PMID- 27391933
OWN - NLM
STAT- MEDLINE
DCOM- 20170713
LR  - 20181113
IS  - 1476-5454 (Electronic)
IS  - 0950-222X (Print)
IS  - 0950-222X (Linking)
VI  - 30
IP  - 11
DP  - 2016 Nov
TI  - Spectral-domain optical coherence tomography findings of the macula in 500 
      consecutive patients with uveitis.
PG  - 1415-1423
LID - 10.1038/eye.2016.133 [doi]
AB  - PurposeTo analyze the macular structure in a large series of consecutive patients 
      with different types of uveitis using spectral-domain optical coherence 
      tomography (SD-OCT).Patients and methodsFive hundred eyes of 500 consecutive 
      patients with anterior, intermediate, posterior, and panuveitis underwent 
      standardized macular examination using SD-OCT. Central retinal thickness (CRT), 
      macular volume (MV), and presence of cystoid macular edema (CME), diffuse macular 
      edema (DME), serous retinal detachment (SRD), epiretinal membrane with (ERM+) and 
      without (ERM-) retinal surface wrinkling were determined.ResultsThe anatomic 
      location of inflammation affected significantly CRT and MV (P<0.001, 
      respectively), with the highest values in intermediate and panuveitis. CME was 
      seen in 25% of all uveitic eyes, DME in 11%, SRD in 8%, ERM+ in 18%, and ERM- in 
      13%. CME was most frequent in intermediate (40%) and panuveitis (36%); DME was 
      most frequent in panuveitis (18%) and posterior uveitis (17%); SRD was most 
      frequent in panuveitis (15%) and posterior uveitis (10%); ERM+ was most frequent 
      in panuveitis (45%) and intermediate uveitis (30%); and ERM- was most frequent in 
      intermediate (14%) and posterior uveitis (15%).ConclusionSD-OCT of the macula is 
      recommended for all uveitis patients. CRT, MV, and the incidence of CME were 
      highest in intermediate and panuveitis.
FAU - Grajewski, R S
AU  - Grajewski RS
AD  - Department of Ophthalmology, University of Cologne, Cologne, Germany.
FAU - Boelke, A C
AU  - Boelke AC
AD  - Department of Ophthalmology, University of Cologne, Cologne, Germany.
FAU - Adler, W
AU  - Adler W
AD  - Department of Biometry and Epidemiology, University Erlangen-Nuremberg, Erlangen, 
      Germany.
FAU - Meyer, S
AU  - Meyer S
AD  - Department of Ophthalmology, University of Cologne, Cologne, Germany.
FAU - Caramoy, A
AU  - Caramoy A
AD  - Department of Ophthalmology, University of Cologne, Cologne, Germany.
FAU - Kirchhof, B
AU  - Kirchhof B
AD  - Department of Ophthalmology, University of Cologne, Cologne, Germany.
FAU - Cursiefen, C
AU  - Cursiefen C
AD  - Department of Ophthalmology, University of Cologne, Cologne, Germany.
FAU - Heindl, L M
AU  - Heindl LM
AD  - Department of Ophthalmology, University of Cologne, Cologne, Germany.
LA  - eng
PT  - Journal Article
DEP - 20160708
PL  - England
TA  - Eye (Lond)
JT  - Eye (London, England)
JID - 8703986
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Age of Onset
MH  - Aged
MH  - Aged, 80 and over
MH  - Child
MH  - Child, Preschool
MH  - Epiretinal Membrane/*diagnostic imaging
MH  - Female
MH  - Humans
MH  - Infant
MH  - Macula Lutea/*diagnostic imaging/pathology
MH  - Macular Edema/*diagnostic imaging
MH  - Male
MH  - Middle Aged
MH  - Retinal Detachment/*diagnostic imaging
MH  - *Tomography, Optical Coherence
MH  - Uveitis/classification/*diagnostic imaging
PMC - PMC5108004
EDAT- 2016/07/09 06:00
MHDA- 2017/07/14 06:00
PMCR- 2017/11/01
CRDT- 2016/07/09 06:00
PHST- 2015/07/26 00:00 [received]
PHST- 2016/05/23 00:00 [accepted]
PHST- 2016/07/09 06:00 [pubmed]
PHST- 2017/07/14 06:00 [medline]
PHST- 2016/07/09 06:00 [entrez]
PHST- 2017/11/01 00:00 [pmc-release]
AID - eye2016133 [pii]
AID - 10.1038/eye.2016.133 [doi]
PST - ppublish
SO  - Eye (Lond). 2016 Nov;30(11):1415-1423. doi: 10.1038/eye.2016.133. Epub 2016 Jul 
      8.