PMID- 27352275
OWN - NLM
STAT- MEDLINE
DCOM- 20171207
LR  - 20180330
IS  - 1524-4040 (Electronic)
IS  - 0148-396X (Linking)
VI  - 80
IP  - 3
DP  - 2017 Mar 1
TI  - Assessment of the Minimum Clinically Important Difference in the Timed Up and Go 
      Test After Surgery for Lumbar Degenerative Disc Disease.
PG  - 380-385
LID - 10.1227/NEU.0000000000001320 [doi]
AB  - BACKGROUND: The Timed Up and Go Test (TUG Test) has previously been described as 
      a reliable tool to evaluate objective functional impairment in patients with 
      degenerative disc disease. OBJECTIVE: The aim of this study was to assess the 
      minimum clinically important difference (MCID) of the TUG Test. METHODS: The TUG 
      Test (measured in seconds) was correlated with validated patient-reported outcome 
      measures (PROs) of pain intensity (Visual Analog Scale for back and leg pain), 
      functional impairment (Oswestry Disability Index, Roland Morris Disability 
      Index), and health-related quality of life measures (Short Form-12 and EuroQol 
      5D). Three established methods were used to establish anchor-based MCID values 
      using responders of the following PROs (Visual Analog Scale back and leg pain, 
      Oswestry Disability Index, Roland Morris Disability Index, EuroQol 5D index, and 
      Short Form-12 Physical Component Summary) as anchors: (1) average change, (2) 
      minimum detectable change, and (3) change difference approach. RESULTS: One 
      hundred patients with a mean +/- SD age of 56.2 +/- 16.1 years, 57 (57%) male, 45 
      patients undergoing microdiscectomy, 35 undergoing lumbar decompression, and 20 
      undergoing fusion surgery were studied. The 3 MCID computation methods revealed a 
      range of MCID values according to the PRO used from 0.9 s (Oswestry Disability 
      Index based on the change difference approach) to 6.0 s (EuroQol 5D index based 
      on the minimum detectable change approach), with a mean MCID of 3.4 s for all 
      measured PROs. CONCLUSION: The MCID for the TUG Test time is highly variable 
      depending on the computation technique used. The average TUG Test MCID was 3.4 s 
      using all 3 methods and all anchors.
CI  - Copyright (c) 2017 by the Congress of Neurological Surgeons
FAU - Gautschi, Oliver P
AU  - Gautschi OP
AD  - Department of Neurosurgery and Fac-ulty of Medicine, University Hospital Geneva, 
      Geneva, Switzerland.
FAU - Stienen, Martin N
AU  - Stienen MN
AD  - Department of Neurosurgery and Fac-ulty of Medicine, University Hospital Geneva, 
      Geneva, Switzerland.
FAU - Corniola, Marco V
AU  - Corniola MV
AD  - Department of Neurosurgery and Fac-ulty of Medicine, University Hospital Geneva, 
      Geneva, Switzerland.
FAU - Joswig, Holger
AU  - Joswig H
AD  - Depart-ment of Neurosurgery, Cantonal Hospital St. Gallen, St. Gallen, 
      Switzerland.
FAU - Schaller, Karl
AU  - Schaller K
AD  - Department of Neurosurgery and Fac-ulty of Medicine, University Hospital Geneva, 
      Geneva, Switzerland.
FAU - Hildebrandt, Gerhard
AU  - Hildebrandt G
AD  - Depart-ment of Neurosurgery, Cantonal Hospital St. Gallen, St. Gallen, 
      Switzerland.
FAU - Smoll, Nicolas R
AU  - Smoll NR
AD  - School of Medicine and Public Health, University of Newcastle, Newcastle, New 
      South Wales, Australia.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Neurosurgery
JT  - Neurosurgery
JID - 7802914
SB  - IM
MH  - Adult
MH  - Aged
MH  - *Decompression, Surgical
MH  - *Disability Evaluation
MH  - Disabled Persons
MH  - *Diskectomy
MH  - Female
MH  - Humans
MH  - Intervertebral Disc Degeneration/*surgery
MH  - Lumbar Vertebrae/surgery
MH  - Male
MH  - Middle Aged
MH  - Pain Measurement/methods
MH  - *Quality of Life
MH  - Treatment Outcome
MH  - Visual Analog Scale
OTO - NOTNLM
OT  - Degenerative disc disease
OT  - Low back pain
OT  - Lumbar spine surgery
OT  - MCID
OT  - Objective outcome measurement
OT  - Postoperative outcome
OT  - Timed Up and Go Test
EDAT- 2016/06/29 06:00
MHDA- 2017/12/08 06:00
CRDT- 2016/06/29 06:00
PHST- 2015/11/24 00:00 [received]
PHST- 2016/04/08 00:00 [accepted]
PHST- 2016/06/29 06:00 [pubmed]
PHST- 2017/12/08 06:00 [medline]
PHST- 2016/06/29 06:00 [entrez]
AID - 10.1227/NEU.0000000000001320 [doi]
PST - ppublish
SO  - Neurosurgery. 2017 Mar 1;80(3):380-385. doi: 10.1227/NEU.0000000000001320.