PMID- 27358705 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20160630 LR - 20200930 IS - 1975-4612 (Print) IS - 2005-9655 (Electronic) IS - 1975-4612 (Linking) VI - 24 IP - 2 DP - 2016 Jun TI - Echocardiographic Predictors for Left Ventricular Remodeling after Acute ST Elevation Myocardial Infarction with Low Risk Group: Speckle Tracking Analysis. PG - 128-34 LID - 10.4250/jcu.2016.24.2.128 [doi] AB - BACKGROUND: We sought to assess echocardiographic predictors of left ventricular (LV) adverse remodeling after successfully reperfused acute ST elevation myocardial infarction (STEMI). LV remodeling is commonly found in STEMI patients and it may suggest adverse outcome in acute myocardial infarction. We sought to identify whether 2D strain and torsion be independent parameters for prediction of LV adverse remodeling. METHODS: We investigated 208 patients with low-risk STEMI patients who had follow up echocardiography at 6 or more months. After clinical assessments, all patients received revascularization according to current guideline. LV remodeling was defined as > 20% increase in end-diastolic volume (EDV) at follow up. RESULTS: During the follow-up (11.9 +/- 5.3 months), 53 patients (25.5%) showed LV remodeling. In univariate analysis, EDV, end-systolic volume, deceleration time (DT), CK-MB, and global longitudinal strain (GLS) were associated with LV remodeling. In multivariate analysis, EDV [hazard ratio (HR): 0.922, 95% confidence interval (CI): 0.897-0.948, p< 0.001], GLS (HR: 0.842, 95% CI: 0.728-0.974, p = 0.020), DT (HR: 0.989, 95% CI: 0.980-0.998, p = 0.023) and CK-MB (HR: 1.003, 95% CI: 1.000-1.005, p = 0.033) independently predicted LV remodeling. However, global circumferential strain, net twist, and twist or untwist rate were not associated with remodeling. CONCLUSION: Of various parameters of speckle strain, only GLS predicted adverse remodeling in STEMI patients. FAU - Na, Hyun-Min AU - Na HM AD - College of Medicine, Seoul National University, Seoul, Korea. FAU - Cho, Goo-Yeong AU - Cho GY AD - Cardiovascular Center, Seoul National University Bundang Hospital, Seongnam, Korea. FAU - Lee, Joo Myung AU - Lee JM AD - Cardiovascular Center, Seoul National University Hospital, Seoul, Korea. FAU - Cha, Myung-Jin AU - Cha MJ AD - Cardiovascular Center, Seoul National University Hospital, Seoul, Korea. FAU - Yoon, Yeonyee E AU - Yoon YE AD - Cardiovascular Center, Seoul National University Bundang Hospital, Seongnam, Korea. FAU - Lee, Seung-Pyo AU - Lee SP AD - Cardiovascular Center, Seoul National University Hospital, Seoul, Korea. FAU - Kim, Hyung-Kwan AU - Kim HK AD - Cardiovascular Center, Seoul National University Hospital, Seoul, Korea. FAU - Kim, Yong-Jin AU - Kim YJ AD - Cardiovascular Center, Seoul National University Hospital, Seoul, Korea. FAU - Sohn, Dae-Won AU - Sohn DW AD - Cardiovascular Center, Seoul National University Hospital, Seoul, Korea. LA - eng PT - Journal Article DEP - 20160622 PL - Korea (South) TA - J Cardiovasc Ultrasound JT - Journal of cardiovascular ultrasound JID - 101477138 PMC - PMC4925390 OTO - NOTNLM OT - Acute myocardial infarction OT - Remodeling OT - Strain EDAT- 2016/07/01 06:00 MHDA- 2016/07/01 06:01 PMCR- 2016/06/01 CRDT- 2016/07/01 06:00 PHST- 2016/01/18 00:00 [received] PHST- 2016/04/21 00:00 [revised] PHST- 2016/05/10 00:00 [accepted] PHST- 2016/07/01 06:00 [entrez] PHST- 2016/07/01 06:00 [pubmed] PHST- 2016/07/01 06:01 [medline] PHST- 2016/06/01 00:00 [pmc-release] AID - 10.4250/jcu.2016.24.2.128 [doi] PST - ppublish SO - J Cardiovasc Ultrasound. 2016 Jun;24(2):128-34. doi: 10.4250/jcu.2016.24.2.128. Epub 2016 Jun 22.