PMID- 27367416 OWN - NLM STAT- MEDLINE DCOM- 20171211 LR - 20171211 IS - 1744-5205 (Electronic) IS - 0882-0538 (Linking) VI - 32 IP - 6 DP - 2017 TI - Optic Nerve Parameters in Obese Children as Measured by Spectral Domain Optical Coherence Tomography. PG - 743-747 LID - 10.1080/08820538.2016.1177095 [doi] AB - PURPOSE: To investigate whether an association exists between obesity and optic nerve parameters. METHODS: This was a prospective comparative study including 125 eyes of 63 obese and 122 eyes of 62 healthy pediatric subjects. Optic nerve measurements were performed using the Cirrus spectral domain optical coherence tomograph (SD-OCT). RESULTS: The disc area, cup volume, mean and vertical C/D ratio, inferior and temporal RNFL thickness values were significantly higher in the control group than the obese group; however, age, sex, mean, superior and nasal RNFL thickness and rim area measurements were not statistically significantly different between the two groups. Age was significantly negatively correlated with temporal RNFL thickness in the obese group. Girls had significantly higher rim area, mean and superior RNFL thickness, and lower cup volume and vertical C/D ratio than boys in the obese group. CONCLUSION: These results could be helpful in the diagnosis and follow-up of obese children. FAU - Koca, Semra AU - Koca S AD - a Ankara Numune Training and Research Hospital , Ankara , Turkey. FAU - Keskin, Meliksah AU - Keskin M AD - b Dr. Sami Ulus Training and Research Hospital of Women's and Children's Health and Diseases , Ankara , Turkey. FAU - Saricaoglu, M Sinan AU - Saricaoglu MS AD - a Ankara Numune Training and Research Hospital , Ankara , Turkey. FAU - Koca, Serkan Bilge AU - Koca SB AD - c School of Medicine , Hacettepe University , Ankara , Turkey. FAU - Duru, Necati AU - Duru N AD - d Kayseri Education and Research Hospital , Kayseri , Turkey. FAU - Sahin Hamurcu, Mualla AU - Sahin Hamurcu M AD - a Ankara Numune Training and Research Hospital , Ankara , Turkey. FAU - Sahin Muratoglu, Nursel AU - Sahin Muratoglu N AD - b Dr. Sami Ulus Training and Research Hospital of Women's and Children's Health and Diseases , Ankara , Turkey. FAU - Aycan, Zehra AU - Aycan Z AD - b Dr. Sami Ulus Training and Research Hospital of Women's and Children's Health and Diseases , Ankara , Turkey. LA - eng PT - Comparative Study PT - Journal Article DEP - 20160701 PL - England TA - Semin Ophthalmol JT - Seminars in ophthalmology JID - 8610759 SB - IM MH - Adolescent MH - Case-Control Studies MH - Child MH - Female MH - Humans MH - Male MH - Nerve Fibers/pathology MH - Obesity/*pathology MH - Optic Disk/pathology MH - Optic Nerve/*pathology MH - Prospective Studies MH - Retinal Ganglion Cells/pathology MH - Sex Factors MH - Tomography, Optical Coherence/methods OTO - NOTNLM OT - Obesity OT - optical coherence tomography OT - pediatric OT - retinal nerve fiber OT - spectral domain EDAT- 2016/07/02 06:00 MHDA- 2017/12/12 06:00 CRDT- 2016/07/02 06:00 PHST- 2016/07/02 06:00 [pubmed] PHST- 2017/12/12 06:00 [medline] PHST- 2016/07/02 06:00 [entrez] AID - 10.1080/08820538.2016.1177095 [doi] PST - ppublish SO - Semin Ophthalmol. 2017;32(6):743-747. doi: 10.1080/08820538.2016.1177095. Epub 2016 Jul 1.