PMID- 27396905
OWN - NLM
STAT- MEDLINE
DCOM- 20180221
LR  - 20180221
IS  - 1872-6283 (Electronic)
IS  - 0379-0738 (Linking)
VI  - 266
DP  - 2016 Sep
TI  - A fatal case of paramethoxyamphetamine poisoning and its detection in hair.
PG  - e27-e31
LID - S0379-0738(16)30282-1 [pii]
LID - 10.1016/j.forsciint.2016.06.030 [doi]
AB  - Paramethoxyamphetamine (PMA) is a phenethylamine derivative that is structurally 
      related to 3,4-methylenedioxymethamphetamine (MDMA), but has higher toxicity than 
      MDMA. Here, we report a fatal intoxication case involving PMA. A 36-year-old man 
      was found dead in a hotel room. Toxicological analysis revealed that PMA 
      concentrations were 0.57 and 0.59mg/L in peripheral and heart blood, 
      respectively. Ketamine and diazepam were also detected in his blood. Based on 
      toxicological results and autopsy findings, the cause of death was determined to 
      be acute fatal intoxication with PMA. Hair analysis using gas chromatography/mass 
      spectrometry was performed and PMA was detected at a concentration of 20.1ng/mg 
      after methanol extraction for 20h. This is the first report of the determination 
      of PMA concentration in the hair from a drug abuser.
CI  - Copyright (c) 2016 Elsevier Ireland Ltd. All rights reserved.
FAU - Jang, Moonhee
AU  - Jang M
AD  - National Forensic Service, 139 Jiyang-ro, Yangcheon-Gu, Seoul 158-707, Republic 
      of Korea. Electronic address: jmh1229@korea.kr.
FAU - Yang, Wonkyung
AU  - Yang W
AD  - National Forensic Service, 139 Jiyang-ro, Yangcheon-Gu, Seoul 158-707, Republic 
      of Korea.
FAU - Jeong, Sujin
AU  - Jeong S
AD  - National Forensic Service, 139 Jiyang-ro, Yangcheon-Gu, Seoul 158-707, Republic 
      of Korea.
FAU - Park, Sohyung
AU  - Park S
AD  - National Forensic Service, 139 Jiyang-ro, Yangcheon-Gu, Seoul 158-707, Republic 
      of Korea.
FAU - Kim, Jihyun
AU  - Kim J
AD  - National Forensic Service, 139 Jiyang-ro, Yangcheon-Gu, Seoul 158-707, Republic 
      of Korea.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20160628
PL  - Ireland
TA  - Forensic Sci Int
JT  - Forensic science international
JID - 7902034
RN  - 0 (Amphetamines)
RN  - 0 (Hallucinogens)
RN  - OVB8F8P39Q (4-methoxyamphetamine)
SB  - IM
MH  - Adult
MH  - Amphetamines/*analysis/*poisoning
MH  - Gas Chromatography-Mass Spectrometry
MH  - Hair/*chemistry
MH  - Hallucinogens/*analysis/*poisoning
MH  - Humans
MH  - Male
MH  - Substance-Related Disorders/diagnosis
OTO - NOTNLM
OT  - 3,4-Methylenedioxymethamphetamine (MDMA)
OT  - GC/MS
OT  - Hair
OT  - Intoxication
OT  - Paramethoxyamphetamine (PMA)
EDAT- 2016/07/12 06:00
MHDA- 2018/02/22 06:00
CRDT- 2016/07/12 06:00
PHST- 2016/04/21 00:00 [received]
PHST- 2016/06/17 00:00 [revised]
PHST- 2016/06/21 00:00 [accepted]
PHST- 2016/07/12 06:00 [entrez]
PHST- 2016/07/12 06:00 [pubmed]
PHST- 2018/02/22 06:00 [medline]
AID - S0379-0738(16)30282-1 [pii]
AID - 10.1016/j.forsciint.2016.06.030 [doi]
PST - ppublish
SO  - Forensic Sci Int. 2016 Sep;266:e27-e31. doi: 10.1016/j.forsciint.2016.06.030. 
      Epub 2016 Jun 28.