PMID- 27364896
OWN - NLM
STAT- MEDLINE
DCOM- 20170403
LR  - 20201209
IS  - 1573-0832 (Electronic)
IS  - 0301-486X (Linking)
VI  - 181
IP  - 11-12
DP  - 2016 Dec
TI  - Severe Paracoccidioidomycosis in a 14-Year-Old Boy.
PG  - 915-920
AB  - Paracoccidioidomycosis (PCM) is the most important systemic mycoses in Latin 
      America. We describe a severe case of paracoccidioidomycosis in a 14-year-old 
      boy, with a rapid disease progression. The fungal strain was isolated and 
      inoculated into a T and/or B cell immunocompromised mice, which revealed a highly 
      virulent strain. The case report presented herein emphasizes the importance of 
      considering PCM in the differential diagnosis of patients with other infectious 
      diseases in endemic areas and highlights a novel isolate.
FAU - Ruas, L P
AU  - Ruas LP
AD  - Department of Clinical Pathology, School of Medical Sciences, State University of 
      Campinas (UNICAMP), Rua Tessalia Vieira de Camargo, 126, Campinas, Sao Paulo, 
      13083-878, Brazil.
FAU - Pereira, R M
AU  - Pereira RM
AD  - Department of Pediatrics, School of Medical Sciences, State University of 
      Campinas (UNICAMP), Campinas, Sao Paulo, Brazil.
FAU - Braga, F G
AU  - Braga FG
AD  - Department of Clinical Pathology, School of Medical Sciences, State University of 
      Campinas (UNICAMP), Rua Tessalia Vieira de Camargo, 126, Campinas, Sao Paulo, 
      13083-878, Brazil.
FAU - Lima, X T
AU  - Lima XT
AD  - Department of Clinical Pathology, School of Medical Sciences, State University of 
      Campinas (UNICAMP), Rua Tessalia Vieira de Camargo, 126, Campinas, Sao Paulo, 
      13083-878, Brazil.
AD  - School of Medicine, University of Fortaleza (UNIFOR), Fortaleza, Ceara, Brazil.
FAU - Mamoni, R L
AU  - Mamoni RL
AD  - Department of Clinical Pathology, School of Medical Sciences, State University of 
      Campinas (UNICAMP), Rua Tessalia Vieira de Camargo, 126, Campinas, Sao Paulo, 
      13083-878, Brazil.
FAU - Cintra, M L
AU  - Cintra ML
AD  - Department of Pathology, School of Medical Sciences, State University of Campinas 
      (UNICAMP), Campinas, Sao Paulo, Brazil.
FAU - Schreiber, A Z
AU  - Schreiber AZ
AD  - Department of Clinical Pathology, School of Medical Sciences, State University of 
      Campinas (UNICAMP), Rua Tessalia Vieira de Camargo, 126, Campinas, Sao Paulo, 
      13083-878, Brazil.
FAU - Calich, V L G
AU  - Calich VL
AD  - Department of Immunology, Institute of Biomedical Sciences, University of Sao 
      Paulo, Sao Paulo, Brazil.
FAU - Blotta, M H S L
AU  - Blotta MH
AD  - Department of Clinical Pathology, School of Medical Sciences, State University of 
      Campinas (UNICAMP), Rua Tessalia Vieira de Camargo, 126, Campinas, Sao Paulo, 
      13083-878, Brazil. heblotta@fcm.unicamp.br.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20160630
PL  - Netherlands
TA  - Mycopathologia
JT  - Mycopathologia
JID - 7505689
SB  - IM
MH  - Adolescent
MH  - Animal Experimentation
MH  - Animals
MH  - Brazil
MH  - Histocytochemistry
MH  - Humans
MH  - Immunocompromised Host
MH  - Lymph Nodes/pathology
MH  - Male
MH  - Mice
MH  - Microscopy
MH  - Paracoccidioides/*isolation & purification/pathogenicity
MH  - Paracoccidioidomycosis/*diagnosis/microbiology/*pathology
MH  - Survival Analysis
OTO - NOTNLM
OT  - Case report
OT  - Fungal infection
OT  - Paracoccidioidomycosis
OT  - Virulent strain
EDAT- 2016/07/02 06:00
MHDA- 2017/04/04 06:00
CRDT- 2016/07/02 06:00
PHST- 2016/04/11 00:00 [received]
PHST- 2016/06/23 00:00 [accepted]
PHST- 2016/07/02 06:00 [pubmed]
PHST- 2017/04/04 06:00 [medline]
PHST- 2016/07/02 06:00 [entrez]
AID - 10.1007/s11046-016-0035-2 [pii]
AID - 10.1007/s11046-016-0035-2 [doi]
PST - ppublish
SO  - Mycopathologia. 2016 Dec;181(11-12):915-920. doi: 10.1007/s11046-016-0035-2. Epub 
      2016 Jun 30.