PMID- 27412255 OWN - NLM STAT- MEDLINE DCOM- 20171120 LR - 20181202 IS - 2046-4053 (Electronic) IS - 2046-4053 (Linking) VI - 5 IP - 1 DP - 2016 Jul 13 TI - Appraisal of clinical practice guidelines for management of paediatric type 2 diabetes mellitus using the AGREE II instrument: a systematic review protocol. PG - 111 LID - 10.1186/s13643-016-0288-3 [doi] LID - 111 AB - BACKGROUND: The prevalence of type 2 diabetes mellitus (T2DM) in children and adolescents is increasing. This has spurred the development and publication of clinical practice guidelines (CPGs) for the management of paediatric T2DM. Given the long-term complications of T2DM, optimal management is important to prevent or delay these complications. However, the quality of published CPGs has not yet been empirically evaluated. Our objective is to systematically appraise all published CPGs for the management of T2DM in children and adolescents. METHODS: We will identify all published CPGs that address T2DM in children and adolescents through MEDLINE, Embase, CINAHL, Trip, and the National Guideline Clearinghouse and will screen diabetes and paediatric societies and associations' websites. Search records will be screened in duplicate for inclusion. Grey literature will be covered by systematically searching publications of all relevant diabetes societies and associations and other health organizations for CPGs that meet our inclusion criteria. CPGs deemed eligible for inclusion will be retrieved. Quality assessment will be conducted using the Appraisal of Guidelines for Research and Evaluation II (AGREE II) tool by a team of four appraisers. Scaled scores of the AGREE II will be used to gauge the overall quality of CPGs. DISCUSSION: The results of this review will be disseminated through presentations at local, national, and international conferences and publication in a peer-reviewed journal. The results of this review can help improve the reporting of future guidelines, inform decisions of policy-makers to endorse CPGs, and affect the choice of guideline use in clinical practice. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42016034187. FAU - Zeraatkar, Dena AU - Zeraatkar D AD - Department of Pediatrics, McMaster University, 1280 Main Street West, HSC-3A57, Hamilton, Ontario, L8S 4K1, Canada. AD - Division of Pediatric Endocrinology, McMaster Children's Hospital, 1280 Main Street West, HSC-3A57, Hamilton, Ontario, L8S 4K1, Canada. AD - Department of Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, Ontario, Canada. FAU - Nahari, Ahmed AU - Nahari A AD - Department of Pediatrics, McMaster University, 1280 Main Street West, HSC-3A57, Hamilton, Ontario, L8S 4K1, Canada. AD - Division of Pediatric Endocrinology, McMaster Children's Hospital, 1280 Main Street West, HSC-3A57, Hamilton, Ontario, L8S 4K1, Canada. AD - Department of Pediatrics, King Fahad Central Hospital, Jazan, Saudi Arabia. FAU - Wang, Pei-Wen AU - Wang PW AD - Department of Pediatrics, McMaster University, 1280 Main Street West, HSC-3A57, Hamilton, Ontario, L8S 4K1, Canada. AD - Division of Pediatric Endocrinology, McMaster Children's Hospital, 1280 Main Street West, HSC-3A57, Hamilton, Ontario, L8S 4K1, Canada. FAU - Kearsley, Emily AU - Kearsley E AD - Department of Pediatrics, McMaster University, 1280 Main Street West, HSC-3A57, Hamilton, Ontario, L8S 4K1, Canada. AD - Division of Pediatric Endocrinology, McMaster Children's Hospital, 1280 Main Street West, HSC-3A57, Hamilton, Ontario, L8S 4K1, Canada. FAU - Falzone, Nicole AU - Falzone N AD - Department of Pediatrics, McMaster University, 1280 Main Street West, HSC-3A57, Hamilton, Ontario, L8S 4K1, Canada. AD - Division of Pediatric Endocrinology, McMaster Children's Hospital, 1280 Main Street West, HSC-3A57, Hamilton, Ontario, L8S 4K1, Canada. FAU - Xu, Michael AU - Xu M AD - Department of Pediatrics, McMaster University, 1280 Main Street West, HSC-3A57, Hamilton, Ontario, L8S 4K1, Canada. AD - Division of Pediatric Endocrinology, McMaster Children's Hospital, 1280 Main Street West, HSC-3A57, Hamilton, Ontario, L8S 4K1, Canada. AD - Department of Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, Ontario, Canada. FAU - Banfield, Laura AU - Banfield L AD - Health Sciences Library, McMaster University, Hamilton, Ontario, Canada. FAU - Thabane, Lehana AU - Thabane L AD - Department of Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, Ontario, Canada. AD - Department of Anesthesia, McMaster University, Hamilton, Ontario, Canada. AD - Centre for Evaluation of Medicines, Hamilton, ON, Canada. AD - Biostatistics Unit, St. Joseph's Healthcare Hamilton, Hamilton, Ontario, Canada. FAU - Samaan, M Constantine AU - Samaan MC AUID- ORCID: 0000-0002-6403-4715 AD - Department of Pediatrics, McMaster University, 1280 Main Street West, HSC-3A57, Hamilton, Ontario, L8S 4K1, Canada. samaanc@mcmaster.ca. AD - Division of Pediatric Endocrinology, McMaster Children's Hospital, 1280 Main Street West, HSC-3A57, Hamilton, Ontario, L8S 4K1, Canada. samaanc@mcmaster.ca. AD - Department of Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, Ontario, Canada. samaanc@mcmaster.ca. LA - eng PT - Journal Article DEP - 20160713 PL - England TA - Syst Rev JT - Systematic reviews JID - 101580575 SB - IM MH - Clinical Protocols/*standards MH - Diabetes Mellitus, Type 2/*therapy MH - Humans MH - *Pediatrics MH - Practice Guidelines as Topic/*standards MH - Research Design MH - Systematic Reviews as Topic PMC - PMC4944246 EDAT- 2016/07/15 06:00 MHDA- 2017/11/29 06:00 PMCR- 2016/07/13 CRDT- 2016/07/15 06:00 PHST- 2016/03/08 00:00 [received] PHST- 2016/06/23 00:00 [accepted] PHST- 2016/07/15 06:00 [entrez] PHST- 2016/07/15 06:00 [pubmed] PHST- 2017/11/29 06:00 [medline] PHST- 2016/07/13 00:00 [pmc-release] AID - 10.1186/s13643-016-0288-3 [pii] AID - 288 [pii] AID - 10.1186/s13643-016-0288-3 [doi] PST - epublish SO - Syst Rev. 2016 Jul 13;5(1):111. doi: 10.1186/s13643-016-0288-3.