PMID- 27376154
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240325
IS  - 2471-8726 (Print)
IS  - 2471-8726 (Electronic)
IS  - 2471-8726 (Linking)
VI  - 2
IP  - 1
DP  - 2016 Mar
TI  - Understanding the Importance of Gene and Environment in the Etiology and 
      Prevention of Type 2 Diabetes Mellitus in High-Risk Populations.
LID - 112 [pii]
AB  - Current literature focuses on the complications and treatment of Type 2 Diabetes 
      Mellitus (T2DM) while clustering environmental and genetic factors to explain the 
      disease. Interventions proposed to reduce diabetes prevalence should focus 
      predominantly on initiating active rapports of family members and promoting a 
      more communication-oriented preventative approach between diabetics and 
      non-diabetics. Due to varying risks in T2DM by race and ethnicity, these 
      populations should follow race-appropriate guidelines to prevent further T2DM 
      occurrence and complications. The review consists of information related to the 
      genetic component of T2DM to help identify high-risk groups and focuses on the 
      environmental aspect of the disease to help consider appropriate techniques to 
      reduce disease burden. Genetic factors play important roles in the pathogenesis 
      of diabetes and thus are an essential element of understanding the cause of the 
      disease and possible methods of prevention. Focusing on high-risk groups with 
      T2DM could have profound effects on the current health care situation. In this 
      review, we discuss the epidemiology of diabetes in the United States and propose 
      methods of preventing and delaying the development of T2DM in high-risk 
      individuals.
FAU - Samsom, Marsha
AU  - Samsom M
AD  - Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
FAU - Trivedi, Tushar
AU  - Trivedi T
AD  - Cancer Prevention and Control Program, Arnold School of Public Health, University 
      of South Carolina, Columbia, South Carolina, USA.
FAU - Orekoya, Olubunmi
AU  - Orekoya O
AD  - Cancer Prevention and Control Program, Arnold School of Public Health, University 
      of South Carolina, Columbia, South Carolina, USA.
FAU - Vyas, Shraddha
AU  - Vyas S
AD  - Arnold School of Public Health, University of South Carolina, Columbia, SC, USA; 
      Cancer Prevention and Control Program, Arnold School of Public Health, University 
      of South Carolina, Columbia, South Carolina, USA.
LA  - eng
GR  - T32 GM081740/GM/NIGMS NIH HHS/United States
PT  - Journal Article
DEP - 20160314
PL  - United States
TA  - Oral Health Case Rep
JT  - Oral health case reports
JID - 101681924
PMC - PMC4926872
MID - NIHMS780144
OTO - NOTNLM
OT  - Diabetes mellitus
OT  - Genetics
OT  - High-Risk
OT  - Screening
EDAT- 2016/07/05 06:00
MHDA- 2016/07/05 06:01
PMCR- 2016/06/29
CRDT- 2016/07/05 06:00
PHST- 2016/07/05 06:00 [entrez]
PHST- 2016/07/05 06:00 [pubmed]
PHST- 2016/07/05 06:01 [medline]
PHST- 2016/06/29 00:00 [pmc-release]
AID - 112 [pii]
PST - ppublish
SO  - Oral Health Case Rep. 2016 Mar;2(1):112. Epub 2016 Mar 14.