PMID- 27430920
OWN - NLM
STAT- MEDLINE
DCOM- 20170110
LR  - 20181202
IS  - 1001-0939 (Print)
IS  - 1001-0939 (Linking)
VI  - 39
IP  - 7
DP  - 2016 Jul
TI  - [A study of the diagnostic value of endobronchial ultrasound guide sheath 
      transbronchial lung biopsy combined with virtual bronchoscopic navigation in 
      peripheral pulmonary lesions].
PG  - 509-13
LID - 10.3760/cma.j.issn.1001-0939.2016.07.004 [doi]
AB  - OBJECTIVE: To evaluate the diagnostic value of endobronchial ultrasound guide 
      sheath transbronchial lung biopsy (EBUS-GS-TBLB) combined with virtual 
      bronchoscopic navigation (VBN) in peripheral pulmonary lesions (PPLs). METHODS: 
      Cases with a PPL identified by computed tomography in Affiliated Hospital of 
      Medical College of Ningbo University underwent EBUS-GS-TBLB with or without VBN 
      randomly between Nov. 2014 to Aug. 2015. X-ray guidance was not performed in 
      these cases. The sensitivity and the operation time were evaluated in the 2 
      groups. RESULTS: A total of 184 patients were enrolled and completed this study. 
      Among them 117 were males and 67 were females. There were 93 cases in the group 
      of EBUS-GS-TBLB with VBN, and 91 in the group without VBN. The diagnostic 
      sensitivity of VBN group was 72.04%(67/93). Among these positive cases, 64.1% 
      cases (43/67) were malignant tumors, and 35.9% cases (24/67) were benign lesions. 
      The mean operation time was (45+/-10)min. In the group without VBN, the diagnostic 
      sensitivity was 69.23%(63/91), including 33 malignant tumors(52.4%, 33/63), and 
      30 benign lesions(47.6%, 30/63). The mean operation time was (55+/-10)min. There 
      was no significant difference between EBUS-GS-TBLB with VBN group and 
      EBUS-GS-TBLB without VBN group in diagnostic sensitivity (chi(2)=0.175, P=0.747). 
      But there was a significant difference in the mean operation time between the 2 
      groups (t=6.522, P<0.001). EBUS-GS-TBLB was well tolerated. No severe 
      procedure-related complications such as pneumothorax and hemoptysis were 
      observed. CONCLUSION: VBN cannot improve the diagnostic sensitivity, but it can 
      clear the location of lesion, and shorten the operation time. This technique 
      helps to abandon the X-ray guidance. EBUS-GS-TBLB combined with VBN is a safe and 
      effective technique for PPLs.
FAU - Chen, Z B
AU  - Chen ZB
AD  - Department of Respiratory, Affiliated Hospital of Ningbo University Medical 
      College, Ningbo 315020, China.
FAU - Jin, Y P
AU  - Jin YP
FAU - Yu, Y M
AU  - Yu YM
FAU - Zhu, D P
AU  - Zhu DP
FAU - Ma, H Y
AU  - Ma HY
FAU - Chen, L
AU  - Chen L
FAU - Zhang, Y
AU  - Zhang Y
FAU - Ding, Q L
AU  - Ding QL
FAU - Deng, Z C
AU  - Deng ZC
LA  - chi
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - China
TA  - Zhonghua Jie He He Hu Xi Za Zhi
JT  - Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal 
      of tuberculosis and respiratory diseases
JID - 8712226
SB  - IM
MH  - Biopsy/*methods
MH  - Bronchoscopy/*methods
MH  - Endosonography
MH  - Female
MH  - Humans
MH  - Lung/*diagnostic imaging/pathology
MH  - Lung Neoplasms/diagnostic imaging
MH  - Male
MH  - Tomography, X-Ray Computed
MH  - Ultrasonography
EDAT- 2016/07/20 06:00
MHDA- 2017/01/11 06:00
CRDT- 2016/07/20 06:00
PHST- 2016/07/20 06:00 [entrez]
PHST- 2016/07/20 06:00 [pubmed]
PHST- 2017/01/11 06:00 [medline]
AID - 10.3760/cma.j.issn.1001-0939.2016.07.004 [doi]
PST - ppublish
SO  - Zhonghua Jie He He Hu Xi Za Zhi. 2016 Jul;39(7):509-13. doi: 
      10.3760/cma.j.issn.1001-0939.2016.07.004.