PMID- 27382963
OWN - NLM
STAT- MEDLINE
DCOM- 20170724
LR  - 20191210
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 11
IP  - 7
DP  - 2016
TI  - Clinical Scores for Dyspnoea Severity in Children: A Prospective Validation 
      Study.
PG  - e0157724
LID - 10.1371/journal.pone.0157724 [doi]
LID - e0157724
AB  - BACKGROUND: In acute dyspnoeic children, assessment of dyspnoea severity and 
      treatment response is frequently based on clinical dyspnoea scores. Our study aim 
      was to validate five commonly used paediatric dyspnoea scores. METHODS: Fifty 
      children aged 0-8 years with acute dyspnoea were clinically assessed before and 
      after bronchodilator treatment, a subset of 27 children were videotaped and 
      assessed twice by nine observers. The observers scored clinical signs necessary 
      to calculate the Asthma Score (AS), Asthma Severity Score (ASS), Clinical Asthma 
      Evaluation Score 2 (CAES-2), Pediatric Respiratory Assessment Measure (PRAM) and 
      respiratory rate, accessory muscle use, decreased breath sounds (RAD). RESULTS: A 
      total of 1120 observations were used to assess fourteen measurement properties 
      within domains of validity, reliability and utility. All five dyspnoea scores 
      showed overall poor results, scoring insufficiently on more than half of the 
      quality criteria for measurement properties. The AS and PRAM were the most valid 
      with good values on six and moderate values on three properties. Poor results 
      were mainly due to insufficient measurement properties in the validity and 
      reliability domains whereas utility properties were moderate to good in all 
      scores. CONCLUSION: This study shows that commonly used dyspnoea scores show 
      insufficient validity and reliability to allow for clinical use without caution.
FAU - Eggink, Hendriekje
AU  - Eggink H
AD  - Princess Amalia Children's Clinic, Isala, Zwolle, the Netherlands.
AD  - University Medical Center Groningen, Groningen, the Netherlands.
FAU - Brand, Paul
AU  - Brand P
AD  - Princess Amalia Children's Clinic, Isala, Zwolle, the Netherlands.
AD  - University Medical Center Groningen, Groningen, the Netherlands.
FAU - Reimink, Roelien
AU  - Reimink R
AD  - Princess Amalia Children's Clinic, Isala, Zwolle, the Netherlands.
FAU - Bekhof, Jolita
AU  - Bekhof J
AD  - Princess Amalia Children's Clinic, Isala, Zwolle, the Netherlands.
LA  - eng
PT  - Journal Article
PT  - Validation Study
DEP - 20160706
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
RN  - 0 (Bronchodilator Agents)
SB  - IM
MH  - Asthma/*drug therapy
MH  - Bronchodilator Agents/therapeutic use
MH  - Child
MH  - Child, Preschool
MH  - Dyspnea/*diagnosis
MH  - Female
MH  - Humans
MH  - Infant
MH  - Infant, Newborn
MH  - Male
MH  - Observer Variation
MH  - Prospective Studies
MH  - Pulmonary Medicine/standards
MH  - Reproducibility of Results
MH  - *Severity of Illness Index
MH  - Video Recording
PMC - PMC4934692
COIS- Competing Interests: The authors have declared that no competing interests exist.
EDAT- 2016/07/08 06:00
MHDA- 2017/07/25 06:00
PMCR- 2016/07/06
CRDT- 2016/07/08 06:00
PHST- 2016/03/02 00:00 [received]
PHST- 2016/06/05 00:00 [accepted]
PHST- 2016/07/08 06:00 [entrez]
PHST- 2016/07/08 06:00 [pubmed]
PHST- 2017/07/25 06:00 [medline]
PHST- 2016/07/06 00:00 [pmc-release]
AID - PONE-D-16-09065 [pii]
AID - 10.1371/journal.pone.0157724 [doi]
PST - epublish
SO  - PLoS One. 2016 Jul 6;11(7):e0157724. doi: 10.1371/journal.pone.0157724. 
      eCollection 2016.