PMID- 27353336
OWN - NLM
STAT- MEDLINE
DCOM- 20171213
LR  - 20180403
IS  - 1600-0897 (Electronic)
IS  - 1046-7408 (Linking)
VI  - 76
IP  - 3
DP  - 2016 Sep
TI  - The role of dendritic cells in male reproductive tract.
PG  - 186-92
LID - 10.1111/aji.12536 [doi]
AB  - Dendritic cells (DCs) are the most potent professional antigen-presenting cells. 
      The central role of various DC subsets as bridges between innate and adaptive 
      immunity has become more and more evident. However, the role of DC subsets in 
      male reproductive tract remains largely unexplored, in particular distinct DC 
      subsets (including myeloid and plasmacytoid DCs), their maturation stage, and 
      tissue distribution, as well as state of health or disease. Furthermore, 
      infection and inflammation of male genital tract are thought to be a primary 
      etiological factor of male infertility. This review sheds some light on this 
      complex and rapidly growing field. It summarized the recent findings and deals 
      with the characterization and role of DCs in male reproductive tract, that is, 
      testis, epididymis, prostate, seminal vesicle, semen, and foreskin, which might 
      help to understand the immunopathological mechanisms of male infertility and 
      design effective vaccines for male reproductive health.
CI  - (c) 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
FAU - Wang, Peng
AU  - Wang P
AD  - Department of Urology, Daping Hospital, Institute of Surgery Research, The Third 
      Military Medical University, Chongqing, China.
FAU - Duan, Yong-Gang
AU  - Duan YG
AD  - Centre of Reproductive Medicine and Andrology, The First Affiliated Hospital of 
      Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20160629
PL  - Denmark
TA  - Am J Reprod Immunol
JT  - American journal of reproductive immunology (New York, N.Y. : 1989)
JID - 8912860
SB  - IM
MH  - Animals
MH  - Dendritic Cells/*immunology/pathology
MH  - Genitalia, Male/*immunology/pathology
MH  - Humans
MH  - Infertility, Male/*immunology/pathology
MH  - Male
MH  - Reproductive Health
OTO - NOTNLM
OT  - dendritic cells
OT  - epididymis
OT  - male infertility
OT  - prostate
OT  - semen
OT  - testis
EDAT- 2016/06/30 06:00
MHDA- 2017/12/14 06:00
CRDT- 2016/06/30 06:00
PHST- 2016/04/23 00:00 [received]
PHST- 2016/06/10 00:00 [accepted]
PHST- 2016/06/30 06:00 [entrez]
PHST- 2016/06/30 06:00 [pubmed]
PHST- 2017/12/14 06:00 [medline]
AID - 10.1111/aji.12536 [doi]
PST - ppublish
SO  - Am J Reprod Immunol. 2016 Sep;76(3):186-92. doi: 10.1111/aji.12536. Epub 2016 Jun 
      29.