PMID- 27348757
OWN - NLM
STAT- MEDLINE
DCOM- 20170221
LR  - 20170817
IS  - 2374-4243 (Electronic)
IS  - 2374-4243 (Linking)
VI  - 48
IP  - 10
DP  - 2016 Oct
TI  - Molecular events by which dendritic cells promote Th2 immune protection in 
      helmith infection.
PG  - 715-20
LID - 10.1080/23744235.2016.1194529 [doi]
AB  - Helminth parasites are a major cause of global infectious diseases, affecting 
      nearly one quarter of the world's population. The common feature of helminth 
      infections is to skew the immune system towards a T-helper 2 (Th2) response that 
      helps to control disease. Dendritic cells (DCs), which are professional 
      antigen-presenting cells, play a critical role for Th2 skewing against helminth 
      parasites. However, the molecular mechanisms by which helminth antigens activate 
      DCs for Th2 polarization have not yet been clearly defined. This review provides 
      a focused update on the major role of DCs for inducing and/or enhancing Th2 
      immune responses in helminthic infection and will discuss the main 
      signalling-dependent and independent mechanisms by which helminth antigens 
      activate DCs for Th2 skewing.
FAU - Mendez-Samperio, Patricia
AU  - Mendez-Samperio P
AD  - a Departamento de Inmunologia, Escuela Nacional de Ciencias Biologicas, IPN , 
      Prol. Carpio y Plan de Ayala , CDMexico , Mexico.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20160627
PL  - England
TA  - Infect Dis (Lond)
JT  - Infectious diseases (London, England)
JID - 101650235
RN  - 0 (Antigens, Helminth)
SB  - IM
MH  - Antigens, Helminth/*immunology
MH  - Dendritic Cells/*immunology
MH  - Helminthiasis/*immunology
MH  - Humans
MH  - Th2 Cells/*immunology
OTO - NOTNLM
OT  - Dendritic cells
OT  - helminths
OT  - type-2 response
EDAT- 2016/06/28 06:00
MHDA- 2017/02/22 06:00
CRDT- 2016/06/28 06:00
PHST- 2016/06/28 06:00 [entrez]
PHST- 2016/06/28 06:00 [pubmed]
PHST- 2017/02/22 06:00 [medline]
AID - 10.1080/23744235.2016.1194529 [doi]
PST - ppublish
SO  - Infect Dis (Lond). 2016 Oct;48(10):715-20. doi: 10.1080/23744235.2016.1194529. 
      Epub 2016 Jun 27.