PMID- 27356791
OWN - NLM
STAT- MEDLINE
DCOM- 20170329
LR  - 20191210
IS  - 0376-2491 (Print)
IS  - 0376-2491 (Linking)
VI  - 96
IP  - 23
DP  - 2016 Jun 21
TI  - [Effect of standardized treatment on reactivity of toe microcirculation in 
      patients with type 2 diabetes mellitus].
PG  - 1826-9
LID - 10.3760/cma.j.issn.0376-2491.2016.23.008 [doi]
AB  - OBJECTIVE: To evaluate the effect of standardized treatment on reactivity of the 
      lower limb terminal microcirculation in patients with type 2 diabetes mellitus 
      (T2DM) by high frequency ultrasound combined with warm bath. METHODS: A total of 
      66 patients with T2DM were collected from June 2014 to May 2015 in the Second 
      Affiliated Hospital of Wenzhou Medical University.According to the vascular 
      complications , the patients were divided into group A without complications (36 
      cases)and group B with complications (30 cases). Hemodynamic parameters such as 
      peak systolic velocity(PSV), end-diastolic velocity(EDV) and resistance index(RI) 
      of the right plantar digital artery on fibular side of the 1st toe were acquired 
      through Doppler in all subjects.Then the above operation were performed 
      repetitively on all subjects after the right foot was immersed in 40 ℃ warm water 
      for 5 minutes.The change rates of PSV, EDV and RI were calculated after warm 
      bath.All subjects were examined again after three months treatment .The growth 
      rates of the change rate of PSV, EDV and RI were calculated after treatment.All 
      parameters were analyzed. RESULTS: The change rates of the parameters in group B 
      before and after treatment were lower than those of group A, before treatment 
      (0.108+/-0.077 vs 0.184+/-0.091, P=0.037, 0.184+/-0.101 vs 0.380+/-0.167, P=0.002, 
      0.007+/-0.004 vs 0.015+/-0.008, P=0.028 7), after treatment (0.155+/-0.111 vs 
      0.421+/-0.138, 0.287+/-0.108 vs 0.794+/-0.286, 0.012+/-0.008 vs 0.039+/-0.014, P=0.000); 
      the post treatment growth rates of the change rates of the parameters in group B 
      were all less than those of group A (0.414+/-0.303 vs 2.192+/-2.673, P=0.048, 
      0.660+/-0.406 vs 1.422+/-1.075, P=0.042, 0.633+/-0.830 vs 2.191+/-2.269, P=0.048). The 
      change rates of the parameters in two groups after treatment were higher than 
      those before treatment (all P<0.05). CONCLUSION: Warm bath test can be used to 
      detect change degree of hemodynamic parameters in patients with T2DM so as to 
      evaluate reactivity of blood microcirculation, which has a certain clinical 
      application value in treatment.
FAU - Li, X Y
AU  - Li XY
AD  - Department of Ultrasound, Second Affiliated Hospital of Wenzhou Medical 
      University, Wenzhou 325027, China.
FAU - Jiao, Y
AU  - Jiao Y
FAU - Zhou, X L
AU  - Zhou XL
FAU - Yang, Y
AU  - Yang Y
FAU - Zhao, Y P
AU  - Zhao YP
FAU - Zheng, C
AU  - Zheng C
FAU - Zou, C P
AU  - Zou CP
LA  - chi
PT  - Evaluation Study
PT  - Journal Article
PL  - China
TA  - Zhonghua Yi Xue Za Zhi
JT  - Zhonghua yi xue za zhi
JID - 7511141
SB  - IM
MH  - Blood Flow Velocity
MH  - Diabetes Mellitus, Type 2/blood/*physiopathology
MH  - Hemodynamics
MH  - Humans
MH  - *Microcirculation
MH  - Toes/*blood supply
MH  - Ultrasonography, Doppler, Pulsed
MH  - *Ultrasonography, Interventional
EDAT- 2016/07/01 06:00
MHDA- 2017/03/31 06:00
CRDT- 2016/07/01 06:00
PHST- 2016/07/01 06:00 [entrez]
PHST- 2016/07/01 06:00 [pubmed]
PHST- 2017/03/31 06:00 [medline]
AID - 10.3760/cma.j.issn.0376-2491.2016.23.008 [doi]
PST - ppublish
SO  - Zhonghua Yi Xue Za Zhi. 2016 Jun 21;96(23):1826-9. doi: 
      10.3760/cma.j.issn.0376-2491.2016.23.008.