PMID- 27371497
OWN - NLM
STAT- MEDLINE
DCOM- 20171227
LR  - 20191210
IS  - 1461-7285 (Electronic)
IS  - 0269-8811 (Linking)
VI  - 30
IP  - 12
DP  - 2016 Dec
TI  - Mephedrone and 3,4-methylenedioxy-methamphetamine: Comparative psychobiological 
      effects as reported by recreational polydrug users.
PG  - 1313-1320
AB  - AIMS: The purpose of this study was to compare the effects of mephedrone and 
      3,4-methylenedioxy-methamphetamine (MDMA), as reported by young recreational 
      polydrug users. METHODS: 152 MDMA users and 81 mephedrone users were recruited 
      through snowballing on social network sites. They completed a standard online 
      questionnaire for either mephedrone or MDMA. The questions covered the average 
      amount taken per session, the longest duration of usage in the last 12-months, 
      subjective effects while on-drug, and recovery effects in the days afterwards. 
      RESULTS: Mephedrone users reported a significantly longer maximum session of use 
      than MDMA users. Mephedrone users also reported a significantly greater average 
      amount used per session. The majority of on-drug subjective ratings did not 
      differ between drugs, with similar increases in entactogenic effects. Although 
      mephedrone users did report significantly more frequent issues with sleeping, 
      anger and anxiety. In relation to recovery, mephedrone users reported more 
      frequent craving, nasal irritation, paranoia, and relationship difficulties. 
      Mephedrone users also rated general recovery effects as more severe over the 
      seven-day period following use, taking more days to feel normal. CONCLUSIONS: The 
      acute effects of MDMA and mephedrone were broadly similar. However, the recovery 
      period for mephedrone was more enduring, possibly due to the longer duration of 
      acute session usage.
CI  - (c) The Author(s) 2016.
FAU - Jones, Lewis
AU  - Jones L
AD  - Psychology Department, Swansea University, Swansea, UK 
      lewisjones010791@gmail.com.
FAU - Reed, Phil
AU  - Reed P
AD  - Psychology Department, Swansea University, Swansea, UK.
FAU - Parrott, Andrew
AU  - Parrott A
AD  - Psychology Department, Swansea University, Swansea, UK.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20160701
PL  - United States
TA  - J Psychopharmacol
JT  - Journal of psychopharmacology (Oxford, England)
JID - 8907828
RN  - 0 (Illicit Drugs)
RN  - 44RAL3456C (Methamphetamine)
RN  - 8BA8T27317 (mephedrone)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
SB  - IM
MH  - Adult
MH  - Anger/drug effects
MH  - Anxiety/chemically induced
MH  - Cross-Sectional Studies
MH  - Female
MH  - Humans
MH  - Illicit Drugs/adverse effects
MH  - Male
MH  - Methamphetamine/administration & dosage/adverse effects/*analogs & derivatives
MH  - N-Methyl-3,4-methylenedioxyamphetamine/*administration & dosage/*adverse effects
MH  - Sleep/drug effects
MH  - Surveys and Questionnaires
OTO - NOTNLM
OT  - 3,4-methylenedioxy-methamphetamine
OT  - Mephedrone
OT  - cathinone
OT  - entactogen
OT  - stimulant
EDAT- 2016/07/03 06:00
MHDA- 2017/12/28 06:00
CRDT- 2016/07/03 06:00
PHST- 2016/07/03 06:00 [pubmed]
PHST- 2017/12/28 06:00 [medline]
PHST- 2016/07/03 06:00 [entrez]
AID - 0269881116653106 [pii]
AID - 10.1177/0269881116653106 [doi]
PST - ppublish
SO  - J Psychopharmacol. 2016 Dec;30(12):1313-1320. doi: 10.1177/0269881116653106. Epub 
      2016 Jul 1.