PMID- 27362467 OWN - NLM STAT- MEDLINE DCOM- 20171204 LR - 20220310 IS - 1460-2202 (Electronic) IS - 0271-3683 (Linking) VI - 42 IP - 2 DP - 2017 Feb TI - Correlation of Vitreomacular Traction with Foveal Thickness, Subfoveal Choroidal Thickness, and Vitreomacular/Foveal Angle. PG - 297-301 LID - 10.1080/02713683.2016.1175020 [doi] AB - PURPOSE: To investigate the structure of vitreomacular traction (VMT), specifically, if a correlation exists between 1) the VMT type/grade and the central foveal thickness (CFT) and subfoveal and adjacent choroidal thickness, 2) the vitreomacular/foveal angle (VMFA) and the CFT and subfoveal and adjacent choroidal thickness, and 3) the diameter of vitreomacular adhesion (VMA) and CFT and subfoveal and adjacent choroidal thickness. MATERIALS AND METHODS: Retrospective, multicenter image analysis study. We analyzed raster scans of the macula taken with spectral-domain optical coherence tomography (SD-OCT) of 61 eyes of 55 patients with VMT. Conventional scans of the vitreoretinal interface were analyzed to measure CFT and the degree of VMFA. Enhanced depth imaging (EDI) scans were analyzed to measure the choroidal thickness in the macula. The multivariate test of means and the t-test were used for statistical comparisons. RESULTS: There was no statistically significant difference in CFT between focal vs broad and concurrent vs isolated type VMT. Central (p = 0.009), nasal (p = 0.004), and temporal (p = 0.007) subfoveal choroidal thickness was significantly higher in broad VMT compared to focal VMT. There was difference in both CFT (p = 0.035) and central (p = 0.005), nasal (p = 0.01), and temporal (p = 0.001) choroidal thickness between moderate and severe VMT. There was a correlation between VMFA and CFT, where a wider angle was associated with increased CFT (p = 0.026). The broader VMA was associated with increased central subfoveal (p = 0.032), nasal (p = 0.05), and temporal (p = 0.01) choroidal thickness. CONCLUSIONS: Eyes with broad VMT have thicker choroid than eyes with focal VMT, which have a more open vitreomacular angle. The angle of VMT is related to distinct CFTs. FAU - Kozak, Igor AU - Kozak I AD - a King Khaled Eye Specialist Hospital , Riyadh , Saudi Arabia. FAU - Barteselli, Giulio AU - Barteselli G AD - b Ophthalmological Unit, Department of Clinical Sciences and Community Health , Ca' Granda Foundation-Ospedale Maggiore Policlinico, University of Milan , Milan , Italy. AD - c Genentech Inc ., South San Francisco , CA , USA. FAU - Sepah, Yasir J AU - Sepah YJ AD - d Truhlsen Eye Institute, University of Nebraska Medical Center , Omaha , NE , USA. FAU - Sadiq, Mohammad Ali AU - Sadiq MA AD - d Truhlsen Eye Institute, University of Nebraska Medical Center , Omaha , NE , USA. FAU - High, Robin AU - High R AD - e Maurer College of Public Health at the University of Nebraska Medical Center Omaha , NE , USA. FAU - Do, Diana V AU - Do DV AD - d Truhlsen Eye Institute, University of Nebraska Medical Center , Omaha , NE , USA. FAU - Nguyen, Quan Dong AU - Nguyen QD AD - d Truhlsen Eye Institute, University of Nebraska Medical Center , Omaha , NE , USA. LA - eng PT - Journal Article PT - Multicenter Study DEP - 20160630 PL - England TA - Curr Eye Res JT - Current eye research JID - 8104312 SB - IM MH - Female MH - Fovea Centralis/*pathology MH - Humans MH - Macula Lutea/pathology MH - Male MH - Middle Aged MH - Retrospective Studies MH - Tomography, Optical Coherence/*methods MH - *Visual Acuity MH - Vitreous Body/*pathology/surgery MH - Vitreous Detachment/pathology/*surgery OTO - NOTNLM OT - Choroidal thickness OT - enhanced depth imaging OT - spectral domain optical coherence tomograph OT - vitreomacular traction EDAT- 2016/07/01 06:00 MHDA- 2017/12/05 06:00 CRDT- 2016/07/01 06:00 PHST- 2016/07/01 06:00 [pubmed] PHST- 2017/12/05 06:00 [medline] PHST- 2016/07/01 06:00 [entrez] AID - 10.1080/02713683.2016.1175020 [doi] PST - ppublish SO - Curr Eye Res. 2017 Feb;42(2):297-301. doi: 10.1080/02713683.2016.1175020. Epub 2016 Jun 30.