PMID- 27363407
OWN - NLM
STAT- MEDLINE
DCOM- 20170411
LR  - 20181202
IS  - 1434-4726 (Electronic)
IS  - 0937-4477 (Linking)
VI  - 273
IP  - 12
DP  - 2016 Dec
TI  - Effects of triamcinolone-impregnated nasal dressing on subjective and objective 
      outcomes following endoscopic sinus surgery.
PG  - 4351-4357
LID - 10.1007/s00405-016-4185-0 [doi]
AB  - The aim of this study was to compare the effects of triamcinolone (TA)- and 
      saline-soaked biodegradable nasal dressing on subjective symptoms, wound healing 
      and improvement of olfactory dysfunction in patients with chronic rhinosinusitis 
      with nasal polyposis (CRSwNP) after undergoing endoscopic sinus surgery (ESS). 
      The study was a prospective, randomized, double-blinded, placebo-controlled 
      study. A total of 80 patients undergoing bilateral ESS for CRSwNP were enrolled 
      and randomly assigned to two groups. Nasal dressing was impregnated with normal 
      saline in the control group, while patients received triamcinolone-impregnated 
      dressing in the TA group. Sino-Nasal Outcome Test 20 (SNOT-20) and Korean Version 
      of the Sniffin' Stick (KVSS) II test were used to assess the patients' condition 
      preoperatively and at postoperative 1 and 3 months. Lund-Kennedy (L-K) and 
      perioperative sinus endoscopy (POSE) scores were assessed on postoperative months 
      1, 2, and 3. There were significant differences between the control group and the 
      TA group in terms of postoperative L-K scores and POSE scores at 1 and 2 months. 
      The postoperative endoscopic scores were significantly decreased in the TA group 
      compared to the control at 1 month. Olfactory functions were significantly 
      improved at postoperative 3 months (p = 0.0099) compared to the preoperative 
      score in the TA group. Significant improvement in the olfactory functions among 
      anosmic and hyposmic patients at postoperative 1 month (p = 0.0475) and 3 months 
      (p = 0.0019) compared to their preoperative olfactory function score was observed 
      only in the TA group. TA-impregnated dressing had a significant advantage over 
      saline-soaked dressing with regard to postoperative wound healing and improvement 
      of olfactory function.
FAU - Xu, Jun
AU  - Xu J
AD  - Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National 
      University School of Medicine, 282 Munhwa-ro, Jung-gu, Daejeon, 35015, Korea.
AD  - Yanbian University Hospital, Yanji, Jilin, China.
FAU - Park, Sung Je
AU  - Park SJ
AD  - Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National 
      University School of Medicine, 282 Munhwa-ro, Jung-gu, Daejeon, 35015, Korea.
FAU - Park, Hee Sung
AU  - Park HS
AD  - Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National 
      University School of Medicine, 282 Munhwa-ro, Jung-gu, Daejeon, 35015, Korea.
FAU - Han, Ruining
AU  - Han R
AD  - Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National 
      University School of Medicine, 282 Munhwa-ro, Jung-gu, Daejeon, 35015, Korea.
AD  - Yanbian University Hospital, Yanji, Jilin, China.
FAU - Rha, Ki-Sang
AU  - Rha KS
AD  - Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National 
      University School of Medicine, 282 Munhwa-ro, Jung-gu, Daejeon, 35015, Korea.
FAU - Kim, Yong Min
AU  - Kim YM
AD  - Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National 
      University School of Medicine, 282 Munhwa-ro, Jung-gu, Daejeon, 35015, Korea. 
      entkym@cnu.ac.kr.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20160630
PL  - Germany
TA  - Eur Arch Otorhinolaryngol
JT  - European archives of oto-rhino-laryngology : official journal of the European 
      Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the 
      German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
JID - 9002937
RN  - 0 (Anti-Inflammatory Agents)
RN  - 1ZK20VI6TY (Triamcinolone)
SB  - IM
MH  - Absorbable Implants
MH  - Adult
MH  - Aged
MH  - Anti-Inflammatory Agents/administration & dosage/*pharmacology
MH  - *Bandages
MH  - Chronic Disease
MH  - Double-Blind Method
MH  - Endoscopy
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Nasal Polyps/*surgery
MH  - Paranasal Sinuses/surgery
MH  - Prospective Studies
MH  - Quality of Life
MH  - Rhinitis/*surgery
MH  - Sinusitis/*surgery
MH  - Smell
MH  - Treatment Outcome
MH  - Triamcinolone/administration & dosage/*pharmacology
MH  - Wound Healing
OTO - NOTNLM
OT  - Nasal dressings
OT  - Nasal polyps
OT  - Olfactory
OT  - Triamcinolone
EDAT- 2016/07/02 06:00
MHDA- 2017/04/12 06:00
CRDT- 2016/07/02 06:00
PHST- 2016/01/22 00:00 [received]
PHST- 2016/06/27 00:00 [accepted]
PHST- 2016/07/02 06:00 [pubmed]
PHST- 2017/04/12 06:00 [medline]
PHST- 2016/07/02 06:00 [entrez]
AID - 10.1007/s00405-016-4185-0 [pii]
AID - 10.1007/s00405-016-4185-0 [doi]
PST - ppublish
SO  - Eur Arch Otorhinolaryngol. 2016 Dec;273(12):4351-4357. doi: 
      10.1007/s00405-016-4185-0. Epub 2016 Jun 30.