PMID- 27416765
OWN - NLM
STAT- MEDLINE
DCOM- 20170601
LR  - 20170601
IS  - 1746-0921 (Electronic)
IS  - 1746-0913 (Linking)
VI  - 11
DP  - 2016 Jul
TI  - Current strategies for diagnosis of paracoccidioidomycosis and prospects of 
      methods based on gold nanoparticles.
PG  - 973-85
LID - 10.2217/fmb-2016-0062 [doi]
AB  - Paracoccidioidomycosis (PCM) is a human systemic granulomatous mycosis caused by 
      thermodimorphic fungi from Paracoccidioides genus. The disease is prevalent in 
      Latin America and triggers a serious clinical condition. Consequently, rapid 
      diagnosis and treatment are crucial to prevent progression of the disease, which 
      can result in death. Currently, there are several established methods for PCM 
      diagnosis. However, many of these tests still present challenges in terms of 
      cost, accessibility and efficiency. In this scenario, gold nanoparticles 
      represent a promising alternative since they have particular optical and 
      electronic properties, which allow its use for biomolecules detection. This 
      review will briefly present techniques available for PCM diagnosis and the 
      perspectives of implementation of gold nanoparticles for diagnosis of this 
      mycosis.
FAU - Silva Ferreira, Cyntia
AU  - Silva Ferreira C
AD  - Departamento de Ciencias Biologicas/DECBI - Nucleo de Pesquisas em Ciencias 
      Biologicas/NUPEB - Universidade Federal de Ouro Preto (UFOP), Campus 
      Universitario Morro do Cruzeiro - Ouro Preto, CEP 35400-000, Minas Gerais, 
      Brasil.
FAU - de Castro Ribeiro, Erica Milena
AU  - de Castro Ribeiro EM
AD  - Departamento de Ciencias Biologicas/DECBI - Nucleo de Pesquisas em Ciencias 
      Biologicas/NUPEB - Universidade Federal de Ouro Preto (UFOP), Campus 
      Universitario Morro do Cruzeiro - Ouro Preto, CEP 35400-000, Minas Gerais, 
      Brasil.
FAU - Miranda Goes, Alfredo de
AU  - Miranda Goes Ad
AD  - Departamento de Bioquimica e Imunologia/ICB - Universidade Federal de Minas 
      Gerais (UFMG), Av. Antonio Carlos, Belo Horizonte, CEP 31270-901, Minas Gerais, 
      Brasil.
FAU - Mello Silva, Breno de
AU  - Mello Silva Bd
AD  - Departamento de Ciencias Biologicas/DECBI - Nucleo de Pesquisas em Ciencias 
      Biologicas/NUPEB - Universidade Federal de Ouro Preto (UFOP), Campus 
      Universitario Morro do Cruzeiro - Ouro Preto, CEP 35400-000, Minas Gerais, 
      Brasil.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20160715
PL  - England
TA  - Future Microbiol
JT  - Future microbiology
JID - 101278120
RN  - 0 (Antigens, Fungal)
RN  - 7440-57-5 (Gold)
SB  - IM
MH  - Antigens, Fungal
MH  - *Gold
MH  - Humans
MH  - *Metal Nanoparticles/chemistry
MH  - Paracoccidioides/*isolation & purification
MH  - Paracoccidioidomycosis/*diagnosis/drug therapy/microbiology
OTO - NOTNLM
OT  - Paracoccidioides brasiliensis
OT  - Paracoccidioides lutzii
OT  - diagnosis
OT  - gold nanorods
OT  - gold nanospheres
OT  - paracoccidioidomycosis
EDAT- 2016/07/16 06:00
MHDA- 2017/06/02 06:00
CRDT- 2016/07/16 06:00
PHST- 2016/07/16 06:00 [entrez]
PHST- 2016/07/16 06:00 [pubmed]
PHST- 2017/06/02 06:00 [medline]
AID - 10.2217/fmb-2016-0062 [doi]
PST - ppublish
SO  - Future Microbiol. 2016 Jul;11:973-85. doi: 10.2217/fmb-2016-0062. Epub 2016 Jul 
      15.