PMID- 27382723
OWN - NLM
STAT- MEDLINE
DCOM- 20160712
LR  - 20190923
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 34
IP  - 2
DP  - 2016 Feb
TI  - [Determination of 23 antibiotics and 3 beta-agonists in livestock drinking water by 
      ultra performance liquid chromatography-tandem mass spectrometry coupled with 
      solid-phase extraction].
PG  - 176-83
AB  - A method has been developed for the simultaneous determination of 23 antibiotics 
      (four categories) and 3 beta-agonists in livestock drinking water using solid-phase 
      extraction and ultra performance liquid chromatography coupled with electrospray 
      ionization tandem mass spectrometry (UPLC-ESI MS/MS). The samples were adjusted 
      pH to 5. 0, added Na2EDTA, enriched and cleaned-up by an HLB solid-phase 
      extraction cartridge. The target compounds were confirmed and quantified by 
      UPLC-ESI MS/MS with external standard method for the anti- biotics and internal 
      standard method for the beta-agonists. The recoveries were assessed by using lab tap 
      water as matrix. The average recoveries of the 23 antibiotics and the 3 
      beta-agonists were in the range of 50. 7%-104. 6% and the relative standard 
      deviations (RSDs) were 2. 6%-8. 8% (n= 3). Under the optimal conditions, the 
      calibration curves of the 23 antibiotics and the 3 beta-agonists showed good 
      linearity with the correlation coefficients better than 0. 994. The limits of 
      detection (LODs, S/N>/=3) ranged from 0. 01-0. 20 ng/L. The developed method was 
      applied to analyze the livestock drinking waters in 36 Beijing intensive 
      livestock farms. The results showed that some antibiotics were detected.
FAU - Shi, Ao
AU  - Shi A
LA  - chi
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Adrenergic beta-Agonists)
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Drinking Water)
SB  - IM
MH  - Adrenergic beta-Agonists/*analysis
MH  - Animals
MH  - Anti-Bacterial Agents/*analysis
MH  - Beijing
MH  - *Chromatography, High Pressure Liquid
MH  - Drinking Water/*analysis
MH  - Limit of Detection
MH  - Livestock
MH  - Solid Phase Extraction
MH  - Spectrometry, Mass, Electrospray Ionization
MH  - *Tandem Mass Spectrometry
EDAT- 2016/07/08 06:00
MHDA- 2016/07/13 06:00
CRDT- 2016/07/08 06:00
PHST- 2016/07/08 06:00 [entrez]
PHST- 2016/07/08 06:00 [pubmed]
PHST- 2016/07/13 06:00 [medline]
AID - 10.3724/sp.j.1123.2015.09021 [doi]
PST - ppublish
SO  - Se Pu. 2016 Feb;34(2):176-83. doi: 10.3724/sp.j.1123.2015.09021.