PMID- 27365108
OWN - NLM
STAT- MEDLINE
DCOM- 20161221
LR  - 20181202
IS  - 1435-604X (Electronic)
IS  - 0268-8921 (Linking)
VI  - 31
IP  - 8
DP  - 2016 Nov
TI  - A comparison of incidences of bladder neck contracture of 80- versus 180-W 
      GreenLight laser photoselective vaporization of benign prostatic hyperplasia.
PG  - 1573-1581
AB  - Bladder neck contracture (BNC) after GreenLight laser photoselective vaporization 
      (PVP) of benign prostatic hyperplasia is a common complication. In the present 
      study, data of patients received 80 or 180 W PVP were collected. Perioperative 
      parameters, including applied energy, irradiation time, catheter removal time, 
      and hospital stay, were recorded. Postoperative parameters, including maximum 
      urinary flow rate, International Prostate Symptom Score, post-void residual 
      volume, and incidences of BNC, were recorded at 3 and 12 months after operations. 
      Bladder neck tissues were taken at 3 months after operations for 
      immunohistochemical staining and western blot analysis to examine the expressions 
      of collagen I, matrix metalloproteinase-3 (MMP-3), and transforming growth 
      factor-beta (TGF-beta). Sample size of patients was calculated with a power of 80 %. 
      Chi-square test and one-way analysis of variance were performed as statistical 
      methods. Three hundred twenty-six patients who received potassium titanyl 
      phosphate (KTP) laser and 256 who received X-ray photoelectron spectroscopy (XPS) 
      laser entered into the study. Perioperative parameters were comparable, except 
      for shorter irradiation time in 180 W group (P = 0.032). Postoperative parameters 
      were also similar, except for higher incidence of BNC in 80 W group at 3 months 
      after operations (P = 0.022). Immunohistochemical staining and western blot 
      analysis showed higher expressions of collagen I, MMP-3, and TGF-beta in 80 W group 
      than in 180 W group. In conclusion, 80 W GreenLight laser showed a comparable 
      efficacy with 180-W laser in PVP but showed a higher incidence of BNC in short 
      term, which might be the result of up-regulated fibrotic factors in bladder neck 
      triggered by lasers.
FAU - Hu, Bo
AU  - Hu B
AD  - Minimally Invasive Urology Center, Shandong Provincial Hospital affiliated to 
      Shandong University, 324 Jing5 Wei7 Road, Jinan, 250021, China.
FAU - Song, Zhenyu
AU  - Song Z
AD  - Minimally Invasive Urology Center, Shandong Provincial Hospital affiliated to 
      Shandong University, 324 Jing5 Wei7 Road, Jinan, 250021, China.
FAU - Liu, Hui
AU  - Liu H
AD  - Cystoscope Center, Shandong Provincial Hospital affiliated to Shandong 
      University, Jinan, 250021, China.
FAU - Qiao, Liang
AU  - Qiao L
AD  - Department of Urology, Weifang People's Hospital, Weifang Medical College, 
      Weifang, 261599, China.
FAU - Zhao, Yong
AU  - Zhao Y
AD  - Minimally Invasive Urology Center, Shandong Provincial Hospital affiliated to 
      Shandong University, 324 Jing5 Wei7 Road, Jinan, 250021, China.
FAU - Wang, Muwen
AU  - Wang M
AD  - Minimally Invasive Urology Center, Shandong Provincial Hospital affiliated to 
      Shandong University, 324 Jing5 Wei7 Road, Jinan, 250021, China.
FAU - Song, Wei
AU  - Song W
AD  - Minimally Invasive Urology Center, Shandong Provincial Hospital affiliated to 
      Shandong University, 324 Jing5 Wei7 Road, Jinan, 250021, China.
FAU - Zhang, Dong
AU  - Zhang D
AD  - Minimally Invasive Urology Center, Shandong Provincial Hospital affiliated to 
      Shandong University, 324 Jing5 Wei7 Road, Jinan, 250021, China.
FAU - Jin, Xunbo
AU  - Jin X
AD  - Minimally Invasive Urology Center, Shandong Provincial Hospital affiliated to 
      Shandong University, 324 Jing5 Wei7 Road, Jinan, 250021, China.
FAU - Zhang, Haiyang
AU  - Zhang H
AD  - Minimally Invasive Urology Center, Shandong Provincial Hospital affiliated to 
      Shandong University, 324 Jing5 Wei7 Road, Jinan, 250021, China. 
      zhy.sdu@hotmail.com.
AD  - Knuppe Molecular Urology Laboratory, Department of Urology, School of Medicine, 
      University of California, San Francisco, CA, 94143, USA. zhy.sdu@hotmail.com.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20160630
PL  - England
TA  - Lasers Med Sci
JT  - Lasers in medical science
JID - 8611515
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Contracture/*epidemiology/pathology
MH  - Humans
MH  - Incidence
MH  - Laser Therapy/*adverse effects
MH  - Lasers, Solid-State/*therapeutic use
MH  - Male
MH  - Middle Aged
MH  - Photoelectron Spectroscopy
MH  - Postoperative Complications/*epidemiology/pathology
MH  - Prostatic Hyperplasia/*surgery
MH  - Retrospective Studies
MH  - Treatment Outcome
MH  - Urinary Bladder/*pathology
OTO - NOTNLM
OT  - Benign prostatic hyperplasia
OT  - Bladder neck contracture
OT  - GreenLight laser
OT  - Photoselective vaporization of prostate
OT  - Transurethral resection of prostate
EDAT- 2016/07/02 06:00
MHDA- 2016/12/22 06:00
CRDT- 2016/07/02 06:00
PHST- 2016/03/18 00:00 [received]
PHST- 2016/06/24 00:00 [accepted]
PHST- 2016/07/02 06:00 [pubmed]
PHST- 2016/12/22 06:00 [medline]
PHST- 2016/07/02 06:00 [entrez]
AID - 10.1007/s10103-016-2017-5 [pii]
AID - 10.1007/s10103-016-2017-5 [doi]
PST - ppublish
SO  - Lasers Med Sci. 2016 Nov;31(8):1573-1581. doi: 10.1007/s10103-016-2017-5. Epub 
      2016 Jun 30.