal oestrogens in tap water samples using solid-phase 
      extraction on a molecularly imprinted polymer sorbent and quantification with gas 
      chromatography-mass spectrometry (GC-MS).
PG  - 433
LID - 10.1007/s10661-016-5435-8 [doi]
AB  - An analytical method was established and validated for the analysis of steroidal 
      oestrogens in tap water samples. Gas chromatography coupled to high-resolution 
      mass spectrometry (GC-HRMS) and gas chromatography coupled to tandem mass 
      spectrometry (GC-MS/MS) were used for the identification/quantification of 
      selected compounds and the analytical performance of these techniques was 
      evaluated. Liquid-liquid extraction (LLE) and solid-phase extraction (SPE) with a 
      molecularly imprinted polymer (MIP) stationary phase that was highly selective 
      for oestrogens were used for the extraction of 100-mL aliquots of water samples. 
      The recoveries of analytes with the described methods ranged from 92 to 114 %, 
      while the repeatability in terms of relative standard deviations (RSDs) was in 
      the range from 2.1 to 15.2 % (n = 5). It was concluded that SPE with MIP that was 
      highly selective for oestrogens in combination with GC-HRMS detection is more 
      preferable for the analysis of oestrogens in tap water samples. The typical 
      oestrogen, 17beta-estradiol (17beta-E2), was detected above the method limit of 
      quantification (m-LOQ) in 5 of 14 analysed tap water samples at concentrations 
      from 0.09 to 0.15 ng L(-1). Despite that 17alpha-ethynylestradiol (17alpha-EE2) was not 
      quantified in this study above m-LOQ, the presence of this chemical was 
      qualitatively confirmed in some of the analysed samples.
FAU - Zacs, D
AU  - Zacs D
AD  - Department of Chemistry, University of Latvia, Jelgavas iela 1, Riga, LV-1004, 
      Latvia. dzintars.zachs@gmail.com.
FAU - Perkons, I
AU  - Perkons I
AD  - Department of Chemistry, University of Latvia, Jelgavas iela 1, Riga, LV-1004, 
      Latvia.
FAU - Bartkevics, V
AU  - Bartkevics V
AD  - Department of Chemistry, University of Latvia, Jelgavas iela 1, Riga, LV-1004, 
      Latvia.
LA  - eng
PT  - Journal Article
DEP - 20160625
PL  - Netherlands
TA  - Environ Monit Assess
JT  - Environmental monitoring and assessment
JID - 8508350
RN  - 0 (Drinking Water)
RN  - 0 (Estrogens)
RN  - 0 (Polymers)
RN  - 0 (Water Pollutants, Chemical)
RN  - 423D2T571U (Ethinyl Estradiol)
SB  - IM
MH  - Chromatography, Gas
MH  - Drinking Water/*chemistry
MH  - Environmental Monitoring/*methods
MH  - Estrogens/*analysis
MH  - Ethinyl Estradiol/*analysis
MH  - Gas Chromatography-Mass Spectrometry/methods
MH  - Limit of Detection
MH  - Liquid-Liquid Extraction/methods
MH  - Molecular Imprinting
MH  - Polymers/*chemistry
MH  - Solid Phase Extraction/methods
MH  - Tandem Mass Spectrometry/methods
MH  - Water Pollutants, Chemical/*analysis
OTO - NOTNLM
OT  - Gas chromatography-high-resolution mass spectrometry
OT  - Gas chromatography-tandem mass spectrometry
OT  - Molecularly imprinted polymer
OT  - Solid-phase extraction
OT  - Steroidal oestrogens
EDAT- 2016/06/28 06:00
MHDA- 2016/12/22 06:00
CRDT- 2016/06/27 06:00
PHST- 2016/02/27 00:00 [received]
PHST- 2016/06/14 00:00 [accepted]
PHST- 2016/06/27 06:00 [entrez]
PHST- 2016/06/28 06:00 [pubmed]
PHST- 2016/12/22 06:00 [medline]
AID - 10.1007/s10661-016-5435-8 [pii]
AID - 10.1007/s10661-016-5435-8 [doi]
PST - ppublish
SO  - Environ Monit Assess. 2016 Jul;188(7):433. doi: 10.1007/s10661-016-5435-8. Epub 
      2016 Jun 25.