PMID- 27371364
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20191120
IS  - 0040-5957 (Print)
IS  - 0040-5957 (Linking)
VI  - 71
IP  - 6
DP  - 2016 Dec
TI  - [The current aspects of the use of ecstasy/MDMA in France].
PG  - 553-562
LID - S0040-5957(16)30057-9 [pii]
LID - 10.1016/j.therap.2016.05.005 [doi]
AB  - Methylenedioxymethamphetamine (MDMA), the active compound of ecstasy, has been 
      used for several years, especially by young adults to benefit of psychostimulant 
      properties. By raising the level of neuromodulators in the synapsis, MDMA can 
      cause psychiatric and physical injuries. After reduced supplies in 2009 (number 
      of ecstasy seizures equal to 10 percent of those recorded in 2002), judicial 
      authorities now observed an increased availability (a half more part of seizures 
      in 2012 than 2010). From its "Spontaneous Notifications" data base and "deaths in 
      connection with the abuse of medicine and substances (DRAMES)", "observation of 
      illegal drugs and misuse of psychotropic medications" (OPPIDUM), and "observation 
      of drug dependencies in ambulatory medicine" (OPEMA) national inquiries, the 
      French Addictovigilance network (CEIP-A) highlighted the increasing consumption 
      of MDMA. The way of use appeared quite unchanged: users were mainly young men 
      between 25 and 30 years; they favored an occasional use but mainly combined other 
      products such as alcohol, cannabis and other stimulants. Severity of the clinical 
      cases, based on hospital care and forensic data, could be consistent with the 
      higher amounts of MDMA measured in pills.
CI  - Copyright (c) 2016 Societe francaise de pharmacologie et de therapeutique. 
      Published by Elsevier Masson SAS. All rights reserved.
FAU - Spadari, Michel
AU  - Spadari M
AD  - Service de pharmacologie clinique et pharmacovigilance, centre d'addictovigilance 
      PACA-Corse, CHU, 13005 Marseille, France.
FAU - Batisse, Anne
AU  - Batisse A
AD  - Centre d'addictovigilance de Paris, hopital Fernand-Vidal, 75010 Paris, France.
FAU - Guerlais, Marylene
AU  - Guerlais M
AD  - Centre d'addictovigilance de Nantes, institut de biologie, 44093 Nantes, France.
FAU - Boucher, Alexandra
AU  - Boucher A
AD  - Centre d'addictovigilance de Lyon, CHU, 69424 Lyon, France.
FAU - Daveluy, Amelie
AU  - Daveluy A
AD  - Centre d'addictovigilance de Bordeaux, CHU, 33076 Bordeaux, France.
FAU - Le Boisselier, Reynald
AU  - Le Boisselier R
AD  - Service de pharmacologie, centre d'addictovigilance de Caen, CHU Cote de Nacre, 
      14033 Caen cedex 09, France.
FAU - Gibaja, Valerie
AU  - Gibaja V
AD  - Centre d'addictovigilance de Nancy, hopital Central, 54035 Nancy, France.
FAU - Eiden, Celine
AU  - Eiden C
AD  - Centre d'addictovigilance de Montpellier, hopital Lapeyronie, 34295 Montpellier, 
      France.
FAU - Lepelley, Marion
AU  - Lepelley M
AD  - Centre d'addictovigilance de Grenoble, CHU, 38043 Grenoble, France.
FAU - Roussin, Anne
AU  - Roussin A
AD  - Centre d'addictovigilance de Toulouse, faculte de medecine, 31000 Toulouse, 
      France.
FAU - Deheul, Sylvie
AU  - Deheul S
AD  - Centre d'addictovigilance de Lille, faculte de medecine, 59045 Lille, France.
FAU - Frauger, Elisabeth
AU  - Frauger E
AD  - Service de pharmacologie clinique et pharmacovigilance, centre d'addictovigilance 
      PACA-Corse, CHU, 13005 Marseille, France.
FAU - Debruyne, Daniele
AU  - Debruyne D
AD  - Service de pharmacologie, centre d'addictovigilance de Caen, CHU Cote de Nacre, 
      14033 Caen cedex 09, France. Electronic address: debruyne-d@chu-caen.fr.
LA  - fre
PT  - English Abstract
PT  - Journal Article
TT  - Les aspects actuels de l'usage de l'ecstasy/MDMA en France.
DEP - 20160607
PL  - France
TA  - Therapie
JT  - Therapie
JID - 0420544
OTO - NOTNLM
OT  - Addictovigilance
OT  - Ecstasy
OT  - MDMA
EDAT- 2016/07/03 06:00
MHDA- 2016/07/03 06:01
CRDT- 2016/07/03 06:00
PHST- 2016/02/26 00:00 [received]
PHST- 2016/05/02 00:00 [accepted]
PHST- 2016/07/03 06:00 [pubmed]
PHST- 2016/07/03 06:01 [medline]
PHST- 2016/07/03 06:00 [entrez]
AID - S0040-5957(16)30057-9 [pii]
AID - 10.1016/j.therap.2016.05.005 [doi]
PST - ppublish
SO  - Therapie. 2016 Dec;71(6):553-562. doi: 10.1016/j.therap.2016.05.005. Epub 2016 
      Jun 7.