PMID- 27362667
OWN - NLM
STAT- MEDLINE
DCOM- 20180309
LR  - 20181202
IS  - 1556-4029 (Electronic)
IS  - 0022-1198 (Linking)
VI  - 61
IP  - 5
DP  - 2016 Sep
TI  - Development of a Library Search-Based Screening System for 
      3,4-Methylenedioxymethamphetamine in Ecstasy Tablets Using a Portable 
      Near-Infrared Spectrometer.
PG  - 1208-14
LID - 10.1111/1556-4029.13122 [doi]
AB  - This is the first report on development of a library search-based screening 
      system for 3,4-methylenedioxymethamphetamine (MDMA) in ecstasy tablets using a 
      portable near-infrared (NIR) spectrometer. The spectrum library consisted of 
      spectra originating from standard substances as well as mixtures of MDMA 
      hydrochloride (MDMA-HCl) and diluents. The raw NIR spectra were mathematically 
      pretreated, and then, a library search was performed using correlation 
      coefficient. To enhance the discrimination ability, the wavelength used for the 
      library search was limited. Mixtures of MDMA-HCl and diluents were used to decide 
      criteria to judge MDMA-positive or MDMA-negative. Confiscated MDMA tablets and 
      medicinal tablets were used for performance check of the criteria. Twenty-two of 
      27 MDMA tablets were truly judged as MDMA-positive. Five false-negative results 
      may be caused by compounds not included in the library. No false-positive results 
      were obtained for medicinal tablets. This system will be a useful tool for 
      on-site screening of MDMA tablets.
CI  - (c) 2016 American Academy of Forensic Sciences.
FAU - Tsujikawa, Kenji
AU  - Tsujikawa K
AD  - National Research Institute of Police Science, 6-3-1 Kashiwanoha, Kashiwa, Chiba, 
      277-0882, Japan. tujikawa@nrips.go.jp.
FAU - Yamamuro, Tadashi
AU  - Yamamuro T
AD  - National Research Institute of Police Science, 6-3-1 Kashiwanoha, Kashiwa, Chiba, 
      277-0882, Japan.
FAU - Kuwayama, Kenji
AU  - Kuwayama K
AD  - National Research Institute of Police Science, 6-3-1 Kashiwanoha, Kashiwa, Chiba, 
      277-0882, Japan.
FAU - Kanamori, Tatsuyuki
AU  - Kanamori T
AD  - National Research Institute of Police Science, 6-3-1 Kashiwanoha, Kashiwa, Chiba, 
      277-0882, Japan.
FAU - Iwata, Yuko T
AU  - Iwata YT
AD  - National Research Institute of Police Science, 6-3-1 Kashiwanoha, Kashiwa, Chiba, 
      277-0882, Japan.
FAU - Miyamoto, Kazuna
AU  - Miyamoto K
AD  - Biochemical Toxicology Laboratory, Faculty of Pharmaceutical Sciences, Kobegakuin 
      University, 1-1-3 Minatojima, Chuo-ku, Kobe, Hyogo, 650-8586, Japan.
FAU - Kasuya, Fumiyo
AU  - Kasuya F
AD  - Biochemical Toxicology Laboratory, Faculty of Pharmaceutical Sciences, Kobegakuin 
      University, 1-1-3 Minatojima, Chuo-ku, Kobe, Hyogo, 650-8586, Japan.
FAU - Inoue, Hiroyuki
AU  - Inoue H
AD  - National Research Institute of Police Science, 6-3-1 Kashiwanoha, Kashiwa, Chiba, 
      277-0882, Japan.
LA  - eng
PT  - Journal Article
DEP - 20160630
PL  - United States
TA  - J Forensic Sci
JT  - Journal of forensic sciences
JID - 0375370
RN  - 0 (Hallucinogens)
RN  - 0 (Tablets)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
SB  - IM
MH  - Hallucinogens/*analysis
MH  - N-Methyl-3,4-methylenedioxyamphetamine/*analysis
MH  - Spectrum Analysis/*methods
MH  - Tablets/chemistry
OTO - NOTNLM
OT  - 3,4-methylenedioxymethamphetamine
OT  - ecstasy
OT  - forensic science
OT  - library search
OT  - near-infrared spectrometry
OT  - on-site screening
EDAT- 2016/07/01 06:00
MHDA- 2018/03/10 06:00
CRDT- 2016/07/01 06:00
PHST- 2015/03/30 00:00 [received]
PHST- 2015/11/01 00:00 [revised]
PHST- 2015/11/14 00:00 [accepted]
PHST- 2016/07/01 06:00 [entrez]
PHST- 2016/07/01 06:00 [pubmed]
PHST- 2018/03/10 06:00 [medline]
AID - 10.1111/1556-4029.13122 [doi]
PST - ppublish
SO  - J Forensic Sci. 2016 Sep;61(5):1208-14. doi: 10.1111/1556-4029.13122. Epub 2016 
      Jun 30.