PMID- 27375928
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20160704
LR  - 20200930
IS  - 2156-7085 (Print)
IS  - 2156-7085 (Electronic)
IS  - 2156-7085 (Linking)
VI  - 7
IP  - 6
DP  - 2016 Jun 1
TI  - Nanoparticle-free tissue-mimicking phantoms with intrinsic scattering.
PG  - 2088-94
LID - 10.1364/BOE.7.002088 [doi]
AB  - We present an alternative to the conventional approach, phantoms without 
      scattering nanoparticles, where scattering is achieved by the material itself: 
      spherical cavities trapped in a silicone matrix. We describe the properties and 
      fabrication of novel optical phantoms based on a silicone elastomer 
      polydimethylsiloxane (PDMS) and glycerol mixture. Optical properties (absorption 
      coefficient microa , reduced scattering coefficient micros' , and anisotropy factor g) of 
      the fabricated phantoms were retrieved from spectrophotometric measurements (in 
      the 400-1100 nm wavelength range) using the inverse adding-doubling method. The 
      internal structure of the phantoms was studied under a scanning electron 
      microscope, and the chemical composition was assessed by Raman spectroscopy. 
      Composition of the phantom material is reported along with the full 
      characterization of the produced phantoms and ways to control their parameters.
FAU - Wrobel, Maciej S
AU  - Wrobel MS
AD  - Gdansk University of Technology, Faculty of Electronics, Telecommunications and 
      Informatics, Department of Metrology and Optoelectronics, Gabriela Narutowicza 
      Str. 11/12, 80-233 Gdansk, Poland.
FAU - Popov, Alexey P
AU  - Popov AP
AD  - University of Oulu, Faculty of Information Technology and Electrical Engineering, 
      Optoelectronics and Measurement Techniques Laboratory, P.O. Box 4500, FI-90014 
      Oulu, Finland.
FAU - Bykov, Alexander V
AU  - Bykov AV
AD  - University of Oulu, Faculty of Information Technology and Electrical Engineering, 
      Optoelectronics and Measurement Techniques Laboratory, P.O. Box 4500, FI-90014 
      Oulu, Finland.
FAU - Tuchin, Valery V
AU  - Tuchin VV
AD  - University of Oulu, Faculty of Information Technology and Electrical Engineering, 
      Optoelectronics and Measurement Techniques Laboratory, P.O. Box 4500, FI-90014 
      Oulu, Finland; Saratov National Research State University, Research-Education 
      Institute of Optics and Biophotonics, 410012 Saratov, Russia; Institute of 
      Precision Mechanics and Control of Russian Academy of Sciences, 410028 Saratov, 
      Russia; National Research Tomsk State University, Laboratory of Biophotonics, 
      634050 Tomsk, Russia.
FAU - Jedrzejewska-Szczerska, Malgorzata
AU  - Jedrzejewska-Szczerska M
AD  - Gdansk University of Technology, Faculty of Electronics, Telecommunications and 
      Informatics, Department of Metrology and Optoelectronics, Gabriela Narutowicza 
      Str. 11/12, 80-233 Gdansk, Poland.
LA  - eng
PT  - Journal Article
DEP - 20160504
PL  - United States
TA  - Biomed Opt Express
JT  - Biomedical optics express
JID - 101540630
PMC - PMC4918566
OTO - NOTNLM
OT  - (160.0160) Materials
OT  - (160.4670) Optical materials
OT  - (160.4760) Optical properties
OT  - (170.0170) Medical optics and biotechnology
OT  - (170.3660) Light propagation in tissues
OT  - (170.7050) Turbid media
EDAT- 2016/07/05 06:00
MHDA- 2016/07/05 06:01
PMCR- 2016/05/04
CRDT- 2016/07/05 06:00
PHST- 2016/03/02 00:00 [received]
PHST- 2016/04/16 00:00 [revised]
PHST- 2016/04/28 00:00 [accepted]
PHST- 2016/07/05 06:00 [entrez]
PHST- 2016/07/05 06:00 [pubmed]
PHST- 2016/07/05 06:01 [medline]
PHST- 2016/05/04 00:00 [pmc-release]
AID - 260393 [pii]
AID - 10.1364/BOE.7.002088 [doi]
PST - epublish
SO  - Biomed Opt Express. 2016 May 4;7(6):2088-94. doi: 10.1364/BOE.7.002088. 
      eCollection 2016 Jun 1.