PMID- 27436444
OWN - NLM
STAT- MEDLINE
DCOM- 20170410
LR  - 20170410
IS  - 1873-2534 (Electronic)
IS  - 0165-2427 (Linking)
VI  - 177
DP  - 2016 Sep
TI  - Mycoplasma hyorhinis is a potential pathogen of porcine respiratory disease 
      complex that aggravates pneumonia caused by porcine reproductive and respiratory 
      syndrome virus.
PG  - 48-51
LID - S0165-2427(16)30117-9 [pii]
LID - 10.1016/j.vetimm.2016.06.008 [doi]
AB  - The porcine respiratory disease complex (PRDC) caused by numerous bacterial and 
      viral agents has a great impact on pig industry worldwide. Although Mycoplasma 
      hyorhinis (Mhr) has been frequently isolated from lung lesions from pigs with 
      PRDC, the pathological importance of Mhr may have been underestimated. In this 
      study, 383 serum samples obtained from seven herds with a history of PRDC were 
      tested for specific antibodies to Mhr, Mycoplasma hyopneumoniae (Mhp), and 
      porcine reproductive and respiratory syndrome virus (PRRSV). Seropositive rates 
      of PRRSV were significantly correlated with those of Mhr (correlation 
      coefficient, 0.862; P-value, 0.013), but not with those of Mhp (correlation 
      coefficient, -0.555; P-value, 0.196). In vivo experiments demonstrated that pigs 
      co-infected with Mhr and PRRSV induced more severe lung lesions than pigs 
      infected with Mhr or PRRSV alone. These findings suggest that Mhr is closely 
      associated with pneumonia caused by PRRSV and provide important information on 
      Mhr pathogenesis within PRDC. Therefore, effective PRDC control strategies should 
      also consider the potential impact of Mhr in the pathogenesis of PRDC.
CI  - Copyright (c) 2016 Elsevier B.V. All rights reserved.
FAU - Lee, Jung-Ah
AU  - Lee JA
AD  - College of Veterinary Medicine, Konkuk University, Seoul 143-701, Republic of 
      Korea; Division of Vaccine Research, National Institute of Health, Centers for 
      Disease Control and Prevention, Osong-eup, CheongJu, Chungcheongbuk-do 363-951, 
      Republic of Korea.
FAU - Oh, Yu-Ri
AU  - Oh YR
AD  - College of Veterinary Medicine, Konkuk University, Seoul 143-701, Republic of 
      Korea.
FAU - Hwang, Min-A
AU  - Hwang MA
AD  - College of Veterinary Medicine, Konkuk University, Seoul 143-701, Republic of 
      Korea.
FAU - Lee, Joong-Bok
AU  - Lee JB
AD  - College of Veterinary Medicine, Konkuk University, Seoul 143-701, Republic of 
      Korea.
FAU - Park, Seung-Yong
AU  - Park SY
AD  - College of Veterinary Medicine, Konkuk University, Seoul 143-701, Republic of 
      Korea.
FAU - Song, Chang-Seon
AU  - Song CS
AD  - College of Veterinary Medicine, Konkuk University, Seoul 143-701, Republic of 
      Korea.
FAU - Choi, In-Soo
AU  - Choi IS
AD  - College of Veterinary Medicine, Konkuk University, Seoul 143-701, Republic of 
      Korea.
FAU - Lee, Sang-Won
AU  - Lee SW
AD  - College of Veterinary Medicine, Konkuk University, Seoul 143-701, Republic of 
      Korea. Electronic address: odssey@konkuk.ac.kr.
LA  - eng
PT  - Journal Article
DEP - 20160616
PL  - Netherlands
TA  - Vet Immunol Immunopathol
JT  - Veterinary immunology and immunopathology
JID - 8002006
RN  - 0 (Antibodies, Bacterial)
RN  - 0 (Antibodies, Viral)
SB  - IM
MH  - Animals
MH  - Antibodies, Bacterial/blood
MH  - Antibodies, Viral/blood
MH  - Coinfection/etiology/microbiology/virology
MH  - Lung/microbiology/pathology/virology
MH  - Mycoplasma hyorhinis/immunology/*pathogenicity
MH  - Pneumonia of Swine, Mycoplasmal/etiology/microbiology/virology
MH  - Porcine Reproductive and Respiratory Syndrome/*etiology/*microbiology/virology
MH  - Porcine respiratory and reproductive syndrome virus/immunology/*pathogenicity
MH  - Sus scrofa
MH  - Swine
MH  - Virulence
OTO - NOTNLM
OT  - Mycoplasma hyopneumoniae
OT  - Mycoplasma hyorhinis
OT  - Porcine reproductive and respiratory syndrome virus
OT  - Porcine respiratory disease complex
EDAT- 2016/07/21 06:00
MHDA- 2017/04/11 06:00
CRDT- 2016/07/21 06:00
PHST- 2015/08/05 00:00 [received]
PHST- 2016/05/20 00:00 [revised]
PHST- 2016/06/15 00:00 [accepted]
PHST- 2016/07/21 06:00 [entrez]
PHST- 2016/07/21 06:00 [pubmed]
PHST- 2017/04/11 06:00 [medline]
AID - S0165-2427(16)30117-9 [pii]
AID - 10.1016/j.vetimm.2016.06.008 [doi]
PST - ppublish
SO  - Vet Immunol Immunopathol. 2016 Sep;177:48-51. doi: 10.1016/j.vetimm.2016.06.008. 
      Epub 2016 Jun 16.