PMID- 27429087
OWN - NLM
STAT- MEDLINE
DCOM- 20170502
LR  - 20170817
IS  - 1536-4798 (Electronic)
IS  - 0277-3740 (Linking)
VI  - 35
IP  - 10
DP  - 2016 Oct
TI  - Evaluation of Early Graft Detachment After Descemet Membrane Endothelial 
      Keratoplasty Using New Swept-Source Optical Coherence Tomography.
PG  - 1279-84
LID - 10.1097/ICO.0000000000000925 [doi]
AB  - PURPOSE: To evaluate the ability of Swept-source optical coherence tomography 
      (SS-OCT) in detecting early endothelial graft detachment after Descemet membrane 
      endothelial keratoplasty (DMEK) and to determine the possible causes of graft 
      detachment using 2 different protocols for anterior segment (AS) imaging. 
      METHODS: Eight eyes from 8 consecutive DMEK surgeries were evaluated. 
      High-resolution images were captured with SS-OCT using 2 different radial 
      protocols for AS imaging (16- and 6-mm radial protocols). Central and peripheral 
      corneal changes were evaluated. RESULTS: All eyes developed early graft 
      detachment detectable with the SS-OCT. The 16-mm radial protocol scanned the 
      cornea detecting early graft detachment in 6 out of 8 cases. The 6-mm radial 
      protocol provided detailed images of the cornea, detecting early detachment in 
      all cases. Stromal irregularities and small remnants only detectable using SS-OCT 
      were the possible cause of detachment in 3 cases. One of the 8 eyes had air 
      reinjection. The detachment in that eye was apparent by slit-lamp examination. 
      The detachments spontaneously resolved in the other 7 eyes. AS SS-OCT evaluation 
      was found to have added diagnostic value to biomicroscopy in 5 of these eyes 
      (64.5%). CONCLUSIONS: AS SS-OCT is sensitive in detecting early graft detachment 
      after DMEK. The 16-mm radial protocol of Triton SS-OCT is superior regarding 
      quick scan of the entire cornea providing a general visualization of the DMEK 
      graft. The 6-mm radial protocol provides detailed corneal imaging of a selected 
      area, which is useful for evaluating structural alterations that are not 
      detectable with larger scans and may affect the adherence of the endothelial 
      graft.
FAU - Satue, Maria
AU  - Satue M
AD  - *IIS-Aragon, Instituto Aragones de Ciencias de la Salud (IACS), Zaragoza, Spain; 
      daggerDepartment of Ophthalmology, Miguel Servet University Hospital, Zaragoza, Spain; 
      and double daggerDepartment of Ophthalmology, Naval Hospital, Athens, Greece.
FAU - Idoipe, Miriam
AU  - Idoipe M
FAU - Sanchez-Perez, Antonio
AU  - Sanchez-Perez A
FAU - Liarakos, Vasilis S
AU  - Liarakos VS
FAU - Mateo, Antonio
AU  - Mateo A
FAU - Garcia-Martin, Elena
AU  - Garcia-Martin E
FAU - Polo, Vicente
AU  - Polo V
FAU - Gavin, Alicia
AU  - Gavin A
FAU - Brito, Carlos
AU  - Brito C
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Cornea
JT  - Cornea
JID - 8216186
SB  - IM
MH  - Anterior Eye Segment/*diagnostic imaging
MH  - Cell Count
MH  - Corneal Pachymetry
MH  - Descemet Stripping Endothelial Keratoplasty/*adverse effects
MH  - Endothelium, Corneal/diagnostic imaging/*pathology
MH  - Fuchs' Endothelial Dystrophy/*surgery
MH  - Graft Rejection/*diagnostic imaging/*etiology
MH  - Graft Survival
MH  - Humans
MH  - Intraoperative Complications
MH  - Risk Factors
MH  - Tomography, Optical Coherence/*methods
EDAT- 2016/07/19 06:00
MHDA- 2017/05/04 06:00
CRDT- 2016/07/19 06:00
PHST- 2016/07/19 06:00 [entrez]
PHST- 2016/07/19 06:00 [pubmed]
PHST- 2017/05/04 06:00 [medline]
AID - 10.1097/ICO.0000000000000925 [doi]
PST - ppublish
SO  - Cornea. 2016 Oct;35(10):1279-84. doi: 10.1097/ICO.0000000000000925.