PMID- 27377499
OWN - NLM
STAT- MEDLINE
DCOM- 20170529
LR  - 20181113
IS  - 0971-5916 (Print)
IS  - 0971-5916 (Linking)
VI  - 143
IP  - 4
DP  - 2016 Apr
TI  - Lifestyle related factors & impact of metabolic syndrome on quality of life, 
      level of functioning & self-esteem in patients with bipolar disorder & 
      schizophrenia.
PG  - 434-42
LID - 10.4103/0971-5916.184284 [doi]
AB  - BACKGROUND & OBJECTIVES: Though studies have reported high prevalence rates of 
      metabolic syndrome among patients with bipolar disorder (BPAD) and schizophrenia, 
      there is lack of data on the impact of the same on the patients' life. This study 
      was aimed to assess the lifestyle related factors associated with metabolic 
      syndrome (MetS) and to study the impact of MetS on functioning and quality of 
      life (QOL) in patients with BPAD and schizophrenia. METHODS: A total of 102 
      patients with BPAD and 72 patients with schizophrenia attending the output unit 
      of a tertiary care hospital in north India were evaluated for MetS. These 
      patients were assessed on Health Promoting Lifestyle Profile scale II (HPLP II), 
      World Health Organization QOL -Bref Version (WHOQOL-Bref), Impact of Weight on 
      Quality of Life- Lite version (IWOQOL -Lite), Body weight, Image and Self-esteem 
      Evaluation questionnaire (BWISE), Obesity-related Problem scale (OP scale) and 
      Global Assessment of Functioning (GAF) scale. RESULTS: MetS was associated with 
      lower scores on domains of health responsibility and nutrition habit domain on 
      HPLP-II scale in both groups, and additionally on physical activity and stress 
      management domain in BPAD group. On WHOQOL-Bref, MetS was associated with lower 
      scores on the domains of physical and psychological health in both groups. On 
      IWQOL-Lite, scores on personal distress and self esteem domains were higher in 
      those with obesity in both groups and also on physical activity domain in 
      schizophrenia group. Those with MetS had lower level of functioning as measured 
      by GAF in schizophrenia group. Fulfillment of higher number of criteria of MetS 
      correlated with poorer quality of life and higher problems in both groups. 
      INTERPRETATION & CONCLUSIONS: Many modifiable lifestyle factors increase the risk 
      of MetS. MetS was found to be associated with poorer QOL in patients with BPAD 
      and schizophrenia; in addition, obesity led to poor self-esteem and excessive 
      personal distress.
FAU - Malhotra, Nidhi
AU  - Malhotra N
AD  - Department of Psychiatry, Postgraduate Institute of Medical Education & Research, 
      Chandigarh, India.
FAU - Kulhara, Parmanand
AU  - Kulhara P
AD  - Department of Psychiatry, Postgraduate Institute of Medical Education & Research, 
      Chandigarh, India.
FAU - Chakrabarti, Subho
AU  - Chakrabarti S
AD  - Department of Psychiatry, Postgraduate Institute of Medical Education & Research, 
      Chandigarh, India.
FAU - Grover, Sandeep
AU  - Grover S
AD  - Department of Psychiatry, Postgraduate Institute of Medical Education & Research, 
      Chandigarh, India.
LA  - eng
PT  - Journal Article
PL  - India
TA  - Indian J Med Res
JT  - The Indian journal of medical research
JID - 0374701
SB  - IM
MH  - Adult
MH  - Bipolar Disorder/complications/*metabolism/physiopathology
MH  - Female
MH  - Humans
MH  - *Life Style
MH  - Male
MH  - Metabolic Syndrome/complications/metabolism/*physiopathology
MH  - Middle Aged
MH  - Quality of Life
MH  - Schizophrenia/complications/*metabolism/physiopathology
PMC - PMC4928549
COIS- Conflicts of Interest: None.
EDAT- 2016/07/06 06:00
MHDA- 2017/05/30 06:00
PMCR- 2016/04/01
CRDT- 2016/07/06 06:00
PHST- 2016/07/06 06:00 [entrez]
PHST- 2016/07/06 06:00 [pubmed]
PHST- 2017/05/30 06:00 [medline]
PHST- 2016/04/01 00:00 [pmc-release]
AID - IndianJMedRes_2016_143_4_434_184284 [pii]
AID - IJMR-143-434 [pii]
AID - 10.4103/0971-5916.184284 [doi]
PST - ppublish
SO  - Indian J Med Res. 2016 Apr;143(4):434-42. doi: 10.4103/0971-5916.184284.