PMID- 27345339
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20180517
LR  - 20180517
IS  - 1473-0189 (Electronic)
IS  - 1473-0189 (Linking)
VI  - 16
IP  - 14
DP  - 2016 Jul 5
TI  - A reconfigurable continuous-flow fluidic routing fabric using a modular, scalable 
      primitive.
PG  - 2730-41
LID - 10.1039/c6lc00477f [doi]
AB  - Microfluidic devices, by definition, are required to move liquids from one 
      physical location to another. Given a finite and frequently fixed set of physical 
      channels to route fluids, a primitive design element that allows reconfigurable 
      routing of that fluid from any of n input ports to any n output ports will 
      dramatically change the paradigms by which these chips are designed and applied. 
      Furthermore, if these elements are "regular" regarding their design, the 
      programming and fabrication of these elements becomes scalable. This paper 
      presents such a design element called a transposer. We illustrate the design, 
      fabrication and operation of a single transposer. We then scale this design to 
      create a programmable fabric towards a general-purpose, reconfigurable 
      microfluidic platform analogous to the Field Programmable Gate Array (FPGA) found 
      in digital electronics.
FAU - Silva, Ryan
AU  - Silva R
AD  - Boston University Department of Electrical and Computer Engineering, 8 Saint 
      Mary's St., Boston, USA. rjsilva@bu.edu dougd@bu.edu and Biological Design 
      Center, 610 Commonwealth Avenue, Boston, USA.
FAU - Bhatia, Swapnil
AU  - Bhatia S
AD  - Boston University Department of Electrical and Computer Engineering, 8 Saint 
      Mary's St., Boston, USA. rjsilva@bu.edu dougd@bu.edu and Biological Design 
      Center, 610 Commonwealth Avenue, Boston, USA.
FAU - Densmore, Douglas
AU  - Densmore D
AD  - Boston University Department of Electrical and Computer Engineering, 8 Saint 
      Mary's St., Boston, USA. rjsilva@bu.edu dougd@bu.edu and Biological Design 
      Center, 610 Commonwealth Avenue, Boston, USA.
LA  - eng
PT  - Journal Article
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PL  - England
TA  - Lab Chip
JT  - Lab on a chip
JID - 101128948
EDAT- 2016/06/28 06:00
MHDA- 2016/06/28 06:01
CRDT- 2016/06/28 06:00
PHST- 2016/06/28 06:00 [entrez]
PHST- 2016/06/28 06:00 [pubmed]
PHST- 2016/06/28 06:01 [medline]
AID - 10.1039/c6lc00477f [doi]
PST - ppublish
SO  - Lab Chip. 2016 Jul 5;16(14):2730-41. doi: 10.1039/c6lc00477f.