PMID- 27347666 OWN - NLM STAT- MEDLINE DCOM- 20180118 LR - 20180118 IS - 1521-3765 (Electronic) IS - 0947-6539 (Linking) VI - 22 IP - 32 DP - 2016 Aug 1 TI - One-Step Synthesis of Silver Nanoparticle-Decorated Hydroxyapatite Nanowires for the Construction of Highly Flexible Free-Standing Paper with High Antibacterial Activity. PG - 11224-31 LID - 10.1002/chem.201601438 [doi] AB - A highly flexible and free-standing paper with high antibacterial activity made from silver nanoparticle (AgNP)-decorated ultralong hydroxyapatite nanowires (HAPNWs) is reported. The HAPNWs@AgNPs nanocomposites were obtained from a facile one-step solvothermal process and utilized for the construction of highly flexible and free-standing inorganic paper through a simple vacuum-filtration procedure. The structure and properties of the HAPNWs@AgNPs paper were characterized in detail. Scanning electron microscope (SEM) and transmission electron microscope (TEM) micrographs show that AgNPs are highly dispersed and stabilized in the nanocomposite and exhibit a narrow particle size distribution. The effects of the concentration of silver nitrate, solvothermal temperature and time on the product were systematically investigated. This method is simple, convenient and reproducible. The as-prepared HAPNWs@AgNPs paper shows long-time sustained silver-ion release, high antibacterial activity against both Gram-negative and Gram-positive bacteria, and good biocompatibility. Overall, this work provides a novel pathway for the preparation of a new type of highly flexible, free-standing and antibacterial inorganic paper made from silver nanoparticle-decorated hydroxyapatite nanowires for various applications, as a promising functional biomaterial. CI - (c) 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. FAU - Xiong, Zhi-Chao AU - Xiong ZC AD - State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, P. R. China. FAU - Zhu, Ying-Jie AU - Zhu YJ AD - State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, P. R. China. y.j.zhu@mail.sic.ac.cn. FAU - Chen, Fei-Fei AU - Chen FF AD - State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, P. R. China. FAU - Sun, Tuan-Wei AU - Sun TW AD - State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, P. R. China. FAU - Shen, Yue-Qin AU - Shen YQ AD - State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, P. R. China. LA - eng PT - Journal Article DEP - 20160627 PL - Germany TA - Chemistry JT - Chemistry (Weinheim an der Bergstrasse, Germany) JID - 9513783 RN - 0 (Anti-Bacterial Agents) RN - 3M4G523W1G (Silver) RN - 91D9GV0Z28 (Durapatite) SB - IM MH - Anti-Bacterial Agents/*chemical synthesis/chemistry MH - Durapatite/*chemical synthesis/*chemistry MH - Gram-Positive Bacteria MH - Metal Nanoparticles/*chemistry MH - Microscopy, Electron, Transmission MH - Nanocomposites/*chemistry MH - Nanowires/*chemistry MH - Silver/*chemistry OTO - NOTNLM OT - free-standing paper OT - hydroxyapatite OT - nanoparticles OT - nanowires OT - silver EDAT- 2016/06/28 06:00 MHDA- 2018/01/19 06:00 CRDT- 2016/06/28 06:00 PHST- 2016/03/27 00:00 [received] PHST- 2016/06/28 06:00 [entrez] PHST- 2016/06/28 06:00 [pubmed] PHST- 2018/01/19 06:00 [medline] AID - 10.1002/chem.201601438 [doi] PST - ppublish SO - Chemistry. 2016 Aug 1;22(32):11224-31. doi: 10.1002/chem.201601438. Epub 2016 Jun 27.