PMID- 27348163
OWN - NLM
STAT- MEDLINE
DCOM- 20170323
LR  - 20181202
IS  - 1512-0112 (Print)
IS  - 1512-0112 (Linking)
IP  - 254
DP  - 2016 May
TI  - HEMATOLOGICAL MARKERS OF THE NO-REFLOW PHENOMEN ON IN-PATIENTS UNDERGOING PRIMARY 
      PERCUTANEOUS CORONARY INTERVENTION.
PG  - 26-32
AB  - The study aims to investigate hematological parameters of the no-reflow 
      phenomenon (NRP) developed in patients underwent primary percutaneous coronary 
      intervention (pPCI) due to diagnosis of ST elevation myocardial infarction 
      (STEMI). The study sample consisted of a total of 90 patients, of which 44 
      patients who underwent pPCI and developed NRP without anemia and chronic renal 
      failure (mean age was 64; 34 males and 10 females) were included in the 
      experimental group, and the control group consisted of 46 patients with normal 
      reperfusion flow (mean age was 58; 34 males and 12 females). In both groups, Red 
      blood-cell Distribution Width (RDW), Mean Platelet Volume (MPV), plateletcrit 
      (PCT), Platelet Distribution Width (PDW), and neutrophil count were observed. The 
      demographic characteristics of both groups were similar, except the higher mean 
      age of the experimental group (age; 64.0+/-12.6; 58.0+/-12.5). No correlation was 
      found between development of no-reflow and incidence of risk factors such as 
      hypertension, diabetes mellitus, dyslipidemia, smoking, family history and 
      gender. In the no-reflow group, RDW level (16.2%+/-2.1; 14.2%+/-0.7, p<0.001), MPV 
      level (7.9+/-1.2; 7.3+/-0.8, p<0.05), PDW level (18.1+/-1.2; 17.4+/-1.2, p<0.05), PCT 
      level (0.2+/-0.06 vs 0.17+/-0.05) and neutrophil count (9.9+/-3.7; 7.1+/-3.3, p<0.001) 
      was found to be higher than the control group. According to logistic regression 
      analysis, RDW (OR; 23.4, <95% Cl 4.6-118.9, p<0.001), PDW (OR; 2.8, <95% Cl 
      1.2-6.4, p<0.05) and neutrophil count (OR; 1.4, Cl 1.1-1.9, p<0.05) were found to 
      be the predictors of NRP development. Hemogram is a cheap and easy to apply test. 
      In our study, a relationship between the NRP development and RDW, PDW, MPV, PCT, 
      and neutrophil counts was found in patients who underwent pPCI. At the same time, 
      RDW, PDW, and the neutrophil count were found to be predictors of no-reflow 
      development.
FAU - Sahinkus, S
AU  - Sahinkus S
AD  - Sakarya University, Department of Cardiology; Findikli State Hospital, Department 
      of Internal Medicine, Rize; Dr. Siyami Ersek Thoracic and Cardiovascular Surgery 
      Training and Research Hospital, Cardiology Department, Istanbul, Turkey.
FAU - Cakar, M
AU  - Cakar M
AD  - Sakarya University, Department of Cardiology; Findikli State Hospital, Department 
      of Internal Medicine, Rize; Dr. Siyami Ersek Thoracic and Cardiovascular Surgery 
      Training and Research Hospital, Cardiology Department, Istanbul, Turkey.
FAU - Yaylaci, S
AU  - Yaylaci S
AD  - Sakarya University, Department of Cardiology; Findikli State Hospital, Department 
      of Internal Medicine, Rize; Dr. Siyami Ersek Thoracic and Cardiovascular Surgery 
      Training and Research Hospital, Cardiology Department, Istanbul, Turkey.
FAU - Aydin, E
AU  - Aydin E
AD  - Sakarya University, Department of Cardiology; Findikli State Hospital, Department 
      of Internal Medicine, Rize; Dr. Siyami Ersek Thoracic and Cardiovascular Surgery 
      Training and Research Hospital, Cardiology Department, Istanbul, Turkey.
FAU - Can, Y
AU  - Can Y
AD  - Sakarya University, Department of Cardiology; Findikli State Hospital, Department 
      of Internal Medicine, Rize; Dr. Siyami Ersek Thoracic and Cardiovascular Surgery 
      Training and Research Hospital, Cardiology Department, Istanbul, Turkey.
FAU - Kocayigit, I
AU  - Kocayigit I
AD  - Sakarya University, Department of Cardiology; Findikli State Hospital, Department 
      of Internal Medicine, Rize; Dr. Siyami Ersek Thoracic and Cardiovascular Surgery 
      Training and Research Hospital, Cardiology Department, Istanbul, Turkey.
FAU - Osken, A
AU  - Osken A
AD  - Sakarya University, Department of Cardiology; Findikli State Hospital, Department 
      of Internal Medicine, Rize; Dr. Siyami Ersek Thoracic and Cardiovascular Surgery 
      Training and Research Hospital, Cardiology Department, Istanbul, Turkey.
FAU - Akdemir, R
AU  - Akdemir R
AD  - Sakarya University, Department of Cardiology; Findikli State Hospital, Department 
      of Internal Medicine, Rize; Dr. Siyami Ersek Thoracic and Cardiovascular Surgery 
      Training and Research Hospital, Cardiology Department, Istanbul, Turkey.
FAU - Gunduz, H
AU  - Gunduz H
AD  - Sakarya University, Department of Cardiology; Findikli State Hospital, Department 
      of Internal Medicine, Rize; Dr. Siyami Ersek Thoracic and Cardiovascular Surgery 
      Training and Research Hospital, Cardiology Department, Istanbul, Turkey.
LA  - eng
PT  - Journal Article
PL  - Georgia (Republic)
TA  - Georgian Med News
JT  - Georgian medical news
JID - 101218222
SB  - IM
MH  - Aged
MH  - Blood Platelets/pathology
MH  - Case-Control Studies
MH  - Coronary Circulation
MH  - Erythrocyte Count
MH  - Female
MH  - Humans
MH  - Male
MH  - Mean Platelet Volume
MH  - Middle Aged
MH  - Myocardial Infarction/blood/*physiopathology/therapy
MH  - Neutrophils/pathology
MH  - No-Reflow Phenomenon/*blood/etiology/physiopathology
MH  - Percutaneous Coronary Intervention/*adverse effects
EDAT- 2016/06/28 06:00
MHDA- 2017/03/24 06:00
CRDT- 2016/06/28 06:00
PHST- 2016/06/28 06:00 [entrez]
PHST- 2016/06/28 06:00 [pubmed]
PHST- 2017/03/24 06:00 [medline]
PST - ppublish
SO  - Georgian Med News. 2016 May;(254):26-32.