PMID- 27432097 OWN - NLM STAT- MEDLINE DCOM- 20170327 LR - 20181202 IS - 1349-7235 (Electronic) IS - 0918-2918 (Linking) VI - 55 IP - 14 DP - 2016 TI - Fulminant Type 1 Diabetes Mellitus Presenting 11 Days after Delivery in a Patient of Mixed Genetic Background. PG - 1881-5 LID - 10.2169/internalmedicine.55.6052 [doi] AB - The patient was a 25-year-old woman whose paternal family was Japanese, maternal grandfather was Filipino, and maternal grandmother was Chinese. Eleven days after delivery, she presented with excessive thirst and disturbed consciousness due to diabetic ketoacidosis. She was diagnosed as having fulminant type 1 diabetes associated with pregnancy (PF). The antibody concentration against glutamic acid decarboxylase was 1.2 (<1.5) U/mL, and human leukocyte antigen (HLA) class II haplotypes were DRB1*04:10-DQB1*03:02 and DRB1*15:02-DQB1*05:01. The present case had unique HLA class II haplotypes that have not been previously reported in association with PF. FAU - Furukawa, Shoko AU - Furukawa S AD - Department of Endocrinology and Metabolism, Tsukuba University Hospital Mito Clinical Education and Training Center, Mito Kyodo General Hospital, Japan. FAU - Fujihara, Kazuya AU - Fujihara K FAU - Kumagai, Ryo AU - Kumagai R FAU - Isono, Momoko AU - Isono M FAU - Yagyu, Hiroaki AU - Yagyu H LA - eng PT - Case Reports PT - Journal Article DEP - 20160715 PL - Japan TA - Intern Med JT - Internal medicine (Tokyo, Japan) JID - 9204241 RN - 0 (HLA Antigens) RN - EC 4.1.1.15 (Glutamate Decarboxylase) SB - IM MH - Adult MH - Diabetes Mellitus, Type 1/*classification/*diagnosis/immunology MH - Diabetes, Gestational/*classification/*diagnosis MH - Diabetic Ketoacidosis/metabolism MH - Female MH - Genetic Background MH - Glutamate Decarboxylase/immunology MH - HLA Antigens/immunology MH - Haplotypes MH - Humans MH - Pregnancy EDAT- 2016/07/20 06:00 MHDA- 2017/03/28 06:00 CRDT- 2016/07/20 06:00 PHST- 2016/07/20 06:00 [entrez] PHST- 2016/07/20 06:00 [pubmed] PHST- 2017/03/28 06:00 [medline] AID - 10.2169/internalmedicine.55.6052 [doi] PST - ppublish SO - Intern Med. 2016;55(14):1881-5. doi: 10.2169/internalmedicine.55.6052. Epub 2016 Jul 15.