PMID- 27431801
OWN - NLM
STAT- MEDLINE
DCOM- 20170731
LR  - 20240325
IS  - 1471-244X (Electronic)
IS  - 1471-244X (Linking)
VI  - 16
DP  - 2016 Jul 19
TI  - Depression treatment decreases healthcare expenditures among working age patients 
      with comorbid conditions and type 2 diabetes mellitus along with newly-diagnosed 
      depression.
PG  - 247
LID - 10.1186/s12888-016-0964-9 [doi]
LID - 247
AB  - BACKGROUND: There are many studies in the literature on the association between 
      depression treatment and health expenditures. However, there is a knowledge gap 
      in examining this relationship taking into account coexisting chronic conditions 
      among patients with diabetes. We aim to analyze the association between 
      depression treatment and healthcare expenditures among adults with Type 2 
      Diabetes Mellitus (T2DM) and newly-diagnosed depression, with consideration of 
      coexisting chronic physical conditions. METHODS: We used multi-state Medicaid 
      data (2000-2008) and adopted a retrospective longitudinal cohort design. Medical 
      conditions were identified using diagnosis codes (ICD-9-CM and CPT systems). 
      Healthcare expenditures were aggregated for each month for 12 months. Types of 
      coexisting chronic physical conditions were hierarchically grouped into: 
      dominant, concordant, discordant, and both concordant and discordant. Depression 
      treatment categories were as follows: antidepressants or psychotherapy, both 
      antidepressants and psychotherapy, and no treatment. We used linear mixed-effects 
      models on log-transformed expenditures (total and T2DM-related) to examine the 
      relationship between depression treatment and health expenditures. The analyses 
      were conducted on the overall study population and also on subgroups that had 
      coexisting chronic physical conditions. RESULTS: Total healthcare expenditures 
      were reduced by treatment with antidepressants (16 % reduction), psychotherapy 
      (22 %), and both therapy types in combination (28 %) compared to no depression 
      treatment. Treatment with both antidepressants and psychotherapy was associated 
      with reductions in total healthcare expenditures among all groups that had a 
      coexisting chronic physical condition. CONCLUSIONS: Among adults with T2DM and 
      chronic conditions, treatment with both antidepressants and psychotherapy may 
      result in economic benefits.
FAU - Bhattacharya, Rituparna
AU  - Bhattacharya R
AD  - Humana Inc, Clinical Data Analytics (CODA), Tucson, AZ, USA.
FAU - Shen, Chan
AU  - Shen C
AD  - Department of Health Services Research and Biostatistics, University of Texas MD 
      Anderson Cancer Center, Houston, TX, USA. cshen@mdanderson.org.
AD  - Departments of Health Services Research, The University of Texas MD Anderson 
      Cancer Center, 1400 Pressler Street, Unit 1444, Houston, TX, 77030, USA. 
      cshen@mdanderson.org.
FAU - Wachholtz, Amy B
AU  - Wachholtz AB
AD  - Department of Psychiatry, University of Massachusetts Medical School, Worcester, 
      MA, USA.
FAU - Dwibedi, Nilanjana
AU  - Dwibedi N
AD  - Department of Pharmaceutical Systems and Policy, School of Pharmacy, West 
      Virginia University, Morgantown, WV, USA.
FAU - Sambamoorthi, Usha
AU  - Sambamoorthi U
AD  - Department of Social & Behavioral Sciences, School of Public Health, West 
      Virginia University, Morgantown, WV, USA.
LA  - eng
GR  - K23 DA030397/DA/NIDA NIH HHS/United States
GR  - U54 GM104942/GM/NIGMS NIH HHS/United States
PT  - Journal Article
DEP - 20160719
PL  - England
TA  - BMC Psychiatry
JT  - BMC psychiatry
JID - 100968559
RN  - 0 (Antidepressive Agents)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Antidepressive Agents/therapeutic use
MH  - Chronic Disease/economics/*epidemiology
MH  - Combined Modality Therapy/economics
MH  - Comorbidity
MH  - Depression/economics/*epidemiology/therapy
MH  - Diabetes Mellitus, Type 2/economics/*epidemiology/therapy
MH  - Female
MH  - Health Care Costs/statistics & numerical data
MH  - Health Expenditures/*statistics & numerical data
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Psychotherapy
MH  - Retrospective Studies
MH  - United States
PMC - PMC4950075
OTO - NOTNLM
OT  - Comorbidity
OT  - Depression
OT  - Healthcare expenditures
OT  - Type 2 diabetes mellitus
EDAT- 2016/07/20 06:00
MHDA- 2017/08/02 06:00
PMCR- 2016/07/19
CRDT- 2016/07/20 06:00
PHST- 2016/01/11 00:00 [received]
PHST- 2016/07/08 00:00 [accepted]
PHST- 2016/07/20 06:00 [entrez]
PHST- 2016/07/20 06:00 [pubmed]
PHST- 2017/08/02 06:00 [medline]
PHST- 2016/07/19 00:00 [pmc-release]
AID - 10.1186/s12888-016-0964-9 [pii]
AID - 964 [pii]
AID - 10.1186/s12888-016-0964-9 [doi]
PST - epublish
SO  - BMC Psychiatry. 2016 Jul 19;16:247. doi: 10.1186/s12888-016-0964-9.