PMID- 27405892
OWN - NLM
STAT- MEDLINE
DCOM- 20170824
LR  - 20170824
IS  - 1445-5994 (Electronic)
IS  - 1444-0903 (Linking)
VI  - 46
IP  - 7
DP  - 2016 Jul
TI  - Elevated total serum immunoglobulin E (>1000 IU/mL): implications?
PG  - 846-9
LID - 10.1111/imj.13073 [doi]
AB  - Atopic eczema, allergic broncho-pulmonary aspergillosis, helminthic infections 
      and rare primary immunodeficiencies are known to elevate total serum 
      immunoglobulin E (IgE) above 1000 IU/mL. However, of 352 patients with IgE 
      >1000 IU/mL seen in our hospital over a 5-year period, less than 50% had these 
      conditions. Markedly elevated IgE levels in the rest of the patients were 
      associated with asthma, allergic rhinitis and food allergy, instances where the 
      test is of limited diagnostic utility.
CI  - (c) 2016 Royal Australasian College of Physicians.
FAU - Tay, T R
AU  - Tay TR
AD  - Allergy, Immunology and Respiratory Medicine, Alfred Hospital, Melbourne, 
      Victoria, Australia.
FAU - Bosco, J
AU  - Bosco J
AD  - Allergy, Immunology and Respiratory Medicine, Alfred Hospital, Melbourne, 
      Victoria, Australia.
FAU - Aumann, H
AU  - Aumann H
AD  - Department of Haematology, Alfred Hospital, Melbourne, Victoria, Australia.
FAU - O'Hehir, R
AU  - O'Hehir R
AD  - Allergy, Immunology and Respiratory Medicine, Alfred Hospital, Melbourne, 
      Victoria, Australia.
FAU - Hew, M
AU  - Hew M
AD  - Allergy, Immunology and Respiratory Medicine, Alfred Hospital, Melbourne, 
      Victoria, Australia.
AD  - Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, 
      Australia.
LA  - eng
PT  - Journal Article
PL  - Australia
TA  - Intern Med J
JT  - Internal medicine journal
JID - 101092952
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adult
MH  - Aspergillosis, Allergic Bronchopulmonary/blood/*epidemiology
MH  - Asthma/blood/*epidemiology
MH  - Australia
MH  - Dermatitis, Atopic/blood/*epidemiology
MH  - Female
MH  - Food Hypersensitivity/blood/*epidemiology
MH  - Helminthiasis/blood/epidemiology
MH  - Humans
MH  - Immunoglobulin E/*blood
MH  - Immunologic Deficiency Syndromes/blood/epidemiology
MH  - Male
MH  - Middle Aged
MH  - Rhinitis, Allergic/blood/*epidemiology
OTO - NOTNLM
OT  - allergic broncho-pulmonary aspergillosis
OT  - atopy
OT  - eczema
OT  - immunoglobulin E
EDAT- 2016/07/14 06:00
MHDA- 2017/08/25 06:00
CRDT- 2016/07/14 06:00
PHST- 2015/11/09 00:00 [received]
PHST- 2016/03/03 00:00 [revised]
PHST- 2016/03/04 00:00 [accepted]
PHST- 2016/07/14 06:00 [entrez]
PHST- 2016/07/14 06:00 [pubmed]
PHST- 2017/08/25 06:00 [medline]
AID - 10.1111/imj.13073 [doi]
PST - ppublish
SO  - Intern Med J. 2016 Jul;46(7):846-9. doi: 10.1111/imj.13073.